Search Results - "WOJTA, Johann"

Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells by Puhm, Florian, Afonyushkin, Taras, Resch, Ulrike, Obermayer, Georg, Rohde, Manfred, Penz, Thomas, Schuster, Michael, Wagner, Gabriel, Rendeiro, Andre F., Melki, Imene, Kaun, Christoph, Wojta, Johann, Bock, Christoph, Jilma, Bernd, Mackman, Nigel, Boilard, Eric, Binder, Christoph J.

“…RATIONALE:Extracellular vesicles, including microvesicles, are increasingly recognized as important mediators in cardiovascular disease. The cargo and surface…”
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The Paradigm Change of IL-33 in Vascular Biology by Demyanets, Svitlana, Stojkovic, Stefan, Huber, Kurt, Wojta, Johann

“…In this review, we focus on the actual understanding of the role of IL-33 in vascular biology in the context of the historical development since the…”
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Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart by Davidson, Sean M, Padró, Teresa, Bollini, Sveva, Vilahur, Gemma, Duncker, Dirk J, Evans, Paul C, Guzik, Tomasz, Hoefer, Imo E, Waltenberger, Johannes, Wojta, Johann, Weber, Christian

“…Abstract We review some of the important discoveries and advances made in basic and translational cardiac research in 2020. For example, in the field of…”
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Antithrombotic therapy and body mass: an expert position paper of the ESC Working Group on Thrombosis by Rocca, Bianca, Fox, Keith A A, Ajjan, Ramzi A, Andreotti, Felicita, Baigent, Colin, Collet, Jean-Philippe, Grove, Erik L, Halvorsen, Sigrun, Huber, Kurt, Morais, João, Patrono, Carlo, Rubboli, Andrea, Seljeflot, Ingebjorg, Sibbing, Dirk, Siegbahn, Agneta, Ten Berg, Jurrien, Vilahur, Gemma, Verheugt, Freek W A, Wallentin, Lars, Weiss, Thomas W, Wojta, Johann, Storey, Robert F

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Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature by Demyanets, Svitlana, Kaun, Christoph, Pentz, Richard, Krychtiuk, Konstantin A, Rauscher, Sabine, Pfaffenberger, Stefan, Zuckermann, Andreas, Aliabadi, Arezu, Gröger, Marion, Maurer, Gerald, Huber, Kurt, Wojta, Johann

“…Abstract Interleukin-33 (IL-33) is a recently described member of the IL-1 family of cytokines, which was identified as a ligand for the ST2 receptor…”
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MicroRNAs as Regulators and Biomarkers of Platelet Function and Activity in Coronary Artery Disease by Stojkovic, Stefan, Nossent, Anne Yaël, Haller, Paul, Jäger, Bernhard, Vargas, Kris G, Wojta, Johann, Huber, Kurt

“…Microribonucleic acids (miRs) are small, noncoding ribonucleic acids (RNAs), which play an important role in the regulation of platelet function and activity…”
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Soluble ST2 in Patients with Carotid Artery Stenosis-Association with Plaque Morphology and Long-Term Outcome by Stojkovic, Stefan, Kampf, Stephanie, Harkot, Olesya, Nackenhorst, Maja, Brekalo, Mira, Huber, Kurt, Hengstenberg, Christian, Neumayer, Christoph, Wojta, Johann, Demyanets, Svitlana

“…Interleukin (IL-33) and the ST2 receptor are implicated in the pathogenesis of atherosclerosis. Soluble ST2 (sST2), which negatively regulates IL-33 signaling,…”
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Soluble ST2 as a Potential Biomarker for Abdominal Aortic Aneurysms-A Single-Center Retrospective Cohort Study by Klopf, Johannes, Demyanets, Svitlana, Brekalo, Mira, Eilenberg, Wolf, Wojta, Johann, Neumayer, Christoph, Brostjan, Christine, Stojkovic, Stefan

“…The maximal aortic diameter is the only clinically applied predictor of abdominal aortic aneurysm (AAA) progression and indicator for surgical repair…”
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Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology by Eschenhagen, Thomas, Force, Thomas, Ewer, Michael S., de Keulenaer, Gilles W., Suter, Thomas M., Anker, Stefan D., Avkiran, Metin, de Azambuja, Evandro, Balligand, Jean-Luc, Brutsaert, Dirk L., Condorelli, Gianluigi, Hansen, Arne, Heymans, Stephane, Hill, Joseph A., Hirsch, Emilio, Hilfiker-Kleiner, Denise, Janssens, Stefan, de Jong, Steven, Neubauer, Gitte, Pieske, Burkert, Ponikowski, Piotr, Pirmohamed, Munir, Rauchhaus, Mathias, Sawyer, Douglas, Sugden, Peter H., Wojta, Johann, Zannad, Faiez, Shah, Ajay M.

“…The reductions in mortality and morbidity being achieved among cancer patients with current therapies represent a major achievement. However, given their…”
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Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation by Stojkovic, Stefan, Kaun, Christoph, Basilio, Jose, Rauscher, Sabine, Hell, Lena, Krychtiuk, Konstantin A., Bonstingl, Cornelia, de Martin, Rainer, Gröger, Marion, Ay, Cihan, Holnthoner, Wolfgang, Eppel, Wolfgang, Neumayer, Christoph, Huk, Ihor, Huber, Kurt, Demyanets, Svitlana, Wojta, Johann

“…Tissue factor (TF) is the primary trigger of coagulation. Elevated levels of TF are found in atherosclerotic plaques and TF leads to thrombus formation when…”
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Lipoprotein(a) plasma levels are not associated with survival after acute coronary syndromes: An observational cohort study by Roth, Christian, Krychtiuk, Konstantin A, Gangl, Clemens, Schrutka, Lore, Distelmaier, Klaus, Wojta, Johann, Hengstenberg, Christian, Berger, Rudolf, Speidl, Walter S

“…Lipoprotein(a) [Lp(a)] is associated with coronary artery disease in population studies, however studies on its predictive value in patients with…”
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Circulatory miR-411-5p as a Novel Prognostic Biomarker for Major Adverse Cardiovascular Events in Patients with Atrial Fibrillation by Nopp, Stephan, van der Bent, M Leontien, Kraemmer, Daniel, Königsbrügge, Oliver, Wojta, Johann, Pabinger, Ingrid, Ay, Cihan, Nossent, Anne Yaël

“…The risk stratification of patients with atrial fibrillation (AF) for subsequent cardiovascular events could help in guiding prevention strategies. In this…”
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Tenascin-C promotes chronic pressure overload-induced cardiac dysfunction, hypertrophy and myocardial fibrosis by Podesser, Bruno K, Kreibich, Maximilian, Dzilic, Elda, Santer, David, Förster, Lorenz, Trojanek, Sandra, Abraham, Dietmar, Krššák, Martin, Klein, Klaus U, Tretter, Eva V, Kaun, Christoph, Wojta, Johann, Kapeller, Barbara, Gonçalves, Inês Fonseca, Trescher, Karola, Kiss, Attila

“…AIMS:Left ventricular (LV) hypertrophy is characterized by cardiomyocyte hypertrophy and interstitial fibrosis ultimately leading to increased myocardial…”
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Soluble ST2 and interleukin-33 levels in coronary artery disease: relation to disease activity and adverse outcome by Demyanets, Svitlana, Speidl, Walter S, Tentzeris, Ioannis, Jarai, Rudolf, Katsaros, Katharina M, Farhan, Serdar, Krychtiuk, Konstantin A, Wonnerth, Anna, Weiss, Thomas W, Huber, Kurt, Wojta, Johann

“…ST2 is a receptor for interleukin (IL)-33. We investigated an association of soluble ST2 (sST2) and IL-33 serum levels with different clinical stages of…”
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Interleukin-33 Induces Expression of Adhesion Molecules and Inflammatory Activation in Human Endothelial Cells and in Human Atherosclerotic Plaques by Demyanets, Svitlana, Konya, Viktoria, Kastl, Stefan P, Kaun, Christoph, Rauscher, Sabine, Niessner, Alexander, Pentz, Richard, Pfaffenberger, Stefan, Rychli, Kathrin, Lemberger, Christof E, de Martin, Rainer, Heinemann, Akos, Huk, Ihor, Gröger, Marion, Maurer, Gerald, Huber, Kurt, Wojta, Johann

“…OBJECTIVE—Interleukin (IL)-33 is the most recently described member of the IL-1 family of cytokines and it is a ligand of the ST2 receptor. While the effects…”
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Alternative activation of human macrophages enhances tissue factor expression and production of extracellular vesicles by Hohensinner, Philipp J, Mayer, Julia, Kichbacher, Julia, Kral-Pointner, Julia, Thaler, Barbara, Kaun, Christoph, Hell, Lena, Haider, Patrick, Mussbacher, Marion, Schmid, Johannes A, Stojkovic, Stefan, Demyanets, Svitlana, Fischer, Michael B, Huber, Kurt, Wöran, Katharina, Hengstenberg, Christian, Speidl, Walter S, Oehler, Rudolf, Pabinger, Ingrid, Wojta, Johann

“…Macrophages are versatile cells that can be polarized by the tissue environment to fulfill required needs. Proinflammatory polarization is associated with…”
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Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in human cardiovascular disease by Håkansson, Kjell E J, Goossens, Eveline A C, Trompet, Stella, van Ingen, Eva, de Vries, Margreet R, van der Kwast, Reginald V C T, Ripa, Rasmus S, Kastrup, Jens, Hohensinner, Philipp J, Kaun, Christoph, Wojta, Johann, Böhringer, Stefan, Le Cessie, Saskia, Jukema, J Wouter, Quax, Paul H A, Nossent, A Yaël

“…Abstract Aims We have shown that 14q32 microRNAs are highly involved in vascular remodelling and cardiovascular disease. However, the 14q32 locus also encodes…”
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The adipokine vaspin is associated with decreased coronary in-stent restenosis in vivo and inhibits migration of human coronary smooth muscle cells in vitro by Kastl, Stefan P, Katsaros, Katharina M, Krychtiuk, Konstantin A, Jägersberger, Gerlinde, Kaun, Christoph, Huber, Kurt, Wojta, Johann, Speidl, Walter S

“…Percutaneous coronary intervention represents the most important treatment modality of coronary artery stenosis. In-stent restenosis (ISR) is still a…”
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The role of platelets in athero-thrombotic events by Freynhofer, Matthias K, Bruno, Veronika, Wojta, Johann, Huber, Kurt

“…The crucial role of platelets in primary hemostasis and repair of injured endothelium is well established, as is their role in atherothrombosis. No other…”
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Quantitative and Functional Assessment of the Influence of Routinely Used Cryopreservation Media on Mononuclear Leukocytes for Medical Research by Haider, Patrick, Hoberstorfer, Timothy, Salzmann, Manuel, Fischer, Michael B, Speidl, Walter S, Wojta, Johann, Hohensinner, Philipp J

“…Quantitative and functional analysis of mononuclear leukocyte populations is an invaluable tool to understand the role of the immune system in the pathogenesis…”
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