Search Results - "WINDER, Danny G"

A corticotropin releasing factor pathway for ethanol regulation of the ventral tegmental area in the bed nucleus of the stria terminalis by Silberman, Yuval, Matthews, Robert T, Winder, Danny G

“…A growing literature suggests that catecholamines and corticotropin-releasing factor (CRF) interact in a serial manner to activate the bed nucleus of the stria…”
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mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects by Joffe, Max E., Santiago, Chiaki I., Oliver, Kendra H., Maksymetz, James, Harris, Nicholas A., Engers, Julie L., Lindsley, Craig W., Winder, Danny G., Conn, P. Jeffrey

“…Non-selective antagonists of metabotropic glutamate receptor subtypes 2 (mGlu2) and 3 (mGlu3) exert rapid antidepressant-like effects by enhancing prefrontal…”
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Corticotropin releasing factor and catecholamines enhance glutamatergic neurotransmission in the lateral subdivision of the central amygdala by Silberman, Yuval, Winder, Danny G.

“…Glutamatergic neurotransmission in the central nucleus of the amygdala (CeA) plays an important role in many behaviors including anxiety, memory consolidation…”
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Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation by Shonesy, Brian C, Bluett, Rebecca J, Ramikie, Teniel S, Báldi, Rita, Hermanson, Daniel J, Kingsley, Philip J, Marnett, Lawrence J, Winder, Danny G, Colbran, Roger J, Patel, Sachin

“…Endocannabinoid (eCB) signaling has been heavily implicated in the modulation of anxiety and depressive behaviors and emotional learning. However, the role of…”
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Dynamic remodeling of a basolateral-to-central amygdala glutamatergic circuit across fear states by Hartley, Nolan D., Gaulden, Andrew D., Báldi, Rita, Winters, Nathan D., Salimando, Gregory J., Rosas-Vidal, Luis Eduardo, Jameson, Alexis, Winder, Danny G., Patel, Sachin

“…Acquisition and extinction of learned fear responses utilize conserved but flexible neural circuits. Here we show that acquisition of conditioned freezing…”
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Endocannabinoid signalling modulates susceptibility to traumatic stress exposure by Bluett, Rebecca J., Báldi, Rita, Haymer, Andre, Gaulden, Andrew D., Hartley, Nolan D., Parrish, Walker P., Baechle, Jordan, Marcus, David J., Mardam-Bey, Ramzi, Shonesy, Brian C., Uddin, Md. Jashim, Marnett, Lawrence J., Mackie, Ken, Colbran, Roger J., Winder, Danny G., Patel, Sachin

“…Stress is a ubiquitous risk factor for the exacerbation and development of affective disorders including major depression and posttraumatic stress disorder…”
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Delineation of an insula-BNST circuit engaged by struggling behavior that regulates avoidance in mice by Luchsinger, Joseph R., Fetterly, Tracy L., Williford, Kellie M., Salimando, Gregory J., Doyle, Marie A., Maldonado, Jose, Simerly, Richard B., Winder, Danny G., Centanni, Samuel W.

“…Active responses to stressors involve motor planning, execution, and feedback. Here we identify an insular cortex to BNST (insula →BNST ) circuit recruited…”
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BNST-insula structural connectivity in humans by Flook, Elizabeth A., Feola, Brandee, Avery, Suzanne N., Winder, Danny G., Woodward, Neil D., Heckers, Stephan, Blackford, Jennifer Urbano

“…The bed nucleus of the stria terminalis (BNST) is emerging as a critical region in multiple psychiatric disorders including anxiety, PTSD, and alcohol and…”
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Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal by Porter-Stransky, Kirsten A., Centanni, Samuel W., Karne, Saumya L., Odil, Lindsay M., Fekir, Sinda, Wong, Jennifer C., Jerome, Canaan, Mitchell, Heather A., Escayg, Andrew, Pedersen, Nigel P., Winder, Danny G., Mitrano, Darlene A., Weinshenker, David

“…Dysregulation of arousal is symptomatic of numerous psychiatric disorders. Previous research has shown that the activity of dopamine (DA) neurons in the…”
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BNST PKCδ neurons are activated by specific aversive conditions to promote anxiety-like behavior by Williford, Kellie M, Taylor, Anne, Melchior, James R, Yoon, Hye Jean, Sale, Eryn, Negasi, Milen D, Adank, Danielle N, Brown, Jordan A, Bedenbaugh, Michelle N, Luchsinger, Joseph R, Centanni, Samuel W, Patel, Sachin, Calipari, Erin S, Simerly, Richard B, Winder, Danny G

“…The bed nucleus of the stria terminalis (BNST) is a critical mediator of stress responses and anxiety-like behaviors. Neurons expressing protein kinase C delta…”
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Repeated Homotypic Stress Elevates 2-Arachidonoylglycerol Levels and Enhances Short-Term Endocannabinoid Signaling at Inhibitory Synapses in Basolateral Amygdala by Patel, Sachin, Kingsley, Philip J, Mackie, Ken, Marnett, Lawrence J, Winder, Danny G

“…Psychosocial stress is a risk factor for development and exacerbation of neuropsychiatric illness. Repeated stress causes biochemical adaptations in…”
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Neuropeptide Y and corticotropin-releasing factor bi-directionally modulate inhibitory synaptic transmission in the bed nucleus of the stria terminalis by Kash, Thomas L., Winder, Danny G.

“…Neuropeptide Y (NPY) and corticotropin-releasing factor (CRF) have opposing effects on stress and anxiety. Both can modify synaptic activity through their…”
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Dorsolateral Striatum Engagement Interferes with Early Discrimination Learning by Bergstrom, Hadley C., Lipkin, Anna M., Lieberman, Abby G., Pinard, Courtney R., Gunduz-Cinar, Ozge, Brockway, Emma T., Taylor, William W., Nonaka, Mio, Bukalo, Olena, Wills, Tiffany A., Rubio, F. Javier, Li, Xuan, Pickens, Charles L., Winder, Danny G., Holmes, Andrew

“…In current models, learning the relationship between environmental stimuli and the outcomes of actions involves both stimulus-driven and goal-directed systems,…”
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Roles of serine/threonine phosphatases in hippocampel synaptic plasticity by Winder, Danny G, Sweatt, J. David

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Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior by Shonesy, Brian C., Parrish, Walker P., Haddad, Hala K., Stephenson, Jason R., Báldi, Rita, Bluett, Rebecca J., Marks, Christian R., Centanni, Samuel W., Folkes, Oakleigh M., Spiess, Keeley, Augustin, Shana M., Mackie, Ken, Lovinger, David M., Winder, Danny G., Patel, Sachin, Colbran, Roger J.

“…Endocannabinoid signaling plays an important role in regulating synaptic transmission in the striatum, a brain region implicated as a central node of…”
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GluN2B subunit deletion reveals key role in acute and chronic ethanol sensitivity of glutamate synapses in bed nucleus of the stria terminalis by Wills, Tiffany A, Klug, Jason R, Silberman, Yuval, Baucum, Anthony J, Weitlauf, Carl, Colbran, Roger J, Delpire, Eric, Winder, Danny G

“…The bed nucleus of the stria terminalis (BNST) is a critical region for alcohol/drug-induced negative affect and stress-induced reinstatement. NMDA receptor…”
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Dopamine Enhances Fast Excitatory Synaptic Transmission in the Extended Amygdala by a CRF-R1-Dependent Process by Kash, Thomas L, Nobis, William P, Matthews, Robert T, Winder, Danny G

“…A common feature of drugs of abuse is their ability to increase extracellular dopamine levels in key brain circuits. The actions of dopamine within these…”
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Changes in the Adult GluN2B Associated Proteome following Adolescent Intermittent Ethanol Exposure by Swartzwelder, H Scott, Risher, Mary-Louise, Miller, Kelsey M, Colbran, Roger J, Winder, Danny G, Wills, Tiffany A

“…Adolescent alcohol use is the strongest predictor for alcohol use disorders. In rodents, adolescents have distinct responses to acute ethanol, and prolonged…”
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Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress by McElligott, Zoé A, Klug, Jason R, Nobis, William P, Patel, Sachin, Grueter, Brad A, Kash, Thomas L, Winder, Danny G

“…Long-term depression (LTD) is an important synaptic mechanism for limiting excitatory influence over circuits subserving cognitive and emotional behavior. A…”
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Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability by Klug, Jason R, Mathur, Brian N, Kash, Thomas L, Wang, Hui-Dong, Matthews, Robert T, Robison, A J, Anderson, Mark E, Deutch, Ariel Y, Lovinger, David M, Colbran, Roger J, Winder, Danny G

“…Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is abundant in striatal medium spiny neurons (MSNs). CaMKII is dynamically regulated by changes in…”
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