Search Results - "WISNIESKI, J. J"

The Globular Heads of C1q Specifically Recognize Surface Blebs of Apoptotic Vascular Endothelial Cells by Navratil, Jeannine S, Watkins, Simon C, Wisnieski, Jeffrey J, Ahearn, Joseph M

“…Complement protein C1q is required to maintain immune tolerance. The molecular mechanism responsible for this link has not been determined. We have previously…”
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Urticarial vasculitis by Wisnieski, Jeffrey J

“…Chronic or recurrent urticarial lesions are common in both primary care and referral medicine. Diagnosis and treatment are usually a challenge for both the…”
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Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus by Racila, D M, Sontheimer, C J, Sheffield, A, Wisnieski, J J, Racila, E, Sontheimer, R D

“…We report an association between a non-familial form of photosensitive Lupus-specific skin disease, subacute cutaneous lupus erythematosus (SCLE), and a new…”
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Comparison of autoantibodies to the collagen-like region of C1q in hypocomplementemic urticarial vasculitis syndrome and systemic lupus erythematosus by Wisnieski, JJ, Jones, SM

“…Hypocomplementemic urticarial vasculitis syndrome (HUVS) is an apparent autoimmune disorder that resembles SLE. We previously showed that C1q precipitins in…”
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Antibodies to C1q in systemic lupus erythematosus: Characteristics and relation to FcγRIIA alleles by Haseley, Leah A., Wisnieski, Jeffrey J., Denburg, Michelle R., Michael-Grossman, Abigail R., Ginzler, Ellen M., Gourley, Mark F., Hoffman, Jean H., Kimberly, Robert P., Salmon, Jane E.

“…Antibodies to C1q in systemic lupus erythematosus: Characteristics and relation to FcγRIIA alleles. Autoantibodies to the collagen-like region of the first…”
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Metabolic and Microbial Responses to Exercise in C57 Wild-type and Adenylyl Cyclase 5 KO Mice: 943 Board #204 May 30 2: 00 PM - 3: 30 PM by Dowden, Robert A., Wisnieski, Paul J., Guers, John, Oydanich, Macro, Vatner, Stephen F., McGuinness, Lora, Kerkhof, Lee, Campbell, Sara

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Characterization of a Cloned Temperature-Sensitive Construct of the Diphtheria Toxin A Domain by Lee, Jason W, Cho, Eun, Aghaian, Elda, Aghaian, Elsa, Der, Joshua, Wisnieski, Bernadine J

“…Our goal was to determine how the DTM mutant construct of the A domain of diphtheria toxin (DTx) causes temperature-sensitive effects in Drosophila and yeast…”
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C1 Inhibitor: Analysis of the Role of Amino Acid Residues Within the Reactive Center Loop in Target Protease Recognition by Zahedi, Rana, MacFarlane, Ryan C, Wisnieski, Jeffrey J, Davis, Alvin E., III

“…Previous analysis of a naturally occurring C1 inhibitor P2 mutant (Ala(443)-->Val) indicated a role for P2 in specificity determination. To define this role…”
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Formation of Ion-Permeable Channels by Tumor Necrosis Factor-α by Kagan, Bruce L., Baldwin, Rae Lynn, Munoz, David, Wisnieski, Bernadine J.

“…Tumor necrosis factor-α (TNF, cachectin), a protein secreted by activated macrophages, participates in inflammatory responses and in infectious and neoplastic…”
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Structural Changes of Tumor Necrosis Factor α Associated with Membrane Insertion and Channel Formation by Baldwin, Rae Lynn, Stolowitz, Mark L., Hood, Leroy, Wisnieski, Bernadine J.

“…Low pH enhances tumor necrosis factor α (TNF)-induced cytolysis of cancer cells and TNF-membrane interactions that include binding, insertion, and ion-channel…”
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IgG autoantibody to the collagen-like region of Clq in hypocomplementemic urticarial vasculitis syndrome, systemic lupus erythematosus, and 6 other musculoskeletal or rheumatic diseases by Wisnieski, J J, Jones, S M

“…We previously found that the Clq precipitin in sera from patients with hypocomplementemic urticarial vasculitis syndrome is an IgG autoantibody to Clq. We…”
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Hypocomplementemic urticarial vasculitis syndrome with severe systemic manifestations by Martini, Alberto, Ravelli, Angelo, Albani, Salvatore, De Benedetti, Fabrizio, Massa, Margherita, Wisnieski, Jeffrey J.

“…We describe two children with clinical and laboratory features of hypocomplementemic urticarial vasculitis syndrome. Both patients had severe, life-threatening…”
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Mechanistic aspects of the deoxyribonuclease activity of diphtheria toxin by Lee, Jason W., Nakamura, Lawrence T., Chang, Michael P., Wisnieski, Bernadine J.

“…Here we examined the intrinsic nuclease activity of diphtheria toxin (DTx) to determine the mechanism by which it catalyzes DNA degradation. Results show that…”
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Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition by CHANG, M. P, BRAMHALL, J, GRAVES, S, BONAVIDA, B, WISNIESKI, B. J

“…Diphtheria toxin (DTx) is an extremely potent inhibitor of protein synthesis. Cell death has been generally accepted as a straightforward effect of translation…”
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The clinical spectrum of the arthropathy associated with hidradenitis suppurativa and acne conglobata by Rosner, I A, Burg, C G, Wisnieski, J J, Schacter, B Z, Richter, D E

“…Patients with hidradenitis suppurativa/acne conglobata attending a university medical center were evaluated for the presence of an associated arthritis. Of 44…”
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Induction of monocyte expression of tumor necrosis factor alpha by the 30-kD alpha antigen of Mycobacterium tuberculosis and synergism with fibronectin by Aung, H, Toossi, Z, Wisnieski, J J, Wallis, R S, Culp, L A, Phillips, N B, Phillips, M, Averill, L E, Daniel, T M, Ellner, J J

“…Native 30-kD antigen, also known as alpha antigen, is a fibronectin-binding protein that is secreted by live Mycobacterium tuberculosis. This antigen may play…”
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IgG autoantibodies to complement C1q in pediatric-onset systemic lupus erythematosus by Ravelli, A, Wisnieski, J J, Ramenghi, B, Ballardini, G, Zonta, L, Martini, A

“…Antibodies to C1q (aC1q) have been found in up to 50% of adult patients with systemic lupus erythematosus (SLE) and have been associated with proliferative…”
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Autoantibodies in systemic lupus erythematosus and urticarial vasculitis by D'Cruz, D P, Wisnieski, J J, Asherson, R A, Khamashta, M A, Hughes, G R

“…Urticarial vasculitis (UV) is both a primary disorder and a cutaneous vasculitic manifestation in patients with connective tissue diseases. We examined the…”
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Renal insufficiency with monoclonal gammopathy and urticarial vasculitis by O'Hare, Ann, Olson, Jean L., Connolly, M.Kari, Ward, John W., Stein, Peter, Wisnieski, Jeffrey J., Chertow, Glenn M.

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Serum complement determinations in patients with quiescent systemic lupus erythematosus by Sullivan, K E, Wisnieski, J J, Winkelstein, J A, Louie, J, Sachs, E, Choi, R, Veksler, E, Goldman, D, Petri, M

“…To determine whether complement component analyses during a period of inactive disease can define clinically important subgroups and predict morbidity in…”
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