Search Results - "WIRKNER, K"
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Sniffin’ Sticks Screening 12 test: Presentation of odours on filter paper improves the recognition rate
Published in Rhinology (01-01-2021)“…To the Editor: Monitoring of olfactory function and diagnosis of olfactory disorders using the pen-based “Sniffin' Sticks test” is problematic during the…”
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Prevalence and risk factors of smell dysfunction - a comparison between five German population-based studies
Published in Rhinology (01-04-2020)“…The prevalence of olfactory impairment increases with age and is known to be an early sign of different neurodegenerative diseases. Only few population-based…”
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Metabotropic P2Y receptors inhibit P2X 3 receptor‐channels via G protein‐dependent facilitation of their desensitization
Published in British journal of pharmacology (29-01-2009)“…Background and purpose: The aim of the present study was to investigate whether the endogenous metabotropic P2Y receptors modulate ionotropic P2X 3…”
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Co-transmitter function of ATP in central catecholaminergic neurons of the rat
Published in Neuroscience (01-01-2001)“…Intracellular recordings were made in a mid-pontine slice preparation of the rat brain containing the nucleus locus coeruleus. Focal electrical stimulation…”
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Inhibition of N-Type Voltage-Activated Calcium Channels in Rat Dorsal Root Ganglion Neurons by P2Y Receptors Is a Possible Mechanism of ADP-Induced Analgesia
Published in The Journal of neuroscience (28-01-2004)“…Patch-clamp recordings from small-diameter rat dorsal root ganglion (DRG) neurons maintained in culture demonstrated preferential inhibition by ATP of…”
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Effect of adenosine and some of its structural analogues on the conductance of NMDA receptor channels in a subset of rat neostriatal neurones
Published in British journal of pharmacology (01-09-1997)“…1 In order to investigate the modulatory effects of adenosine on excitatory amino acid projections onto striatal medium spiny neurones, whole‐cell patch clamp…”
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Modulation of ionotropic glutamate receptor channels
Published in Neurochemical research (01-09-2001)“…Glutamate is the major excitatory neurotransmitter in the brain. It acts at ligand-gated cationic channels (NMDA, AMPA and kainate receptors) and at G…”
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Ethanol-induced inhibition of NMDA receptor channels
Published in Neurochemistry international (01-08-1999)“…Ethanol is a potent inhibitor of the N-methyl- d-aspartate (NMDA)-receptor subtype of glutamate receptor in a number of brain areas. The mechanism of ethanol…”
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Mechanism of inhibition by ethanol of NMDA and AMPA receptor channel functions in cultured rat cortical neurons
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-12-2000)“…The effect and mode of action of ethanol on N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors of rat…”
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Neuroreceptors and Ion Channels as Targets of Alcohol
Published in Alcoholism, clinical and experimental research (01-05-2001)“…This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Toshio Narahashi and Kinya Kuriyama. The…”
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Journal Article Conference Proceeding -
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The monomers of the P2X1 receptor model and KcsA protein share a similar structural fold
Published in Protein and peptide letters (2006)“…There is evidence that the P2X1 receptor subunit is involved in apoptosis, platelet aggregation, and smooth muscle contraction. The conformation of the…”
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P2X2, P2X2–2 and P2X5 receptor subunit expression and function in rat thoracolumbar sympathetic neurons
Published in Journal of neurochemistry (01-11-2001)“…The present study investigated the pharmacological properties of excitatory P2X receptors and P2X2 and P2X5 receptor subunit expression in rat‐cultured…”
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P2X7 receptors in the nervous system
Published in Progress in neurobiology (01-04-2006)“…P2X(7) receptors are ligand-gated ion channels, expressed as homo-oligomeric assemblies of individual subunits. They are widely distributed at immunocompetent…”
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Subsensitivity of P2X but not vanilloid 1 receptors in dorsal root ganglia of rats caused by cyclophosphamide cystitis
Published in European journal of pharmacology (01-08-2003)“…The application of cyclophosphamide to rats was used to induce interstitial cystitis. Behavioural studies indicated a strong pain reaction that developed…”
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Reference ranges for the Elecsys® IGF-1 and IGFBP-3 immunoassays: Effects of age, gender and pubertal stage
Published in Clinica chimica acta (01-06-2019)Get full text
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HBM4EU feasibility studies: Lessons learned in combining health and human biomonitoring studies
Published in European journal of public health (21-10-2022)“…Background The European Human Biomonitoring Initiative (HBM4EU) is a program protecting humans from the health effects of chemicals. The goal of HBM4EU is to…”
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Effect of Long-Term Ethanol Pretreatment on the Metabolism of Dichloromethane to Carbon Monoxide in Rats
Published in Toxicology and applied pharmacology (01-03-1997)“…The present study investigates the influence of long-term ethanol (ETOH) treatment of rats [10% (v/v) for 4, 12, and 36 weeks] on the metabolism of DCM after…”
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Renal function and lipid metabolism are major predictors of circumpapillary retinal nerve fiber layer thickness-the LIFE-Adult Study
Published in BMC medicine (07-09-2021)“…Circumpapillary retinal nerve fiber layer thickness (cpRNFLT) as assessed by spectral domain optical coherence tomography (SD-OCT) is a new technique used for…”
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Single-cell RT-PCR analysis of N-methyl-D-aspartate receptor subunit expression in rat locus coeruleus neurones
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-01-2001)“…Whole-cell patch-clamp recordings were performed on 12- to 15-day-old rat locus coeruleus neurones in a midpontine slice preparation. Application of…”
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