Search Results - "WOLFERT, Robert L"

Bladder cancer biomarker discovery using global metabolomic profiling of urine by Wittmann, Bryan M, Stirdivant, Steven M, Mitchell, Matthew W, Wulff, Jacob E, McDunn, Jonathan E, Li, Zhen, Dennis-Barrie, Aphrihl, Neri, Bruce P, Milburn, Michael V, Lotan, Yair, Wolfert, Robert L

“…Bladder cancer (BCa) is a common malignancy worldwide and has a high probability of recurrence after initial diagnosis and treatment. As a result, recurrent…”
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Biochemical differences in the mass and activity tests of lipoprotein-associated phospholipase A 2 explain the discordance in results between the two assay methods by Zhuo, Shaoqiu, Wolfert, Robert L, Yuan, Chong

“…There are two platforms for the detection of Lp-PLA in sera or plasmas: by its enzymatic activity (PLAC® activity test) and by its mass concentration (PLAC®…”
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Lipoprotein-associated phospholipase A2 is associated with atherosclerotic stroke risk: the Northern Manhattan Study by Katan, Mira, Moon, Yeseon P, Paik, Myunghee C, Wolfert, Robert L, Sacco, Ralph L, Elkind, Mitchell S V

“…Lipoprotein-associated phospholipase A2 (LpPLA2) levels are associated with stroke, though whether this extends to all populations and stroke subtypes is…”
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B7-H4 is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer by SIMON, Iris, SHAOQIU ZHUO, CORRAL, Laura, DIAMANDIS, Eleftherios P, SARNO, Mark J, WOLFERT, Robert L, KIM, Nam W

“…Using cDNA database mining strategies and real-time quantitative reverse transcription-PCR, we identified B7-H4 as a novel gene that is overexpressed in…”
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Lipoprotein-associated phospholipase A2 activity predicts cardiovascular events in high risk coronary artery disease patients by Maiolino, Giuseppe, Pedon, Luigi, Cesari, Maurizio, Frigo, Anna Chiara, Wolfert, Robert L, Barisa, Marlena, Pagliani, Leopoldo, Rossitto, Giacomo, Seccia, Teresa Maria, Zanchetta, Mario, Rossi, Gian Paolo

“…Lipoprotein-associated phospholipase A2 (Lp-PLA2) is deemed to play a role in atherosclerosis and plaque destabilization as demonstrated in animal models and…”
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Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer by Simon, Iris, Liu, Yan, Krall, Kirstin L, Urban, Nicole, Wolfert, Robert L, Kim, Nam W, McIntosh, Martin W

“…Abstract Objective Early detection through regular screening could significantly reduce mortality from ovarian cancer. Advances in biomarkers and imaging…”
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B7-H4 is over-expressed in early-stage ovarian cancer and is independent of CA125 expression by Simon, Iris, Katsaros, Dionyssios, Rigault de la Longrais, Irene, Massobrio, Marco, Scorilas, Andreas, Kim, Nam W, Sarno, Mark J, Wolfert, Robert L, Diamandis, Eleftherios P

“…Abstract Objective This study characterizes the expression of the novel biomarker B7-H4 in ovarian cancer tissue, normal ovaries, and benign ovarian tumors,…”
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A Multiparametric Panel for Ovarian Cancer Diagnosis, Prognosis, and Response to Chemotherapy by YINGYE ZHENG, KATSAROS, Dionyssios, ZIDING FENG, DIAMANDIS, Eleftherios P, SHAN, Shannon J. C, RIGAULT DE LA LONGRAIS, Irene, PORPIGLIA, Mauro, SCORILAS, Andreas, KIM, Nam W, WOLFERT, Robert L, SIMON, Iris, LIN LI

“…Purpose: Our goal was to examine a panel of 11 biochemical variables, measured in cytosolic extracts of ovarian tissues (normal, benign, and malignant) by…”
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The effect of statin therapy on lipoprotein associated phospholipase A2 levels by Albert, Michelle A., Glynn, Robert J., Wolfert, Robert L., Ridker, Paul M.

“…Lipoprotein associated phospholipase A2 (Lp-PLA2), a biomarker of oxidation and inflammation, has been associated with increased coronary heart disease (CHD)…”
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Biochemical differences in the mass and activity tests of lipoprotein-associated phospholipase A2 explain the discordance in results between the two assay methods by Zhuo, Shaoqiu, Wolfert, Robert L., Yuan, Chong

“…There are two platforms for the detection of Lp-PLA2 in sera or plasmas: by its enzymatic activity (PLAC® activity test) and by its mass concentration (PLAC®…”
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Relationship of Lipoprotein-Associated Phospholipase A2 Mass and Activity with Incident Vascular Events among Primary Prevention Patients Allocated to Placebo or to Statin Therapy: An Analysis from the JUPITER Trial by RIDKER, Paul M, MACFADYEN, Jean G, WOLFERT, Robert L, KOENIG, Wolfgang

“…Although lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) levels are associated with cardiovascular events, Lp-PLA(2) is physically linked to LDL…”
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Metabolomic signatures of aggressive prostate cancer by McDunn, Jonathan E., Li, Zhen, Adam, Klaus-Peter, Neri, Bruce P., Wolfert, Robert L., Milburn, Michael V., Lotan, Yair, Wheeler, Thomas M.

“…BACKGROUND Current diagnostic techniques have increased the detection of prostate cancer; however, these tools inadequately stratify patients to minimize…”
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Differential Effect of Hypolipidemic Drugs on Lipoprotein-Associated Phospholipase A2 by Saougos, Vasilios G, Tambaki, Afroditi P, Kalogirou, Mihalis, Kostapanos, Michael, Gazi, Irene F, Wolfert, Robert L, Elisaf, Moses, Tselepis, Alexandros D

“…OBJECTIVE—Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a predictor for incident atherosclerotic disease. We investigated the effect of 3 hypolipidemic…”
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Lipoprotein-Associated Phospholipase A2 Is an Independent Predictor of Incident Coronary Heart Disease in an Apparently Healthy Older Population : The Rancho Bernardo Study by DANIELS, Lori B, LAUGHLIN, Gail A, SARNO, Mark J, BETTENCOURT, Ricki, WOLFERT, Robert L, BARRETT-CONNOR, Elizabeth

“…Lipoprotein-associated phospholipase A2 (Lp-PLA2) levels predict incident coronary heart disease (CHD) in adults without known CHD, independent of heart…”
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The reduction of inflammatory biomarkers by statin, fibrate, and combination therapy among diabetic patients with mixed dyslipidemia : The DIACOR (Diabetes and Combined Lipid Therapy Regimen) Study by MUHLESTEIN, Joseph B, MAY, Heidi T, JENSEN, Jonathan R, HORNE, Benjamin D, LANMAN, Richard B, LAVASANI, Farangis, WOLFERT, Robert L, PEARSON, Robert R, YANNICELLI, H. Daniel, ANDERSON, Jeffrey L

“…The primary objective was to determine the effect of statin-fibrate combination therapy on inflammatory biomarkers in patients with diabetes. Atherosclerosis…”
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Lipoprotein-Associated Phospholipase A2, a Novel Cardiovascular Inflammatory Marker, in HIV-Infected Patients by Mangili, Alexandra, Ahmad, Raabia, Wolfert, Robert L., Kuvin, Jeffrey, Polak, Joseph F., Karas, Richard H., Wanke, Christine A.

“…Background. Lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) is an emerging biomarker of cardiovascular disease. This study was conducted to describe the…”
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The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA2 by Tellis, Constantinos C., Moutzouri, Eliza, Elisaf, Moses, Wolfert, Robert L., Tselepis, Alexandros D.

“…Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a risk factor of cardiovascular disease. Plasma Lp-PLA2 is mainly associated with apolipoprotein…”
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The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA by Tellis, Constantinos C, Moutzouri, Eliza, Elisaf, Moses, Wolfert, Robert L, Tselepis, Alexandros D

“…Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a risk factor of cardiovascular disease. Plasma Lp-PLA₂ is mainly associated with apolipoprotein…”
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Enhancing the secretion of recombinant proteins by engineering N-glycosylation sites by Liu, Yan, Nguyen, Anton, Wolfert, Robert L., Zhuo, Shaoqiu

“…N‐glycosylation is important for the folding and quality control of membrane and secretory proteins. We used mutagenesis to introduce N‐glycosylation sequons…”
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Epitope binning of murine monoclonal antibodies by a multiplexed pairing assay by Miller, Paul L., Wolfert, Robert L., Diedrich, Gundo

“…We describe an assay and data evaluation technique for sorting a panel of murine monoclonal antibodies according to epitope specificities. The assay analyzes…”
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