Search Results - "WIRTH, Gregory J"

Metformin Decreases Glucose Oxidation and Increases the Dependency of Prostate Cancer Cells on Reductive Glutamine Metabolism by FENDT, Sarah-Maria, BELL, Eric L, PATNAIK, Akash, BLOUIN, Marie Jose, CANTLEY, Lewis C, GUARENTE, Leonard, BLENIS, John, POLLAK, Michael N, OLUMI, Aria F, VANDER HEIDEN, Matthew G, STEPHANOPOULOS, Gregory, KEIBLER, Mark A, DAVIDSON, Shawn M, WIRTH, Gregory J, FISKE, Brian, MAYERS, Jared R, SCHWAB, Matthias, BELLINGER, Gary, CSIBI, Alfredo

“…Metformin inhibits cancer cell proliferation, and epidemiology studies suggest an association with increased survival in patients with cancer taking metformin;…”
Get full text

A novel nomogram provides improved accuracy for predicting biochemical recurrence after radical prostatectomy by Xia, Hai-Zhui, Bi, Hai, Yan, Ye, Yang, Bin, Ma, Ruo-Zhuo, He, Wei, Zhu, Xue-Hua, Zhang, Zhi-Ying, Zhang, Yu-Ting, Ma, Lu-Lin, Hou, Xiao-Fei, Wirth, Gregory J., Lu, Jian

“…Abstract Background: Various prediction tools have been developed to predict biochemical recurrence (BCR) after radical prostatectomy (RP); however, few of the…”
Get full text

The effect of HER2 status on oncological outcomes of patients with invasive bladder cancer by Soria, Francesco, MD, Moschini, Marco, MD, Haitel, Andrea, MD, Wirth, Gregory J., MD, Gust, Kilian M., MD, Briganti, Alberto, MD, Rouprêt, Morgan, M.D., Ph.D, Klatte, Tobias, M.D, Hassler, Melanie R., Ph.D, Karakiewicz, Pierre I., M.D, Shariat, Shahrokh F., Ph.D

“…Abstract Purpose The aim of this study was to evaluate the overexpression of human epidermal growth factor receptor 2 (HER2) in patients with bladder cancer…”
Get full text

Impact of Multifocality and Multilocation of Positive Surgical Margin After Radical Prostatectomy on Predicting Oncological Outcome by Wu, Shulin, Lin, Sharron X., Wirth, Gregory J., Lu, Min, Lu, Jian, Subtelny, Alexander O., Wang, Zongwei, Dahl, Douglas M., Olumi, Aria F., Wu, Chin-Lee

“…To assess the impact of focality and location of positive surgical margins (PSM) on long-term outcomes after radical prostatectomy (RP) for prostate cancer…”
Get full text

Bulbomembranous anastomotic urethroplasty for strictures of the proximal bulbar urethra unassociated with pelvic trauma by Fenner, Vanessa, Benamran, Daniel A, Tran, Sao‐Nam, Venzi, Giordano, Wirth, Gregory J, Iselin, Christophe E

Get full text

Preoperative anemia is associated with disease recurrence and progression in patients with non–muscle-invasive bladder cancer by Soria, Francesco, M.D, Moschini, Marco, M.D, Abufaraj, Mohammad, M.D, Wirth, Gregory J., M.D, Foerster, Beat, M.D, Gust, Kilian M., M.D, Özsoy, Mehmet, M.D, Briganti, Alberto, M.D, Gontero, Paolo, M.D, Mathieu, Romain, M.D, Rouprêt, Morgan, M.D, Karakiewicz, Pierre I., M.D, Shariat, Shahrokh F., M.D

“…Abstract Purpose To evaluate the effect of preoperative anemia (PA) on oncological outcomes in a multicenter cohort of patients with non–muscle-invasive…”
Get full text

Prostatic Utricle Cyst as the Most Likely Cause in a Case of Recurrent Episodes of Hematospermia by Montet, Xavier, Wirth, Gregory J., De Perrot, Thomas, Feutry, Grégoire, Martin, S. P.

“…Hematospermia is a clinical symptom that raises anxiety in patients and has various causes, benign and malignant. We report a case of hematospermia for which…”
Get full text

80-W GreenLight Laser Vaporization Versus Transurethral Resection of the Prostate for Treatment of Benign Prostatic Obstruction: 5-Year Outcomes of a Single-center Prospective Randomized Trial by Mordasini, Livio, Di Bona, Carlo, Klein, Jacques, Mattei, Agostino, Wirth, Gregory J., Iselin, Christophe E.

“…To assess long term functional and safety follow-up data after 80-W GreenLight photoselective vaporization (GL PV) of the prostate and transurethral resection…”
Get full text

Quantification of perineural invasion focus after radical prostatectomy could improve predictive power of recurrence by Wu, Shulin, Xie, Ling, Lin, Sharron X., Wirth, Gregory J., Lu, Min, Zhang, Yifen, Blute, Michael L., Dahl, Douglas M., Wu, Chin-Lee

“…Perineural invasion (PNI) after radical prostatectomy (RP) is a common feature of prostate cancer (PCa) and has been associated with unfavorable tumor…”
Get full text

Post-kidney Transplant Robot-assisted Laparoscopic Ureteral (Donor-receiver) Anastomosis for Kidney Graft Reflux or Stricture Disease by Benamran, Daniel A., Klein, Jacques, Hadaya, Karine, Wirth, Gregory J., Martin, Pierre-Yves, Iselin, Christophe E.

“…To report our experience with robot-assisted ureteral anastomosis for kidney graft. Kidney graft complex ureteral strictures or symptomatic vesicoureteral…”
Get full text

Tissue Microarrays of Human Tumor Xenografts: Characterization of Proteins Involved in Migration and Angiogenesis for Applications in the Development of Targeted Anticancer Agents by Smith, Victoria, Wirth, Gregory J, Fiebig, Heinz-Herbert, Burger, Angelika M

“…As new target-directed anticancer agents emerge, preclinical efficacy studies need to integrate target-driven model systems. This approach to drug development…”
Get full text

Advances in the management of blunt traumatic bladder rupture: experience with 36 cases by Wirth, Gregory J., Peter, Robin, Poletti, Pierre‐Alexandre, Iselin, Christophe E.

“…Study Type – Therapy (case series)
Level of Evidence 4 OBJECTIVE To assess how advances in urology, radiology and orthopaedics are changing the current…”
Get full text

Validation of preoperative risk grouping of the selection of patients most likely to benefit from neoadjuvant chemotherapy before radical cystectomy by Moschini, Marco, Soria, Francesco, Klatte, Tobias, Wirth, Gregory, Özsoy, Mehmet, Gust, Killian, Briganti, Alberto, Roupret, Morgan, Susani, Martin, Haitel, Andrea, Shariat, Shahrokh F

“…Abstract Introduction To validate the value of preoperative patient characteristics in prognosticating survival after radical cystectomy (RC) to guide…”
Get full text

Characterization of Late Recurrence after Radical Cystectomy in a Large Multicenter Cohort of Bladder Cancer Patients by Soria, Francesco, Moschini, Marco, Wirth, Gregory J, Gust, Kilian M, Klatte, Tobias, Briganti, Alberto, Gontero, Paolo, Abufaraj, Mohammad, Özsoy, Mehmet, Karakiewicz, Pierre I, Shariat, Shahrokh F

“…Abstract Objective To investigate the characteristics and outcomes of late recurrence (LR) in bladder cancer (BCa) patients treated with radical cystectomy…”
Get full text

HER2 overexpression is associated with worse outcomes in patients with upper tract urothelial carcinoma (UTUC) by Soria, Francesco, Moschini, Marco, Haitel, Andrea, Wirth, Gregory J., Karam, Jose A., Wood, Christopher G., Rouprêt, Morgan, Margulis, Vitaly, Karakiewicz, Pierre I., Briganti, Alberto, Raman, Jay D., Kammerer-Jacquet, Solene-Florence, Mathieu, Romain, Bensalah, Karim, Lotan, Yair, Özsoy, Mehmet, Remzi, Mesut, Gust, Kilian M., Shariat, Shahrokh F.

“…Purpose The aim of our study was to evaluate the expression pattern of HER2 overexpression in patients with upper tract urothelial carcinoma (UTUC) and to…”
Get full text

Long-term Oncologic Impact of Positive Anterior and Posterior Surgical Margins After Radical Prostatectomy by Wu, Shulin, Lin, Sharron X., Wirth, Gregory J., Lu, Min, Lu, Jian, Subtelny, Alexander O., Wang, Zongwei, Olumi, Aria F., Dahl, Douglas M., Blute, Michael L., Wu, Chin-Lee

“…The objective of this study was to evaluate the impact of the anterior/posterior status of positive surgical margin (PSM) on long-term outcomes after radical…”
Get full text

A close surgical margin after radical prostatectomy is an independent predictor of recurrence by Lu, Jian, Wirth, Gregory J, Wu, Shulin, Chen, Junxing, Dahl, Douglas M, Olumi, Aria F, Young, Robert H, McDougal, W Scott, Wu, Chin-Lee

“…The term close surgical margin refers to a tumor extending to the inked margin of the specimen without reaching it. Current guidelines state that a close…”
Get more information

A Phase 1/2 Single-arm Clinical Trial of Recombinant Bacillus Calmette-Guérin (BCG) VPM1002BC Immunotherapy in Non–muscle-invasive Bladder Cancer Recurrence After Conventional BCG Therapy: SAKK 06/14 by Rentsch, Cyrill A., Thalmann, George N., Lucca, Ilaria, Kwiatkowski, Maciej, Wirth, Grégory J., Strebel, Räto T., Engeler, Daniel, Pedrazzini, Augusto, Hüttenbrink, Clemens, Schultze-Seemann, Wolfgang, Torpai, Raimund, Bubendorf, Lukas, Wicki, Andreas, Roth, Beat, Bosshard, Piet, Püschel, Heike, Boll, Daniel T., Hefermehl, Lukas, Roghmann, Florian, Gierth, Michael, Ribi, Karin, Schäfer, Simon, Hayoz, Stefanie

“…Intravesical therapy with the recombinant bacillus Calmette-Guérin (BCG) strain VPM1102BC is safe and well tolerated and maintains quality of life in 70% of…”
Get full text

Transrectal Ultrasound-Guided Prostate Biopsy for Cancer Detection: Performance of 2D-, 3D- and 3D-MRI Fusion Targeted Techniques by Klein, Jacques, de Górski, Arachk, Benamran, Daniel, Vallee, Jean-Paul, De Perrot, Thomas, Wirth, Gregory J, Iselin, Christophe E

“…The study aimed to evaluate 3 different modalities of transrectal ultrasound (TRUS)-guided prostate biopsies (PBs; 2D-, 3D- and targeted 3D-TRUS with fusion to…”
Get more information

Midterm oncological outcomes of laparoscopic vs open radical prostatectomy (RP) by Wirth, Gregory J., Psutka, Sarah P., Chapin, Brian F., Wu, Shulin, Wu, Chin‐Lee, Dahl, Douglas M.

“…Objective To compare the midterm risks of biochemical recurrence (BCR) and salvage radiation therapy (SRT) after laparoscopic (LRP) and open retropubic radical…”
Get full text