Search Results - "WITTEKINDT, O"
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Benzimidazolones enhance the function of epithelial Na+ transport
Published in British journal of pharmacology (01-03-2013)“…Background and Purpose Pharmacological enhancement of vectorial Na+ transport may be useful to increase alveolar fluid clearance. Herein, we investigated the…”
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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat : a candidate for schizophrenia and bipolar disorder?
Published in Molecular psychiatry (1998)“…Many human hereditary neurodegenerative diseases are caused by expanded CAG repeats, and anonymous CAG expansions have also been described in schizophrenia and…”
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The cardiac K+ channel KCNQ1 is essential for gastric acid secretion
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2001)“…Background & Aims: Gastric H+ secretion via the H+/K+-adenosine triphosphatase is coupled to the uptake of K+. However, the molecular identity of luminal K+…”
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Mutation screening of the KCNN3 gene reveals a rare frameshift mutation
Published in Molecular psychiatry (01-05-2001)Get full text
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A 24-Ch. Multi-Electrode Array Allowing Fast EIS to Determine Transepithelial Electrical Resistance
Published in 2019 IEEE Biomedical Circuits and Systems Conference (BioCAS) (01-10-2019)“…Electrochemical Impedance Spectroscopy (EIS) is a standard method to investigate properties of biological samples due to its non-invasiveness. Multi-electrode…”
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Conference Proceeding -
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C73 NEW MECHANISMS AND THERAPIES IN COPD: Effect Of Interleukin 13 On Human Tracheal Epithelial Cells
Published in American journal of respiratory and critical care medicine (01-01-2017)“…Corresponding author's email: oliver.wittekindt@uni-ulm.de Interleukin 13 (IL-13) plays a pivotal role in exacerbating inflammatory lung diseases such as COPD…”
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Association between hSKCa3 and schizophrenia not confirmed by transmission disequilibrium test in 193 offspring/parents trios
Published in Molecular psychiatry (01-05-1999)“…A possible association between the small conductance calcium-regulated potassium channel gene, hSKCa3, and schizophrenia has recently been described by Chandy…”
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Stable methylation patterns in interspecific antelope hybrids and the characterization and localization of a satellite fraction in the Alcelaphini and Hippotragini
Published in Chromosome research (01-10-2000)“…Conflicting data has recently appeared concerning altered methylation patterns in interspecific mammalian hybrids and the potential this may hold for driving…”
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The human small conductance calcium-regulated potassium channel gene (hSKCa3) contains two CAG repeats in exon 1, is on chromosome 1q21.3, and shows a possible association with schizophrenia
Published in Neurogenetics (01-08-1998)“…Mutations in various ion channel genes are responsible for neuromuscular and other neurological disorders. We have previously identified the human small…”
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Single Silicon Nanowire SERS Probes for Highly Localized Optical pH Sensing
Published in 2018 IEEE 18th International Conference on Nanotechnology (IEEE-NANO) (01-07-2018)“…The field of Surface Enhanced Raman Spectroscopy (SERS) was under intense research in the past few decades. Although the basic principles and fundamentals of…”
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Conference Proceeding -
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Atomic force microscopy of microvillous cell surface dynamics at fixed and living alveolar type II cells
Published in Analytical and bioanalytical chemistry (01-03-2011)“…Scanning probe techniques enable direct imaging of morphology changes associated with cellular processes at life specimen. Here, glutaraldehyde-fixed and…”
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An apamin- and scyllatoxin-insensitive isoform of the human SK3 channel
Published in Molecular pharmacology (01-03-2004)“…We have isolated an hSK3 isoform from a human embryonic cDNA library that we have named hSK3_ex4. This isoform contains a 15 amino acid insertion within the S5…”
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The human Ca2+-activated K+ channel, IK, can be blocked by the tricyclic antihistamine promethazine
Published in Neuropharmacology (01-03-2006)“…Phenothiazines can be used as psychopharmaceutical agents and are known to cause many side effects during treatment since they interfere with many different…”
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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: A candidate for schizophrenia and bipolar disorder?
Published in Molecular psychiatry (01-01-1997)“…Many human hereditary neurodegenerative diseases are caused by expanded CAG repeats, and anonymous CAG expansions have also been described in schizophrenia and…”
Get full text
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A novel non-neuronal hSK3 isoform with a dominant-negative effect on hSK3 currents
Published in Cellular physiology and biochemistry (01-01-2004)“…We have identified a hSK3-transcript, hSK3_ex1c, which is generated by alternative splicing. Isoform hSK3_ex1c lacks the cytosolic N-terminus and the first…”
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