Search Results - "WONG, S. T"

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview by Wong, Alice S T, Che, Chi-Ming, Leung, Kar-Wah

“…Cancer is one of the leading causes of death worldwide. Ginseng, a key ingredient in traditional Chinese medicine, shows great promise as a new treatment…”
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Two-component protein-engineered physical hydrogels for cell encapsulation by Wong Po Foo, Cheryl T.S, Lee, Ji Seok, Mulyasasmita, Widya, Parisi-Amon, Andreina, Heilshorn, Sarah C

“…Current protocols to encapsulate cells within physical hydrogels require substantial changes in environmental conditions (pH, temperature, or ionic strength)…”
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Sialyl Lewisx-P-selectin cascade mediates tumor–mesothelial adhesion in ascitic fluid shear flow by Li, Shan-Shan, Ip, Carman K. M., Tang, Matthew Y. H., Tang, Maggie K. S., Tong, Yin, Zhang, Jiangwen, Hassan, Ayon Ahmed, Mak, Abby S. C., Yung, Susan, Chan, Tak-Mao, Ip, Philip P., Lee, Cheuk Lun, Chiu, Philip C. N., Lee, Leo Tsz On, Lai, Hung-Cheng, Zeng, Jin-Zhang, Shum, Ho Cheung, Wong, Alice S. T.

“…Organ-specific colonization suggests that specific cell–cell recognition is essential. Yet, very little is known about this particular interaction. Moreover,…”
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Mammalian lectin arrays for screening host–microbe interactions by Jégouzo, Sabine A.F., Nelson, Conor, Hardwick, Thomas, Wong, S.T. Angel, Lau, Noel Kuan Kiat, Neoh, Gaik Kin Emily, Castellanos-Rueda, Rocío, Huang, Zhiyao, Mignot, Benjamin, Hirdaramani, Aanya, Howitt, Annie, Frewin, Kathryn, Shen, Zheng, 沈, 诤, Fox, Rhys J., Wong, Rachel, Ando, Momoko, Emony, Lauren, Zhu, Henderson, Holder, Angela, Werling, Dirk, Krishnan, Nitya, Robertson, Brian D., Clements, Abigail, Taylor, Maureen E., Drickamer, Kurt

“…Many members of the C-type lectin family of glycan-binding receptors have been ascribed roles in the recognition of microorganisms and serve as key receptors…”
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Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface by Tang, Maggie K. S., Yue, Patrick Y. K., Ip, Philip P., Huang, Rui-Lan, Lai, Hung-Cheng, Cheung, Annie N. Y., Tse, Ka Yu, Ngan, Hextan Y. S., Wong, Alice S. T.

“…The limitations of current anti-angiogenic therapies necessitate other targets with complimentary mechanisms. Here, we show for the first time that soluble…”
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Ascitic fluid shear stress in concert with hepatocyte growth factor drive stemness and chemoresistance of ovarian cancer cells via the c-Met-PI3K/Akt-miR-199a-3p signaling pathway by Hassan, Ayon A., Artemenko, Margarita, Tang, Maggie K. S., Shi, Zeyu, Chen, Lin-Yu, Lai, Hung-Cheng, Yang, Zhenyu, Shum, Ho-Cheung, Wong, Alice S. T.

“…Overcoming drug resistance is an inevitable challenge to the success of cancer treatment. Recently, in ovarian cancer, a highly chemoresistant tumor, we…”
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p70 S6 kinase in the control of actin cytoskeleton dynamics and directed migration of ovarian cancer cells by Ip, C K M, Cheung, A N Y, Ngan, H Y S, Wong, A S T

“…Ovarian cancer is highly metastatic with a poor prognosis. The serine/threonine kinase, p70 S6 kinase (p70 S6K ), which is a downstream effector of…”
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Chemoresistance in ovarian cancer: exploiting cancer stem cell metabolism by Li, Shan Shan, Ma, Jing, Wong, Alice S T

“…Ovarian cancer is most deadly gynecologic malignancies worldwide. Chemotherapy is the mainstay treatment for ovarian cancer. Despite the initial response is…”
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Complementary and alternative medicine (CAM) information and support needs of Chinese-speaking cancer patients by Balneaves, Lynda G., Wong, M. E., Porcino, A. J., Truant, T. L. O., Thorne, S. E., Wong, S. T.

“…Purpose Complementary and alternative medicine (CAM) is popular among Chinese-speaking cancer patients (CSCPs), but little research examines CAM use by…”
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Orphan Nuclear Receptor Nur77 Mediates the Lethal Endoplasmic Reticulum Stress and Therapeutic Efficacy of Cryptomeridiol in Hepatocellular Carcinoma by Li, Xudan, Chen, Quancheng, Liu, Jie, Lai, Shenjin, Zhang, Minda, Zhen, Tidong, Hu, Hongyu, Gao, Xiang, Wong, Alice S T, Zeng, Jin-Zhang

“…Hepatocellular carcinoma (HCC) commonly possesses chronical elevation of IRE1α-ASK1 signaling. Orphan nuclear receptor Nur77, a promising therapeutic target in…”
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Bayesian mortality forecasting with overdispersion by Wong, Jackie S.T., Forster, Jonathan J., Smith, Peter W.F.

“…The ability to produce accurate mortality forecasts, accompanied by a set of representative uncertainty bands, is crucial in the planning of public retirement…”
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A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility by Leung, W K C, Ching, A K K, Chan, A W H, Poon, T C W, Mian, H, Wong, A S T, To, K-F, Wong, N

“…The PFTK1 gene encodes a cdc2-related serine/threonine protein kinase that has been shown to confer cell migratory properties in hepatocellular carcinoma…”
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p70 S6 kinase as a therapeutic target in cancers: More than just an mTOR effector by Artemenko, Margarita, Zhong, Sophia S.W., To, Sally K.Y., Wong, Alice S.T.

“…p70 S6 kinase (p70S6K) is best known for its regulatory roles in protein synthesis and cell growth by phosphorylating its primary substrate, ribosomal protein…”
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Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer by Cheung, L W T, Leung, P C K, Wong, A S T

“…Gonadotropin-releasing hormone (GnRH) receptor expression is often elevated in ovarian cancer, but its potential role in ovarian cancer metastasis has just…”
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Stemness and chemoresistance in epithelial ovarian carcinoma cells under shear stress by Ip, Carman K. M., Li, Shan-Shan, Tang, Matthew Y. H., Sy, Samuel K. H., Ren, Yong, Shum, Ho Cheung, Wong, Alice S. T.

“…One of greatest challenges to the successful treatment of cancer is drug resistance. An exciting approach is the eradication of cancer stem cells (CSCs)…”
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Development and Implementation of an Intergenerational Bonding Program in a Co-Located Model: A Case Study in Singapore by Yeh, I-Ling, Wong, Sebastian Ye Xun, Safaruan, Lydia Safrina Binte, Kang, Yuan Qi, Wong, May S. T, Wilson, Ingrid M

“…There is a well-established body of evidence that intergenerational bonding programs (IGPs) can improve the overall well-being of older adults and strengthen…”
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Ginsenoside-Rg1 induces angiogenesis via non-genomic crosstalk of glucocorticoid receptor and fibroblast growth factor receptor-1 by CHEUNG, Lydia W. T, LEUNG, Kar Wah, WONG, Chris K. C, WONG, Ricky N. S, WONG, Alice S. T

“…Ginsenoside-Rg1, the most prevalent active constituent of Panax ginseng, has been shown to possess potent pro-angiogenic properties and therefore poses special…”
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Association between sleeping hours, working hours and obesity in Hong Kong Chinese: the 'better health for better Hong Kong' health promotion campaign by Ko, G.T.C, Chan, J.C.N, Chan, A.W.Y, Wong, P.T.S, Hui, S.S.C, Tong, S.D.Y, Ng, S.M, Chow, F, Chan, C.L.W

“…Objective: To study the inter-relationships between sleeping hours, working hours and obesity in subjects from a working population. Research design: A…”
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Synergistic Effects of Epidermal Growth Factor and Hepatocyte Growth Factor on Human Ovarian Cancer Cell Invasion and Migration: Role of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase by Zhou, Hong Y, Pon, Yuen L, Wong, Alice S. T

“…Ovarian cancer is the primary cause of death from gynecological malignancies with a poor prognosis characterized by widespread peritoneal dissemination…”
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Bilateral breast multiple myeloma: a case report by Mo, C K M, Lai, A Y T, Lo, S S W, Wong, T S, Wong, W W C

“…Dual-tracer positron emission tomography (PET)/CT was performed in early March 2020 at a private institution to assess disease involvement. There were multiple…”
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