Search Results - "WONG, John"

COVID-19 in Singapore—Current Experience: Critical Global Issues That Require Attention and Action by Wong, John E. L, Leo, Yee Sin, Tan, Chorh Chuan

“…This Viewpoint discusses public health measures implemented in Singapore to manage potential COVID-19 infection based on the country's experience with SARS in…”
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Singapore's health-care system: key features, challenges, and shifts by Tan, Chorh Chuan, Lam, Carolyn S P, Matchar, David B, Zee, Yoong Kang, Wong, John E L

“…Since Singapore became an independent nation in 1965, the development of its health-care system has been underpinned by an emphasis on personal responsibility…”
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Pandemic Surge Models in the Time of Severe Acute Respiratory Syndrome Coronavirus 2: Wrong or Useful? by Wong, John B

“…With 2 million confirmed cases and more than 100 000 deaths worldwide, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has generated…”
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Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018 by O’Hearn, Meghan, Lauren, Brianna N., Wong, John B., Kim, David D., Mozaffarian, Dariush

“…Few studies have assessed U.S. cardiometabolic health trends—optimal levels of multiple risk factors and absence of clinical cardiovascular disease (CVD)—or…”
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Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement by Davidson, Karina W, Barry, Michael J, Mangione, Carol M, Cabana, Michael, Caughey, Aaron B, Davis, Esa M, Donahue, Katrina E, Doubeni, Chyke A, Krist, Alex H, Kubik, Martha, Li, Li, Ogedegbe, Gbenga, Owens, Douglas K, Pbert, Lori, Silverstein, Michael, Stevermer, James, Tseng, Chien-Wen, Wong, John B

“…IMPORTANCE: Colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52 980 persons in the US projected to die of…”
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The Predictive Approaches to Treatment effect Heterogeneity (PATH) Statement by Kent, David M, Paulus, Jessica K, van Klaveren, David, D'Agostino, Ralph, Goodman, Steve, Hayward, Rodney, Ioannidis, John P A, Patrick-Lake, Bray, Morton, Sally, Pencina, Michael, Raman, Gowri, Ross, Joseph S, Selker, Harry P, Varadhan, Ravi, Vickers, Andrew, Wong, John B, Steyerberg, Ewout W

“…Heterogeneity of treatment effect (HTE) refers to the nonrandom variation in the magnitude or direction of a treatment effect across levels of a covariate, as…”
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Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES) by de Ferranti, Sarah D, Rodday, Angie Mae, Mendelson, Michael M, Wong, John B, Leslie, Laurel K, Sheldrick, R Christopher

“…BACKGROUND—The prevalence of familial hypercholesterolemia (FH) is commonly reported as 1 in 500. European reports suggest a higher prevalence; the US FH…”
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A Systematic Review of Stakeholder Engagement in Comparative Effectiveness and Patient-Centered Outcomes Research by Concannon, Thomas W., Fuster, Melissa, Saunders, Tully, Patel, Kamal, Wong, John B., Leslie, Laurel K., Lau, Joseph

“…ABSTRACT OBJECTIVES We conducted a review of the peer-reviewed literature since 2003 to catalogue reported methods of stakeholder engagement in comparative…”
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Non-Binary and Binary Gender Identity in Australian Trans and Gender Diverse Individuals by Cheung, Ada S., Leemaqz, Shalem Y., Wong, John W. P., Chew, Denise, Ooi, Olivia, Cundill, Pauline, Silberstein, Nicholas, Locke, Peter, Zwickl, Sav, Grayson, Ren, Zajac, Jeffrey D., Pang, Ken C.

“…Many trans and gender diverse (TGD) people have gender identities that are not exclusively male or female but instead fall in-between or outside of the gender…”
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Hepatitis B Virus Reactivation and Prophylaxis During Solid Tumor Chemotherapy: A Systematic Review and Meta-analysis by Paul, Sonali, Saxena, Akriti, Terrin, Norma, Viveiros, Kathleen, Balk, Ethan M, Wong, John B

“…Solid tumor chemotherapy regimens pose a risk for hepatitis B virus (HBV) reactivation, but screening and antiviral prophylaxis remains controversial because…”
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scSNPdemux: a sensitive demultiplexing pipeline using single nucleotide polymorphisms for improved pooled single-cell RNA sequencing analysis by Wong, John K. L, Jassowicz, Lena, Herold-Mende, Christel, Seiffert, Martina, Mallm, Jan-Philipp, Lichter, Peter, Zapatka, Marc

“…Abstract Background Here we present scSNPdemux, a sample demultiplexing pipeline for single-cell RNA sequencing data using natural genetic variations in…”
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Methadone continuation versus forced withdrawal on incarceration in a combined US prison and jail: a randomised, open-label trial by Rich, Josiah D, Prof, McKenzie, Michelle, MPH, Larney, Sarah, PhD, Wong, John B, MD, Tran, Liem, MS, Clarke, Jennifer, MD, Noska, Amanda, MD, Reddy, Manasa, BA, Zaller, Nickolas, PhD

“…Summary Background Methadone is an effective treatment for opioid dependence. When people who are receiving methadone maintenance treatment for opioid…”
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Screening for Lung Cancer: US Preventive Services Task Force Recommendation Statement by Krist, Alex H, Davidson, Karina W, Mangione, Carol M, Barry, Michael J, Cabana, Michael, Caughey, Aaron B, Davis, Esa M, Donahue, Katrina E, Doubeni, Chyke A, Kubik, Martha, Landefeld, C. Seth, Li, Li, Ogedegbe, Gbenga, Owens, Douglas K, Pbert, Lori, Silverstein, Michael, Stevermer, James, Tseng, Chien-Wen, Wong, John B

“…IMPORTANCE: Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated 228 820 persons were diagnosed…”
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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity by Hanna, Bola S., Llaó-Cid, Laura, Iskar, Murat, Roessner, Philipp M., Klett, Lara C., Wong, John K.L., Paul, Yashna, Ioannou, Nikolaos, Öztürk, Selcen, Mack, Norman, Kalter, Verena, Colomer, Dolors, Campo, Elías, Bloehdorn, Johannes, Stilgenbauer, Stephan, Dietrich, Sascha, Schmidt, Manfred, Gabriel, Richard, Rippe, Karsten, Feuerer, Markus, Ramsay, Alan G., Lichter, Peter, Zapatka, Marc, Seiffert, Martina

“…T cell exhaustion limits anti-tumor immunity and responses to immunotherapy. Here, we explored the microenvironmental signals regulating T cell exhaustion…”
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Role of surface antibody in hepatitis B reactivation in patients with resolved infection and hematologic malignancy: A meta‐analysis by Paul, Sonali, Dickstein, Aaron, Saxena, Akriti, Terrin, Norma, Viveiros, Kathleen, Balk, Ethan M., Wong, John B.

“…Patients with resolved hepatitis B virus (HBV) infection who are treated for hematological malignancies remain at risk for HBV reactivation. Because of…”
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Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement by Davidson, Karina W, Barry, Michael J, Mangione, Carol M, Cabana, Michael, Chelmow, David, Coker, Tumaini Rucker, Davis, Esa M, Donahue, Katrina E, Jaén, Carlos Roberto, Krist, Alex H, Kubik, Martha, Li, Li, Ogedegbe, Gbenga, Pbert, Lori, Ruiz, John M, Stevermer, James, Tseng, Chien-Wen, Wong, John B

“…IMPORTANCE: Cardiovascular disease (CVD) is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. Each year, an estimated 605 000…”
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The landscape of chromothripsis across adult cancer types by Voronina, Natalia, Wong, John K. L., Hübschmann, Daniel, Hlevnjak, Mario, Uhrig, Sebastian, Heilig, Christoph E., Horak, Peter, Kreutzfeldt, Simon, Mock, Andreas, Stenzinger, Albrecht, Hutter, Barbara, Fröhlich, Martina, Brors, Benedikt, Jahn, Arne, Klink, Barbara, Gieldon, Laura, Sieverling, Lina, Feuerbach, Lars, Chudasama, Priya, Beck, Katja, Kroiss, Matthias, Heining, Christoph, Möhrmann, Lino, Fischer, Andrea, Schröck, Evelin, Glimm, Hanno, Zapatka, Marc, Lichter, Peter, Fröhling, Stefan, Ernst, Aurélie

“…Chromothripsis is a recently identified mutational phenomenon, by which a presumably single catastrophic event generates extensive genomic rearrangements of…”
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Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement by Mangione, Carol M., Barry, Michael J., Nicholson, Wanda K., Cabana, Michael, Chelmow, David, Coker, Tumaini Rucker, Davis, Esa M., Donahue, Katrina E., Jaén, Carlos Roberto, Kubik, Martha, Li, Li, Ogedegbe, Gbenga, Pbert, Lori, Ruiz, John M., Stevermer, James, Wong, John B.

“…Importance Cardiovascular disease (CVD) is the leading cause of morbidity and death in the US and is the cause of more than 1 of every 4 deaths. Coronary heart…”
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Hepatitis C Guidance 2018 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection by Chung, Raymond T, Ghany, Marc G, Kim, Arthur Y, Marks, Kristen M, Naggie, Susanna, Vargas, Hugo E, Aronsohn, Andrew I, Bhattacharya, Debika, Broder, Tina, Falade-Nwulia, Oluwaseun O, Fontana, Robert J, Gordon, Stuart C, Heller, Theo, Holmberg, Scott D, Jhaveri, Ravi, Jonas, Maureen M, Kiser, Jennifer J, Linas, Benjamin P, Lo Re, Vincent, Morgan, Timothy R, Nahass, Ronald G, Peters, Marion G, Reddy, K Rajender, Reynolds, Andrew, Scott, John D, Searson, Gloria, Swan, Tracy, Terrault, Norah A, Trooskin, Stacey B, Wong, John B, Workowski, Kimberly A

“…Abstract Recognizing the importance of timely guidance regarding the rapidly evolving field of hepatitis C management, the American Association for the Study…”
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Association of mutation signature effectuating processes with mutation hotspots in driver genes and non-coding regions by Wong, John K. L., Aichmüller, Christian, Schulze, Markus, Hlevnjak, Mario, Elgaafary, Shaymaa, Lichter, Peter, Zapatka, Marc

“…Cancer driving mutations are difficult to identify especially in the non-coding part of the genome. Here, we present sigDriver, an algorithm dedicated to call…”
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