Search Results - "WINKLER, Matthias"
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The emerging role of FTY720 (Fingolimod) in cancer treatment
Published in Oncotarget (26-04-2016)“…FTY720 (Fingolimod) is a clinically approved immunomodulating therapy for multiple sclerosis that sequesters T-cells to lymph nodes through functional…”
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2
Renewable Polymers from Itaconic Acid by Polycondensation and Ring-Opening-Metathesis Polymerization
Published in Macromolecules (10-03-2015)“…Itaconic acid, a renewable feedstock obtained by fermentation of carbohydrates, is used as a key substrate to produce aliphatic unsaturated polyesters as well…”
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Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity
Published in Journal of medicinal chemistry (23-12-2010)“…Reversible lysine-specific acetylation has been described as an important posttranslational modification, regulating chromatin structure and transcriptional…”
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4
Making use of climate information for sustainable preservation of cultural heritage: applications to the KERES project
Published in Heritage science (26-01-2023)“…According to the final report of the European Union OMC expert group on strengthening cultural heritage resilience for anthropogenic climate change, the…”
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T-705-Derived Prodrugs Show High Antiviral Efficacies against a Broad Range of Influenza A Viruses with Synergistic Effects When Combined with Oseltamivir
Published in Pharmaceutics (01-06-2023)“…Emerging influenza A viruses (IAV) bear the potential to cause pandemics with unpredictable consequences for global human health. In particular, the WHO has…”
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Evaluating the Practicability of the new Urban Climate Model PALM-4U using a Living-Lab Approach
Published in E3S web of conferences (01-01-2020)“…Numerical urban climate models have the potential to be commonly used tools in urban development processes in practice. With integrated modules for building…”
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Investigating overheating by measurement and simulation in classrooms
Published in E3S web of conferences (01-01-2020)“…New two-story wood-construction classrooms where added to an existing heavy-weight construction school building in the year 2006. The glass façade of some…”
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Etoricoxib-induced toxic epidermal necrolysis: Successful treatment with infliximab
Published in Journal of dermatology (01-10-2010)Get full text
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User requirements and case studies to evaluate the practicability and usability of the urban climate model PALM‑4U
Published in Meteorologische Zeitschrift (Berlin, Germany : 1992) (01-01-2019)“…As cities are sensitive to climate change, they must be prepared for its consequences. While high-performance urban climate models are the basis for…”
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Use of a radiator for user-centric cooling – Measurement and Simulation
Published in E3S web of conferences (01-01-2020)“…With further increasing temperatures during warm summers, cooling of buildings is becoming more popular even in moderate middle or northern European climate…”
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11
The Robin Hood Narrative: A Discussion of Empirical and Ethical Legitimizations of Somali Pirates
Published in Ocean development and international law (01-04-2013)“…The pirates of Somalia pose a major challenge for the international community, both economically and morally. Somali pirates try to legitimize their actions by…”
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Basics for the operationalization of the new urban climate model PALM-4U
Published in Climate services (01-12-2020)Get full text
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13
Anwendung von höherfrequenten Hämmerverfahren bei Kranbahnträgern
Published in Der Stahlbau (01-12-2021)“…Die höherfrequenten Hämmerverfahren (HFH) sind Schweißnahtnachbehandlungsverfahren zur Steigerung der Ermüdungsfestigkeit von geschweißten Kerbdetails. Seit…”
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14
Examining Demand Effects on Direct and Indirect Affect Measures in Affect Induction Procedures
Published in Emotion (Washington, D.C.) (01-10-2024)“…Affect induction procedures are effectively implemented in psychological research. However, because participants are typically asked to self-report their…”
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Ertüchtigungsmaßnahmen für Kranbahnen zur Lebensdauerverlängerung
Published in Der Stahlbau (01-04-2024)“…In den meisten Industriebetrieben werden zur flurfreien Bewegung von Gütern Brückenkrane genutzt. Diese werden meist in Hallenlängsrichtung auf Kranbahnen…”
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Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and Its De-Fluoro Analogue T-1105 as Potent Influenza Virus Inhibitors
Published in Journal of medicinal chemistry (26-07-2018)“…We here disclose chemical synthesis of ribonucleoside 5'-monophosphate (RMP), -diphosphate (RDP), and -triphosphate (RTP) and cycloSal-, Di PPro-, and Tri…”
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Ertüchtigungsmaßnahmen für Kranbahnen zur Lebensdauerverlängerung
Published in Der Stahlbau (01-04-2024)“…In den meisten Industriebetrieben werden zur flurfreien Bewegung von Gütern Brückenkrane genutzt. Diese werden meist in Hallenlängsrichtung auf Kranbahnen…”
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18
Erhöhung der Ermüdungsfestigkeit von Hohlprofil‐K‐Knoten mittels formoptimierter Knotenbleche
Published in Der Stahlbau (01-06-2024)“…Die Ermüdungsfestigkeit von Tragwerken aus rechteckigen (RHS) und kreisförmigen Hohlprofilen (CHS) ist durch inhomogene Steifigkeitsverteilungen in den…”
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Effect of ET‐A blockade on portal pressure and hepatic arterial perfusion in patients with cirrhosis: A proof of concept study
Published in Liver international (01-03-2021)“…Background/aim Endothelin causes vasoconstriction via the endothelin‐A receptor (ET‐A) in the intrahepatic circulation in cirrhosis and its increase leads to…”
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Synthesis of T‐705‐Ribonucleoside and T‐705‐Ribonucleotide and Studies of Chemical Stability
Published in ChemMedChem (09-05-2017)“…T‐705 (favipiravir) is a fluorinated hydroxypyrazine carboxamide that exhibits antiviral activities against a variety of RNA viruses. Given the lack of potent…”
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