Search Results - "WITT, Richard C"

Overexpression of 5-Lipoxygenase in Colon Polyps and Cancer and the Effect of 5-LOX Inhibitors In vitro and in a Murine Model by MELSTROM, Laleh G, BENTREM, David J, BELL, Richard H, ADRIAN, Thomas A, SALABAT, Mohammad R, KENNEDY, Timothy J, DING, Xian-Zhong, STROUCH, Matthew, RAO, Sambasiva M, WITT, Richard C, TERNENT, Charles A, TALAMONTI, Mark S

“…Purpose: Arachidonic acid metabolism via the cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) pathways modulates cell growth and apoptosis. Many studies have…”
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Leukotriene B4 Receptor Antagonist LY293111 Inhibits Proliferation and Induces Apoptosis in Human Pancreatic Cancer Cells by TONG, Wei-Gang, DING, Xian-Zhong, HENNIG, Rene, WITT, Richard C, STANDOP, Jens, POUR, Parviz M, ADRIAN, Thomas E

“…Purpose: The effects of leukotriene (LT) B4 and its receptorantagonist LY293111 on proliferation and apoptosis of human pancreatic cancer cells were…”
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Lipoxygenase inhibitors attenuate growth of human pancreatic cancer xenografts and induce apoptosis through the mitochondrial pathway by Tong, Wei-Gang, Ding, Xian-Zhong, Witt, Richard C, Adrian, Thomas E

“…Several studies have suggested that high dietary fat intake, particularly essential fatty acids, is associated with pancreatic cancer development and growth…”
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Differential effects of calpain inhibitors on hypertrophy of cardiomyocytes by Pollack, Jay R, Witt, Richard C, Sugimoto, Jeffrey T

“…Two inhibitors of the calcium-dependent cysteine protease, calpain, have markedly different effects on the extent of hypertrophy induced by the…”
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Effect of LY293111 in combination with gemcitabine in colonic cancer by Hennig, Rene, Ding, Xian-Zhong, Tong, Wei-Gang, Witt, Richard C, Jovanovic, Borko D, Adrian, Thomas E

“…New adjuvant therapies are needed for the treatment of stage III colon cancer. The essential fatty acids, linoleic and arachidonic acid enhance tumorigenesis…”
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Factors Associated with Participation in Hiv Antibody Screening and Results Disclosure by Silvestre, Anthony J., Kingsley, Lawrence A., Rinaldo, Charles, Witt, Richard C., Lyter, David W., Valdiserri, Ronald

“…The Centers for Disease Control reported in October 1991 that many people at risk for human immunodeficiency virus (HIV) infection had not been tested for…”
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Guidelines for disclosing HIV-antibody test results to clients by Witt, R C, Silvestre, A J, Rinaldo, Jr, C R, Lyter, D W

“…Because of new preventive therapies, HIV-antibody testing of asymptomatic individuals now has clear clinical benefits. Consequently, greater numbers of…”
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Effects of calpain inhibitors on phenylephrine-induced hypertrophy of cardiomyocytes by Pollack, Jay R., Witt, Richard C., Sugimoto, Jeffrey T.

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Lipoxygenase Inhibitors Attenuate Growth of Human Pancreatic Cancer Xenografts and Induce Apoptosis through the Mitochondrial Pathway 1 This study was supported by grants from National Cancer Institute SPORE Program Grant P50 CA72712, Lustgarten Foundation for Pancreatic Cancer Research Grant LF47, and American Institute for Cancer Research Grant 00B065. 1 by Wei-Gang Tong, Xian-Zhong Ding, Richard C. Witt, Thomas E. Adrian

“…Several studies have suggested that high dietary fat intake, particularly essential fatty acids, is associated with pancreatic cancer development and growth…”
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Acidosis masks β-adrenergic control of cardiac L-type calcium current by Rozanski, George J., Witt, Richard C.

“…The β-adrenergic control of the L-type Ca 2∗ current (I ca) was examined as a function of extracellular pH (pH o) in guinea-pig ventricular myocytes using the…”
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The effects of selected lichen extracts and purified compounds on the rat heart by Witt, Richard C

“…Extracts from Letharia vulpina, Umbilicaria americana, Cladina subtenuis, Xanthoparmelia cumberlandia, Rimelia reticulata, and Parmotrema austrosinense were…”
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Early afterdepolarizations and triggered activity in rabbit cardiac Purkinje fibers recovering from ischemic-like conditions : role of acidosis by ROZANSKI, G. J, WITT, R. C

“…The mechanisms underlying repetitive activity during reperfusion of ischemic myocardium are thought to include triggered responses elicited at short pacing…”
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Alterations in repolarization of cardiac Purkinje fibers recovering from ischemic-like conditions: genesis of early afterdepolarizations by Rozanski, G J, Witt, R C

“…Triggered activity initiated from delayed after-depolarizations has been proposed as a possible cause of arrhythmias during reperfusion of ischemic myocardium…”
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Effects of flecainide on ectopic atrial automaticity and conduction by WINDLE, J. R, WITT, R. C, ROZANSKI, G. J

“…Previous studies have shown that class Ic antiarrhythmic agents are effective in suppressing ectopic atrial rhythms and accessory pathway conduction. To…”
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Electrophysiologic effects of exogenous phosphocreatine in cardiac tissue: potential antiarrhythmic actions by Rosenshtraukh, L V, Witt, R C, Nance, P N, Rozanski, G J

“…The cellular electrophysiologic effects of exogenous phosphocreatine (PCr) were analyzed to ascertain its purported antiarrhythmic properties during myocardial…”
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