Search Results - "WITT, Tyra A"

Characterization of a Resident Population of Adventitial Macrophage Progenitor Cells in Postnatal Vasculature by Psaltis, Peter J, Puranik, Amrutesh S, Spoon, Daniel B, Chue, Colin D, Hoffman, Scott J, Witt, Tyra A, Delacroix, Sinny, Kleppe, Laurel S, Mueske, Cheryl S, Pan, Shuchong, Gulati, Rajiv, Simari, Robert D

“…RATIONALE:Macrophages regulate blood vessel structure and function in health and disease. The origins of tissue macrophages are diverse, with evidence for…”
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Pulmonary Biodistribution of Platelet-Derived Regenerative Exosomes in a Porcine Model by Rizzo, Skylar A, Bagwell, Monique S, Schiebel, Paige, Rolland, Tyler J, Mahlberg, Ryan C, Witt, Tyra A, Nagel, Mary E, Stalboerger, Paul G, Behfar, Atta

“…The purpose of this study was to evaluate the biodistribution of a platelet-derived exosome product (PEP), previously shown to promote regeneration in the…”
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Low-Dose Gamma Irradiation of Decellularized Heart Valves Results in Tissue Injury In Vitro and In Vivo by Helder, Meghana R.K., MD, Hennessy, Ryan S., MD, Spoon, Daniel B., MD, Tefft, Brandon J., PhD, Witt, Tyra A., CVT, Marler, Ronald J., DVM, PhD, Pislaru, Sorin V., MD, PhD, Simari, Robert D., MD, Stulak, John M., MD, Lerman, Amir, MD

“…Background Decellularized heart valves are emerging as a potential alternative to current bioprostheses for valve replacement. Whereas techniques of…”
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Identification of a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Adventitia of Postnatal Murine Aorta by PSALTIS, Peter J, HARBUZARIU, Adriana, GULATI, Rajiv, SANDHU, Gurpreet S, SIMARI, Robert D, DELACROIX, Sinny, WITT, Tyra A, HOLROYD, Eric W, SPOON, Daniel B, HOFFMAN, Scott J, SHUCHONG PAN, KLEPPE, Laurel S, MUESKE, Cheryl S

“…Hematopoiesis originates from the dorsal aorta during embryogenesis. Although adult blood vessels harbor progenitor populations for endothelial and smooth…”
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Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence by Rolland, Tyler J., Peterson, Timothy E., Singh, Raman Deep, Rizzo, Skylar A., Boroumand, Soulmaz, Shi, Ao, Witt, Tyra A., Nagel, Mary, Kisby, Cassandra K., Park, Sungjo, Rowe, Lois A., Paradise, Christopher R., Becher, Laura R. E., Paradise, Brooke D., Stalboerger, Paul G., Trabuco, Emanuel C., Behfar, Atta

“…Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these…”
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Autologous culture-modified mononuclear cells confer vascular protection after arterial injury by GULATI, Rajiv, JEVREMOVIC, Dragan, PETERSON, Timothy E, WITT, Tyra A, KLEPPE, Laurel S, MUESKE, Cheryl S, LERMAN, Amir, VILE, Richard G, SIMARI, Robert D

“…Bone marrow-derived cells have been shown to contribute to endothelial replacement after vascular injury. In vitro culture of peripheral blood mononuclear…”
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Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate by Pan, Shuchong, Chen, Horng H, Correia, Cristina, Dai, Haiming, Witt, Tyra A, Kleppe, Laurel S, Burnett, Jr, John C, Simari, Robert D

“…The family of natriuretic peptides (NPs), including atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and C-type natriuretic peptide (CNP),…”
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Author Correction: Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence by Rolland, Tyler J., Peterson, Timothy E., Singh, Raman Deep, Rizzo, Skylar A., Boroumand, Soulmaz, Shi, Ao, Witt, Tyra A., Nagel, Mary, Kisby, Cassandra K., Park, Sungjo, Rowe, Lois A., Paradise, Christopher R., Becher, Laura R. E., Paradise, Brooke D., Stalboerger, Paul G., Trabuco, Emanuel C., Behfar, Atta

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Tissue Factor Pathway Inhibitor Blocks Angiogenesis via Its Carboxyl Terminus by Holroyd, Eric W, Delacroix, Sinny, Larsen, Katarina, Harbuzariu, Adriana, Psaltis, Peter J, Wang, Ling, Pan, Shuchong, White, Thomas A, Witt, Tyra A, Kleppe, Laurel S, Mueske, Cheryl S, Mukhopadhyay, Debabrata, Simari, Robert D

“…OBJECTIVE—Tissue factor pathway inhibitor (TFPI) is the primary regulator of the tissue factor (TF) coagulation pathway. As such, TFPI may regulate the…”
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Vascular-Directed Tissue Factor Pathway Inhibitor Overexpression Regulates Plasma Cholesterol and Reduces Atherosclerotic Plaque Development by Pan, Shuchong, White, Thomas A, Witt, Tyra A, Chiriac, Anca, Mueske, Cheri S, Simari, Robert D

“…RATIONALE:Tissue factor pathway inhibitor (TFPI) is a potent regulator of the tissue factor pathway and is found in plasma in association with lipoproteins…”
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Modulation of the vascular response to injury by autologous blood-derived outgrowth endothelial cells by Gulati, Rajiv, Jevremovic, Dragan, Witt, Tyra A, Kleppe, Laurel S, Vile, Richard G, Lerman, Amir, Simari, Robert D

“…Delivery of a heterogeneous population of cells with endothelial phenotype derived from peripheral blood has been shown to improve vascular responses after…”
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Vasoprotective effects of human CD34+ cells: towards clinical applications by Kiernan, Thomas J, Boilson, Barry A, Witt, Tyra A, Dietz, Allan B, Lerman, Amir, Simari, Robert D

“…The development of cell-based therapeutics for humans requires preclinical testing in animal models. The use of autologous animal products fails to address the…”
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[89Zr]Zr-DBN labeled cardiopoietic stem cells proficient for heart failure by Bansal, Aditya, Pandey, Mukesh K., Yamada, Satsuki, Goyal, Ribu, Schmit, Nicholas R., Jeon, Ryounghoon, Nesbitt, Jonathan J., Witt, Tyra A., Singh, Raman D., Gunderson, Tina M., Boroumand, Soulmaz, Li, Mark, Crespo-Diaz, Ruben J., Hillestad, Matthew L., Terzic, Andre, Behfar, Atta, DeGrado, Timothy R.

“…Radiolabeling of stem cells with a positron emitting radioisotope represents a major advancement in regenerative biotherapy enabling non-invasive imaging. To…”
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Vasculogenic properties of adventitial Sca-1+CD45+ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis by Toledo-Flores, Deborah, Williamson, Anna, Schwarz, Nisha, Fernando, Sanuja, Dimasi, Catherine, Witt, Tyra A., Nguyen, Thao M., Puranik, Amrutesh S., Chue, Colin D., Delacroix, Sinny, Spoon, Daniel B., Bonder, Claudine S., Bursill, Christina A., Di Bartolo, Belinda A., Nicholls, Stephen J., Simari, Robert D., Psaltis, Peter J.

“…The cellular origins of vasa vasorum are ill-defined and may involve circulating or local progenitor cells. We previously discovered that murine aortic…”
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Nanoparticle-Mediated Cell Capture Enables Rapid Endothelialization of a Novel Bare Metal Stent by Tefft, Brandon J, Uthamaraj, Susheil, Harbuzariu, Adriana, Harburn, J Jonathan, Witt, Tyra A, Newman, Brant, Psaltis, Peter J, Hlinomaz, Ota, Holmes, Jr, David R, Gulati, Rajiv, Simari, Robert D, Dragomir-Daescu, Dan, Sandhu, Gurpreet S

“…Incomplete endothelialization of intracoronary stents has been associated with stent thrombosis and recurrent symptoms, whereas prolonged use of dual…”
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M 3 RNA Drives Targeted Gene Delivery in Acute Myocardial Infarction by Singh, Raman Deep, Hillestad, Matthew L, Livia, Christopher, Li, Mark, Alekseev, Alexey E, Witt, Tyra A, Stalboerger, Paul G, Yamada, Satsuki, Terzic, Andre, Behfar, Atta

“…The M RNA (microencapsulated modified messenger RNA) platform is an approach to deliver messenger RNA (mRNA) in vivo, achieving a nonintegrating and viral-free…”
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Intravascular Delivery of Biologics to the Rat Kidney by Franchi, Federico, Zhu, Xiang Yang, Witt, Tyra A, Lerman, Lilach O, Rodriguez-Porcel, Martin

“…The renal microvascular compartment plays an important role in the progression of kidney disease and hypertension, leading to the development of End Stage…”
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Tissue factor pathway inhibitor overexpression inhibits hypoxia-induced pulmonary hypertension by White, Thomas A, Witt, Tyra A, Pan, Shuchong, Mueske, Cheryl S, Kleppe, Laurel S, Holroyd, Eric W, Champion, Hunter C, Simari, Robert D

“…Pulmonary hypertension (PH) is a commonly recognized complication of chronic respiratory disease. Enhanced vasoconstriction, pulmonary vascular remodeling, and…”
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Murine strain differences in hemostasis and thrombosis and tissue factor pathway inhibitor by White, Thomas A, Pan, Shuchong, Witt, Tyra A, Simari, Robert D

“…Abstract Introduction Differences among murine strains often lead to differential responses in models of human disease. The aim of the current study was to…”
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The effect of vascular smooth muscle cell-targeted expression of tissue factor pathway inhibitor in a murine model of arterial thrombosis by Pan, Shuchong, Kleppe, Laurel S, Witt, Tyra A, Mueske, Cheryl S, Simari, Robert D

“…Tissue factor pathway inhibitor (TFPI) is a Kunitz-type protease inhibitor that regulates the extrinsic pathway of coagulation by inhibiting the factor…”
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