Search Results - "WOLFS, Tim G. A. M"

Time Dependent Changes in the Ovine Neurovascular Unit; A Potential Neuroprotective Role of Annexin A1 in Neonatal Hypoxic-Ischemic Encephalopathy by Park, Hyun Young, van Bruggen, Valéry L E, Peutz-Kootstra, Carine J, Ophelders, Daan R M G, Jellema, Reint K, Reutelingsperger, Chris P M, Rutten, Bart P F, Wolfs, Tim G A M

“…Perinatal brain injury following hypoxia-ischemia (HI) is characterized by high mortality rates and long-term disabilities. Previously, we demonstrated that…”
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Enteral Feeding Interventions in the Prevention of Necrotizing Enterocolitis: A Systematic Review of Experimental and Clinical Studies by de Lange, Ilse H, van Gorp, Charlotte, Eeftinck Schattenkerk, Laurens D, van Gemert, Wim G, Derikx, Joep P M, Wolfs, Tim G A M

“…Necrotizing enterocolitis (NEC), which is characterized by severe intestinal inflammation and in advanced stages necrosis, is a gastrointestinal emergency in…”
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Prematurity, perinatal inflammatory stress, and the predisposition to develop chronic kidney disease beyond oligonephropathy by Hoogenboom, Lieke A., Wolfs, Tim G. A. M., Hütten, Matthias C., Peutz-Kootstra, Carine J., Schreuder, Michiel F.

“…Prematurity and perinatal stress, such as intrauterine growth restriction (IUGR) and chorioamnionitis, are pathological processes creating an impaired…”
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Endotoxin induced chorioamnionitis prevents intestinal development during gestation in fetal sheep by Wolfs, Tim G A M, Buurman, Wim A, Zoer, Bea, Moonen, Rob M J, Derikx, Joep P M, Thuijls, Geertje, Villamor, Eduardo, Gantert, Markus, Garnier, Yves, Zimmermann, Luc J I, Kramer, Boris W

“…Chorioamnionitis is the most significant source of prenatal inflammation and preterm delivery. Prematurity and prenatal inflammation are associated with…”
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Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus by Gussenhoven, Ruth, Westerlaken, Rob J J, Ophelders, Daan R M G, Jobe, Alan H, Kemp, Matthew W, Kallapur, Suhas G, Zimmermann, Luc J, Sangild, Per T, Pankratova, Stanislava, Gressens, Pierre, Kramer, Boris W, Fleiss, Bobbi, Wolfs, Tim G A M

“…Antenatal infection (i.e., chorioamnionitis) is an important risk factor for adverse neurodevelopmental outcomes after preterm birth. Destructive and…”
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Antenatal Ureaplasma Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies by van Gorp, Charlotte, de Lange, Ilse H, Hütten, Matthias C, López-Iglesias, Carmen, Massy, Kimberly R I, Kessels, Lilian, Knoops, Kèvin, Cuijpers, Iris, Sthijns, Mireille M J P E, Troost, Freddy J, van Gemert, Wim G, Spiller, Owen B, Birchenough, George M H, Zimmermann, Luc J I, Wolfs, Tim G A M

“…Chorioamnionitis is a risk factor for necrotizing enterocolitis (NEC). (UP) is clinically the most isolated microorganism in chorioamnionitis, but its…”
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Hypoxia-Driven Changes in a Human Intestinal Organoid Model and the Protective Effects of Hydrolyzed Whey by de Lange, Ilse H, van Gorp, Charlotte, Massy, Kimberly R I, Kessels, Lilian, Kloosterboer, Nico, Bjørnshave, Ann, Stampe Ostenfeld, Marie, Damoiseaux, Jan G M C, Derikx, Joep P M, van Gemert, Wim G, Wolfs, Tim G A M

“…Many whey proteins, peptides and protein-derived amino acids have been suggested to improve gut health through their anti-oxidant, anti-microbial,…”
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Chorioamnionitis induces hepatic inflammation and time-dependent changes of the enterohepatic circulation in the ovine fetus by Heymans, Cathelijne, den Dulk, Marcel, Lenaerts, Kaatje, Heij, Lara R., de Lange, Ilse H., Hadfoune, Mhamed, van Heugten, Chantal, Kramer, Boris W., Jobe, Alan H., Saito, Masatoshi, Kemp, Matthew W., Wolfs, Tim G. A. M., van Gemert, Wim G.

“…Chorioamnionitis, inflammation of fetal membranes, is an important cause of preterm birth and a risk factor for the development of adverse neonatal outcomes…”
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Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain by Jellema, Reint K, Ophelders, Daan R M G, Zwanenburg, Alex, Nikiforou, Maria, Delhaas, Tammo, Andriessen, Peter, Mays, Robert W, Deans, Robert, Germeraad, Wilfred T V, Wolfs, Tim G A M, Kramer, Boris W

“…Preterm infants are at risk for hypoxic-ischemic encephalopathy. No therapy exists to treat this brain injury and subsequent long-term sequelae. We have…”
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ST waveform analysis for monitoring hypoxic distress in fetal sheep after prolonged umbilical cord occlusion by Andriessen, Peter, Zwanenburg, Alex, van Laar, Judith O E H, Vullings, Rik, Hermans, Ben J M, Niemarkt, Hendrik J, Jellema, Reint K, Ophelders, Daan R M G, Wolfs, Tim G A M, Kramer, Boris W, Delhaas, Tammo

“…The inconclusive clinical results for ST-waveform analysis (STAN) in detecting fetal hypoxemia may be caused by the signal processing of the STAN-device…”
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Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide by Willems, Monique G M, Kemp, Matthew W, Fast, Laura A, Wagemaker, Nick M M, Janssen, Leon E W, Newnham, John P, Payne, Matt S, Spiller, Owen B, Kallapur, Suhas G, Jobe, Alan H, Delhaas, Tammo, Kramer, Boris W, Wolfs, Tim G A M

“…Chorioamnionitis can induce pulmonary inflammation and promote bronchopulmonary dysplasia development, distinguished by alveolar simplification and impaired…”
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Effects of intra-amniotic lipopolysaccharide and maternal betamethasone on brain inflammation in fetal sheep by Kuypers, Elke, Jellema, Reint K, Ophelders, Daan R M G, Dudink, Jeroen, Nikiforou, Maria, Wolfs, Tim G A M, Nitsos, Ilias, Pillow, J Jane, Polglase, Graeme R, Kemp, Matthew W, Saito, Masatoshi, Newnham, John P, Jobe, Alan H, Kallapur, Suhas G, Kramer, Boris W

“…Chorioamnionitis and antenatal glucocorticoids are common exposures for preterm infants and can affect the fetal brain, contributing to cognitive and motor…”
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Protection of the Ovine Fetal Gut against Ureaplasma -Induced Chorioamnionitis: A Potential Role for Plant Sterols by van Gorp, Charlotte, de Lange, Ilse H, Spiller, Owen B, Dewez, Frédéric, Cillero Pastor, Berta, Heeren, Ron M A, Kessels, Lilian, Kloosterboer, Nico, van Gemert, Wim G, Beeton, Michael L, Stock, Sarah J, Jobe, Alan H, Payne, Matthew S, Kemp, Matthew W, Zimmermann, Luc J, Kramer, Boris W, Plat, Jogchum, Wolfs, Tim G A M

“…Chorioamnionitis, clinically most frequently associated with , is linked to intestinal inflammation and subsequent gut injury. No treatment is available to…”
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Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure by Ophelders, Daan R M G, Gussenhoven, Ruth, Lammens, Martin, Küsters, Benno, Kemp, Matthew W, Newnham, John P, Payne, Matthew S, Kallapur, Suhas G, Jobe, Allan H, Zimmermann, Luc J, Kramer, Boris W, Wolfs, Tim G A M

“…Intra-amniotic Candida albicans (C. Albicans) infection is associated with preterm birth and high morbidity and mortality rates. Survivors are prone to adverse…”
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Complement Factor C5a Mediates Renal Ischemia-Reperfusion Injury Independent from Neutrophils by de Vries, Bart, Kohl, Jorg, Leclercq, Wouter K. G, Wolfs, Tim G. A. M, van Bijnen, Annemarie A. J. H. M, Heeringa, Peter, Buurman, Wim A

“…The complement system has been shown to mediate renal ischemia-reperfusion (I/R) injury. However, the contribution of complement factor C5a to I/R injury, in…”
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Ovine fetal thymus response to lipopolysaccharide-induced chorioamnionitis and antenatal corticosteroids by Kuypers, Elke, Collins, Jennifer J P, Jellema, Reint K, Wolfs, Tim G A M, Kemp, Matthew W, Nitsos, Ilias, Pillow, J Jane, Polglase, Graeme R, Newnham, John P, Germeraad, Wilfred T V, Kallapur, Suhas G, Jobe, Alan H, Kramer, Boris W

“…Chorioamnionitis is associated with preterm delivery and involution of the fetal thymus. Women at risk of preterm delivery receive antenatal corticosteroids…”
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Optimized lung expansion ventilation modulates ventilation‐induced lung injury in preterm lambs by Brokken, Tim, Hütten, Matthias C., Ophelders, Daan R. M. G., Gorp, Charlotte, Wolfs, Tim G. A. M., Wald, Martin

“…Introduction Preterm infants close to viability commonly require mechanical ventilation (MV) for respiratory distress syndrome. Despite commonly used…”
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In vitro osteogenic and in ovo angiogenic effects of a family of natural origin P2O5-free bioactive glasses by Nikody, Martyna, Kessels, Lilian, Morejón, Lizette, Schumacher, Matthias, Tim G A M Wolfs, Rademakers, Timo, Delgado, José A, Habibovic, Pamela, Moroni, Lorenzo, Balmayor, Elizabeth R

“…Bioactive glasses (BGs) belong to a group of ceramic biomaterials having numerous applications due to their excellent biocompatibility and bioactivity…”
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Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy by Martinello, Kathryn A., Meehan, Christopher, Avdic-Belltheus, Adnan, Lingam, Ingran, Ragab, Sara, Hristova, Mariya, Tann, Cally J., Peebles, Donald, Hagberg, Henrik, Wolfs, Tim G. A. M., Klein, Nigel, Tachtsidis, Ilias, Golay, Xavier, Kramer, Boris W., Fleiss, Bobbi, Gressens, Pierre, Robertson, Nicola J.

“…Co-existing infection/inflammation and birth asphyxia potentiate the risk of developing neonatal encephalopathy (NE) and adverse outcome. In a newborn piglet…”
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Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2 by Vaes, Nathalie, Schonkeren, Simone L, Rademakers, Glenn, Holland, Amy M, Koch, Alexander, Gijbels, Marion J, Keulers, Tom G, de Wit, Meike, Moonen, Laura, Van der Meer, Jaleesa R M, van den Boezem, Edith, Wolfs, Tim G A M, Threadgill, David W, Demmers, Jeroen, Fijneman, Remond J A, Jimenez, Connie R, Vanden Berghe, Pieter, Smits, Kim M, Rouschop, Kasper M A, Boesmans, Werend, Hofstra, Robert M W, Melotte, Veerle

“…The N-Myc Downstream-Regulated Gene 4 ( NDRG4 ), a prominent biomarker for colorectal cancer (CRC), is specifically expressed by enteric neurons. Considering…”
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