Search Results - "WOHLRAB, Johannes"

Expression and activity of IL-17 receptor subunits in human cutaneous cells as targets for anti-IL-17 therapeutic antibodies by Wohlrab, Johannes, Gerloff, Dennis, Gebhardt, Kathleen

“…The key players in different chronic inflammatory skin diseases are cytokines belonging to the IL-17 group, IL-17 receptors and a T helper cell population,…”
Get full text

Discussion of EMA Draft Guideline on Quality and Equivalence of Topical Products Based on Comparison of Approved Mometasone Furoate Drugs by Eichner, Adina, Mrestani, Yahya, Hukauf, Martin, Wohlrab, Johannes

“…Introduction Today, the approval for a generic topical product includes the presentation of therapeutic equivalence to the originator based on clinical trials…”
Get full text

Potential Applications of Phyto-Derived Ceramides in Improving Epidermal Barrier Function by Tessema, Efrem N, Gebre-Mariam, Tsige, Neubert, Reinhard H H, Wohlrab, Johannes

“…The outer most layer of the skin, the stratum corneum, consists of corneocytes which are coated by a cornified envelope and embedded in a lipid matrix of…”
Get more information

Hyperhidrosis: A Central Nervous Dysfunction of Sweat Secretion by Wohlrab, Johannes, Bechara, Falk G., Schick, Christoph, Naumann, Markus

“…Hyperhidrosis (HH) is a central nervous dysfunction characterized by abnormally increased sweating due to a central dysregulation of sweat secretion. HH…”
Get full text

Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells by Udelnow, Andrej, Kreyes, Andreas, Ellinger, Stefan, Landfester, Katharina, Walther, Paul, Klapperstueck, Thomas, Wohlrab, Johannes, Henne-Bruns, Doris, Knippschild, Uwe, Würl, Peter

“…Omeprazole has recently been described as a modulator of tumour chemoresistance, although its underlying molecular mechanisms remain controversial. Since…”
Get full text

Does human leukocyte elastase degrade intact skin elastin? by Schmelzer, Christian E. H., Jung, Michael C., Wohlrab, Johannes, Neubert, Reinhard H. H., Heinz, Andrea

“…This study aimed to investigate the susceptibility of intact fibrillar human elastin to human leukocyte elastase and cathepsin G. Elastin is a vital protein of…”
Get full text

Etoricoxib-induced toxic epidermal necrolysis: Successful treatment with infliximab by KREFT, Burkhard, WOHLRAB, Johannes, BRAMSIEPE, Isa, EISMANN, Regina, WINKLER, Matthias, MARSCH, Wolfgang Christian

Get full text

Treatment of a Clinically Relevant Plant-Pathogenic Fungus with an Agricultural Azole Causes Cross-Resistance to Medical Azoles and Potentiates Caspofungin Efficacy by Serfling, Albrecht, Wohlrab, Johannes, Deising, Holger B

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Methodological aspects of measuring absolute values of membrane potential in human cells by flow cytometry by Klapperstück, Thomas, Glanz, Dagobert, Klapperstück, Manuela, Wohlrab, Johannes

“…The bis-barbituric acid oxonol, DiBAC₄(3) is used as a standard potentiometric probe in human cells. However, its fluorescence depends not only on membrane…”
Get full text

Influence of keratolytics on cutaneous pharmacokinetics of glucocorticoids by Wohlrab, Johannes

“…Summary Background: Keratolytics are often used to accelerate and improve the therapeutic response of hyperkeratotic dermatoses. Keratolytics are a chemically…”
Get full text

Profiling of human stratum corneum ceramides by means of normal phase LC/APCI-MS by Farwanah, Hany, Wohlrab, Johannes, Neubert, Reinhard H. H, Raith, Klaus

“…The ceramides of the stratum corneum are critical to maintaining the epidermal barrier function of the skin. A number of skin diseases and disorders are known…”
Get full text

Ceramide profiles of the uninvolved skin in atopic dermatitis and psoriasis are comparable to those of healthy skin by FARWANAH, Hany, RAITH, Klaus, NEUBERT, Reinhard H. H, WOHLRAB, Johannes

“…Ceramides are sphingolipids consisting of sphingoidbases, which are amide-linked to fatty acids. In the stratum corneum, they represent the major constituent…”
Get full text

Pharmacology of inhibitors of Janus kinases – Part 1: Pharmacokinetics by Eichner, Adina, Wohlrab, Johannes

“…Summary The use of Janus kinase inhibitors for the treatment of chronic inflammatory diseases is increasingly establishing itself as a treatment option for…”
Get full text

Einfluss von Keratolytika auf die kutane Pharmakokinetik von Glukokortikoiden by Wohlrab, Johannes

Get full text

Characterization of cationic amino acid transporters (hCATs) 1 and 2 in human skin by Jaeger, Kristin, Paulsen, Friedrich, Wohlrab, Johannes

“…In the present study, we characterized the distribution of human cationic amino acid transporters 1 (hCAT1) and 2 (hCAT2) in healthy skin and compared it to…”
Get full text

Topical preparations and their use in dermatology by Wohlrab, Johannes

“…Summary The challenges of everyday clinical routine require dermatologists to have a basic knowledge of the composition of topical preparations as well as the…”
Get full text

Persistent erythema and edema of the midthird and upper aspect of the face (morbus morbihan): Evidence of hidden immunologic contact urticaria and impaired lymphatic drainage by Wohlrab, Johannes, Lueftl, Matthias, Marsch, Wolfgang C.

“…A persistent erythema and edema of the midthird and upper aspect of the face, which bears some resemblance to Melkersson-Rosenthal syndrome and rosaceous…”
Get full text

Niacinamide - mechanisms of action and its topical use in dermatology by Wohlrab, Johannes, Kreft, Daniela

“…Niacinamide, an amide of vitamin B3 (niacin), is a hydrophilic endogenous substance. Its effects after epicutaneous application have long been described in the…”
Get more information

Pharmakologie der Januskinase-Inhibitoren - Teil 2: Pharmakodynamik: Pharmacology of inhibitors of Janus kinases - Part 2: Pharmacodynamics by Eichner, Adina, Wohlrab, Johannes

“…Als niedermolekulare Substanzen haben die Januskinase-Inhibitoren unterschiedliche, dosisabhängige pharmakologische Bindungsselektivitäten, die allerdings…”
Get full text

Pharmacology of inhibitors of Janus kinases – Part 2: Pharmacodynamics by Eichner, Adina, Wohlrab, Johannes

“…Summary As small molecules, the Janus kinase inhibitors have different, dose‐dependent pharmacological binding selectivities, which, however, do not allow…”
Get full text