Search Results - "WOLF, H"
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Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology
Published in Bioinformatics (15-07-2019)“…Abstract Motivation The composition and density of immune cells in the tumor microenvironment (TME) profoundly influence tumor progression and success of…”
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The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies
Published in Frontiers in immunology (07-05-2020)“…Tumor cells constantly interact with their microenvironment, which comprises a variety of immune cells together with endothelial cells and fibroblasts. The…”
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B cells and tertiary lymphoid structures as determinants of tumour immune contexture and clinical outcome
Published in Nature reviews. Clinical oncology (01-07-2022)“…B cells are a major component of the tumour microenvironment, where they are predominantly associated with tertiary lymphoid structures (TLS). In germinal…”
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4
Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression
Published in Genome Biology (20-10-2016)“…We introduce the Microenvironment Cell Populations-counter (MCP-counter) method, which allows the robust quantification of the absolute abundance of eight…”
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Central venous catheter-related infections in hematology and oncology: 2012 updated guidelines on diagnosis, management and prevention by the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology
Published in Annals of oncology (01-05-2014)“…Cancer patients are at increased risk for central venous catheter-related infections (CRIs). Thus, a comprehensive, practical and evidence-based guideline on…”
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6
Protein quality control and elimination of protein waste: the role of the ubiquitin-proteasome system
Published in Biochimica et biophysica acta (01-01-2014)“…Mistakes are part of our world and constantly occurring. Due to transcriptional and translational failures, genomic mutations or diverse stress conditions like…”
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7
The non-autonomous retrotransposon SVA is trans-mobilized by the human LINE-1 protein machinery
Published in Nucleic acids research (01-02-2012)“…SINE-VNTR-Alu (SVA) elements are non-autonomous, hominid-specific non-LTR retrotransposons and distinguished by their organization as composite mobile…”
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The immune contexture in cancer prognosis and treatment
Published in Nature reviews. Clinical oncology (01-12-2017)“…Key Points Most cancers have evaded immune control, or immunosurveillance, at the time of presentation; however, residual signs of an active anticancer immune…”
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The tumor microenvironment: Prognostic and theranostic impact. Recent advances and trends
Published in Seminars in immunology (01-04-2020)Get full text
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Intraoperative Hypotension Is Associated With Adverse Clinical Outcomes After Noncardiac Surgery
Published in Anesthesia and analgesia (01-06-2021)“…BACKGROUND:Intraoperative hypotension (IOH) occurs frequently during surgery and may be associated with organ ischemia; however, few multicenter studies report…”
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Tertiary lymphoid structures and B cells: An intratumoral immunity cycle
Published in Immunity (Cambridge, Mass.) (10-10-2023)“…The generation of anti-tumor immunity in the draining lymph nodes is known as the cancer immunity cycle. Accumulating evidence supports the occurrence of such…”
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Protein Quality Control of the Endoplasmic Reticulum and Ubiquitin-Proteasome-Triggered Degradation of Aberrant Proteins: Yeast Pioneers the Path
Published in Annual review of biochemistry (20-06-2018)“…Cells must constantly monitor the integrity of their macromolecular constituents. Proteins are the most versatile class of macromolecules but are sensitive to…”
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Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer
Published in Clinical cancer research (01-07-2015)“…Clear cell renal cell carcinoma (ccRCC) has shown durable responses to checkpoint blockade therapies. However, important gaps persist in the understanding of…”
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Therapeutic Targeting of the Colorectal Tumor Stroma
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2020)“…Colorectal tumors have been classified based on histologic factors, genetic factors, and consensus molecular subtypes, all of which affect the tumor…”
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Ten‐year update of the international registry on cytokine‐induced killer cells in cancer immunotherapy
Published in Journal of cellular physiology (01-12-2020)“…Cytokine‐induced killer (CIK) cells represent an exceptional T‐cell population uniting a T cell and natural killer cell‐like phenotype in their terminally…”
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The Cdc48 machine in endoplasmic reticulum associated protein degradation
Published in Biochimica et biophysica acta (01-01-2012)“…The AAA-type ATPase Cdc48 (named p97/VCP in mammals) is a molecular machine in all eukaryotic cells that transforms ATP hydrolysis into mechanic power to…”
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Benchmarking of participant-level confound regression strategies for the control of motion artifact in studies of functional connectivity
Published in NeuroImage (Orlando, Fla.) (01-07-2017)“…Since initial reports regarding the impact of motion artifact on measures of functional connectivity, there has been a proliferation of participant-level…”
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Age-Related Effects and Sex Differences in Gray Matter Density, Volume, Mass, and Cortical Thickness from Childhood to Young Adulthood
Published in The Journal of neuroscience (17-05-2017)“…Developmental structural neuroimaging studies in humans have long described decreases in gray matter volume (GMV) and cortical thickness (CT) during…”
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Primary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)
Published in Annals of hematology (01-02-2018)“…Immunocompromised patients are at high risk of invasive fungal infections (IFI), in particular those with haematological malignancies undergoing…”
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Health Care Costs Associated With Incident Complications in Patients With Type 2 Diabetes in Germany
Published in Diabetes care (01-05-2018)“…The aim of this study is to provide reliable regression-based estimates of costs associated with different type 2 diabetes complications. We used nationwide…”
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