Search Results - "WINTROUB, B. U"

A systematic review of the safety of topical therapies for atopic dermatitis by Callen, J., Chamlin, S., Eichenfield, L.F., Ellis, C., Girardi, M., Goldfarb, M., Hanifin, J., Lee, P., Margolis, D., Paller, A.S., Piacquadio, D., Peterson, W., Kaulback, K., Fennerty, M., Wintroub, B.U.

“…Summary Background  The safety of topical therapies for atopic dermatitis (AD), a common and morbid disease, has recently been the focus of increased scrutiny,…”
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Human mast cell carboxypeptidase. Selective localization to MCTC cells by Irani, AM, Goldstein, SM, Wintroub, BU, Bradford, T, Schwartz, LB

“…Two murine mAb were prepared against human mast cell carboxypeptidase (HMC-CP) purified from human skin, and were termed CP1 and CP2, respectively. Double…”
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The fibrinogenolytic activity of purified tryptase from human lung mast cells by Schwartz, LB, Bradford, TR, Littman, BH, Wintroub, BU

“…The capacity of purified tryptase from human lung mast cells to metabolize human fibrinogen, fibrin, and plasminogen was evaluated. Tryptase (5 micrograms/ml)…”
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Human mast cell carboxypeptidase: purification and characterization by GOLDSTEIN, S. M, KAEMPFER, C. E, KEALEY, J. T, WINTROUB, B. U

“…A carboxypeptidase activity was recently identified in highly purified human lung mast cells and dispersed mast cells from skin. Using affinity chromatography…”
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Lamellar Body-Enriched Fractions from Neonatal Mice: Preparative Techniques and Partial Characterization by Grayson, Stephen, Johnson-Winegar, Anna G., Wintroub, Bruce U., Isseroff, Rivkah R., Epstein, Ervin H., Elias, Peter M.

“…Several problems have frustrated the isolation of lamellar bodies (LB) from mammalian epidermis. We obtained pellets enriched in intact LB by utilizing the…”
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Detection and partial characterization of a human mast cell carboxypeptidase by Goldstein, SM, Kaempfer, CE, Proud, D, Schwartz, LB, Irani, AM, Wintroub, BU

“…Using a high performance liquid chromatography assay that detects the cleavage of the C-terminal leucine from angiotensin I, we have identified a…”
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The granulocyte-angiotensin system. Angiotensin I-converting activity of cathepsin G by Klickstein, L B, Kaempfer, C E, Wintroub, B U

“…Cathepsin G, an Mr = 26,000-29,000 cationic human neutrophil lysosomal serine protease, releases angiotensin II from angiotensinogen and was, therefore,…”
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Cutaneous drug reactions: pathogenesis and clinical classification by Wintroub, B U, Stern, R

“…Cutaneous drug reactions may be classified with respect to pathogenesis and clinical morphology. They may be mediated by immunologic and nonimmunologic…”
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Erythropoietin Binding and Induced Differentiation of Rauscher Erythroleukemia Cell Line Red 5-1.5 by Weiss, T L, Barker, M E, Selleck, S E, Wintroub, B U

“…We isolated from the Rauscher erythroleukemia cell line (Red 5), a subclone (Red 5-1.5), which contains erythropoietin (epo) binding sites and demonstrates an…”
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Photosensitivity due to drugs by EPSTEIN, J. H, WINTROUB, B. U

“…Photosensitivity reactions induced by drugs may be phototoxic or photoallergic in nature. Acute phototoxic reactions are by far the more common, and are…”
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Angiotensin I Conversion by Human and Rat Chymotryptic Proteinases by Wintroub, Bruce U., Schechter, Norman B., Lazarus, Gerald S., Kaempfer, Carol E., Schwartz, Lawrence B.

“…Human skin chymotrypsin-like proteinase, human neutrophil cathepsin G, rat mast cell chymase, and rat salivary gland tonin are cell-derived serine proteinases…”
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A human platelet angiotensin I-processing system. Identification of components and inhibition of angiotensin-converting enzyme by product by Snyder, R A, Watt, K W, Wintroub, B U

“…Mechanisms controlling the local generation of angiotensin II by vascular tissue are incompletely understood. Human platelets were examined for their ability…”
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Combined total body X-ray irradiation and total skin electron beam radiotherapy with an improved technique for mycosis fungoides by Halberg, F E, Fu, K K, Weaver, K A, Zackheim, H S, Epstein, Jr, E H, Wintroub, B U

“…Twelve consecutive patients with advanced stage mycosis fungoides (MF) were treated with combined total body X ray irradiation (TBI) and total skin electron…”
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A human lung mast cell chymotrypsin-like enzyme: identification and partial characterization by WINTROUB, B. U, KAEMPFER, C. E, SCHECHTER, N. M, PROUD, D

“…We have used a high performance liquid chromatography assay, which detects chymotryptic cleavage of the phe8-his9 bond of angiotensin I to yield angiotensin…”
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Human Neutrophils Release Serine Proteases Capable of Activating Prorenin by Dzau, Victor J, Gonzalez, Debra, Kaempfer, Carol, Dubin, Daniel, Wintroub, Bruce U

“…Proteases from human neutrophils can generate angiotensin II directly from angiotensin I or angiotensinogen. We examined whether neutrophil protease also…”
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Bullous Pemphigoid, and Ultrastructural Study of the Inflammatory Response: Eosinophil, Basophil and Mast Cell Granule Changes in Multiple Biopsies from One Patient by Dvorak, Ann M., Mihm, Martin C., Osage, Justine E., Kwan, Theodore H., Austen, K. Frank, Wintroub, Bruce U.

“…We have studied by electron and light microscopy the inflammatory reaction in lesions at various stages of clinical development from a patient with bullous…”
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Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G by Wintroub, Bruce U, Klickstein, Lloyd B, Dzau, Victor J, Watt, Kenneth W. K

“…Cathepsin G, a human lysosomal neutral protease, converts angiotensin I to angiotensin II and cleaves angiotensin II from a plasma protein substrate…”
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Dermatology, the academic medical center, and the new millennium by Wintroub, B U

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Human Skin Mast Cell Carboxypeptidase: Functional Characterization, cDNA Cloning, and Genealogy by Natsuaki, Masaru, Stewart, Caro-Beth, Vanderslice, Peter, Schwartz, Lawrence B., Natsuaki, Megumi, Wintroub, Bruce U., Rutter, William J., Goldstein, Sanford M.

“…We functionally characterized human skin mast cell carboxypeptidase A (MC-CPA), and explored its evolutionary relationship to other carboxypeptidases to…”
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Identification of Chemoattractant Activity for Lymphocytes in Blister Fluid of Patients with Bullous Pemphigoid: Evidence for the Presence of a Lymphokine by Center, David M., Wintroub, Bruce U., Austen, K. Frank

“…Bullous pemphigoid is characterized by the dermal infiltration of lymphocytes, which precedes the striking influx of eosinophils as the lesion evolves into the…”
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