Search Results - "WOLFERT, M. A"

Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery by DASH, P. R, READ, M. L, BARRETT, L. B, WOLFERT, M. A, SEYMOUR, L. W

“…Self-assembling polycation/DNA complexes represent a promising synthetic vector for gene delivery. However, despite considerable versatility and transfectional…”
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Best Fit for Common Purpose: A Multi-Stakeholder Design Optimization Methodology for Construction Management by Zhilyaev, Dmitry, Binnekamp, Ruud, Wolfert, A. M. Rogier

“…Within traditional design processes, decisions are often made based on individualistic values and late-stage assessments conducted on a predefined set of…”
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Sources of Escherichia coli in a Coastal Subtropical Environment by SOLO-GABRIELE, H. M, WOLFERT, M. A, DESMARAIS, T. R, PALMER, C. J

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers by Oupický, D., Koňák, Č., Ulbrich, K., Wolfert, M.A., Seymour, L.W.

“…Block and graft copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) with 2-(trimethylammonio)ethyl methacrylate were synthesised and used for preparation of…”
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Atomic force microscopic analysis of the influence of the molecular weight of poly(L)lysine on the size of polyelectrolyte complexes formed with DNA by Wolfert, M A, Seymour, L W

“…We are developing self-assembling micellar vehicles based on multifunctional block copolymers as well-defined synthetic vehicles suitable for safe in vivo…”
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Chloroquine and amphipathic peptide helices show synergistic transfection in vitro by WOLFERT, M. A, SEYMOUR, L. W

“…A pH-responsive peptide fragment modelled on the influenza virus haemagglutinin (INF7-SGSC) can promote the transfectional activity of poly(L)-lysine (pLL)/DNA…”
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Improving Subsurface Asset Failure Predictions for Utility Operators: A Unique Case Study on Cable and Pipe Failures Resulting from Excavation Work by Wijs, R. J. A, Nane, G. F, Leontaris, G, van Manen, T. R. W, Wolfert, A. R. M

“…AbstractUtility operators must rely on predictive analyses regarding the availability of their subsurface assets, which highly depend on damage by increasing…”
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Multi-system intervention optimization for interdependent infrastructure by Kammouh, Omar, Nogal, Maria, Binnekamp, Ruud, Wolfert, A.R.M. Rogier

“…The wellbeing of modern societies is dependent upon the functioning of their infrastructure networks. This paper introduces the 3C concept, an integrative…”
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Infrastructure maintenance and replacement optimization under multiple uncertainties and managerial flexibility by van den Boomen, Martine, Spaan, Matthijs T. J., Shang, Yue, Wolfert, A. R. M.

“…Infrastructure maintenance and replacement decisions are subject to uncertainties such as regular asset degradation, structural failure, and price uncertainty…”
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Synthesis and Proinflammatory Effects of Peptidoglycan-Derived Neoglycopeptide Polymers by Siriwardena, Aloysius, Jørgensen, Malene R, Wolfert, Margreet A, Vandenplas, Michel L, Moore, James N, Boons, Geert-Jan

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Replacement optimization of ageing infrastructure under differential inflation by van den Boomen, M., Leontaris, G., Wolfert, A. R. M.

“…Ageing public infrastructure assets necessitate economic replacement analysis. A common replacement problem concerns an existing asset challenged by a…”
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Untangling decision tree and real options analyses: a public infrastructure case study dealing with political decisions, structural integrity and price uncertainty by van den Boomen, M., Spaan, M. T. J., Schoenmaker, R., Wolfert, A. R. M.

“…Managerial flexibility in infrastructure investment and replacement decisions adds value. Real options analysis (ROA) captures this value under uncertain…”
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Mitigation Controller: Adaptive Simulation Approach for Planning Control Measures in Large Construction Projects by Kammouh, Omar, Nogal, Maria, Binnekamp, Ruud, Wolfert, A. R. M. (Rogier)

“…AbstractProbabilistic Monte Carlo simulations are often used to determine a project’s completion time given a required probability level. During project…”
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Extreme-oriented sensitivity analysis using sparse polynomial chaos expansion. Application to train–track–bridge systems by Shang, Yue, Nogal, Maria, Teixeira, Rui, Wolfert, A.R. (Rogier) M.

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Optimal design of rail level crossings and associated transition zones using adaptive surrogate-assisted optimization by Shang, Yue, Nogal, Maria, Teixeira, Rui, Wolfert, A.R. (Rogier) M.

“…Transition zones such as level crossing and bridge approaches are critical links in railway networks due to higher degradation rates and maintenance needs. In…”
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Polyelectrolyte Vectors for Gene Delivery:  Influence of Cationic Polymer on Biophysical Properties of Complexes Formed with DNA by Wolfert, Margreet A, Dash, Philip R, Nazarova, Ola, Oupicky, David, Seymour, Leonard W, Smart, Sarah, Strohalm, Jiri, Ulbrich, Karel

“…Cationic polymer/DNA complexes are widely used for gene delivery, although the influence of the cationic polymer on the biophysical properties of the resulting…”
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Synthesis and evaluation of poly(ethylene glycol)-polylysine block copolymers as carriers for gene delivery by VANDERKERKEN, S, VANHEEDE, T, TONCHEVA, V, SCHACHT, E, WOLFERT, M. A, SEYMOUR, L, URTTI, A

“…Different types of poly(ethylene glycol)-poly(L-lysine) PEG-PLL block copolymers were examined for their ability to form polyelectrolyte complexes with DNA,…”
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Novel vectors for gene delivery formed by self-assembly of DNA with poly( l-lysine) grafted with hydrophilic polymers by Toncheva, Veska, Wolfert, Margreet A, Dash, Philip R, Oupicky, David, Ulbrich, Karel, Seymour, Leonard W, Schacht, Etienne H

“…Complexes formed between DNA and cationic polymers are attracting increasing attention as novel synthetic vectors for delivery of genes. We are trying to…”
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Characterization of vectors for gene therapy formed by self-assembly of DNA with synthetic block co-polymers by Wolfert, M A, Schacht, E H, Toncheva, V, Ulbrich, K, Nazarova, O, Seymour, L W

“…Cationic polymers can self-assemble with DNA to form polyelectrolyte complexes capable of gene delivery, although biocompatibility of the complexes is…”
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Synthesis and Evaluation of Poly(Ethylene Glycol)-Polylysine Block Copolymers as Carriers for Gene Delivery by Vanderkerken, S., Vanheede, T., Toncheva, V., Schacht, E., Wolfert, M. A., Seymour, L., Urtti, A.

“…Different types of poly(ethylene glycol)-poly(l-lysine) PEG-PLL block copolymers were examined for their ability to form polyelectrolyte complexes with DNA,…”
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