Search Results - "WILSON, Micheal C"
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Structure and Biosynthesis of the Marine Streptomycete Ansamycin Ansalactam A and Its Distinctive Branched Chain Polyketide Extender Unit
Published in Journal of the American Chemical Society (16-02-2011)“…Reported is the structure and biosynthesis of ansalactam A, an ansamycin class polyketide produced by an unusual modification of the polyketide pathway. This…”
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Shared Biosynthesis of the Saliniketals and Rifamycins in Salinispora arenicola is Controlled by the sare1259-Encoded Cytochrome P450
Published in Journal of the American Chemical Society (15-09-2010)“…Saliniketals A and B are unusual polyketides from the marine actinomycete Salinispora arenicola that inhibit ornithine decarboxylase induction. The structural…”
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Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity
Published in Natural product reports (01-01-2012)“…This review covers the emerging biosynthetic role of crotonyl-CoA carboxylase/reductase (CCR) homologs in extending the structural and functional diversity of…”
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Designed Biosynthesis of 36-Methyl-FK506 by Polyketide Precursor Pathway Engineering
Published in ACS synthetic biology (19-07-2013)“…The polyketide synthase (PKS) biosynthetic code has recently expanded to include a newly recognized group of extender unit substrates derived from…”
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An environmental bacterial taxon with a large and distinct metabolic repertoire
Published in Nature (London) (06-02-2014)“…Cultivated bacteria such as actinomycetes are a highly useful source of biomedically important natural products. However, such ‘talented’ producers represent…”
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Metagenomic Approaches for Exploiting Uncultivated Bacteria as a Resource for Novel Biosynthetic Enzymology
Published in Chemistry & biology (23-05-2013)“…Most biologically active microbial natural products are known from strains that can be isolated and cultivated in the laboratory. However, the genomics era has…”
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Single-bacterial genomics validates rich and varied specialized metabolism of uncultivated Entotheonella sponge symbionts
Published in Proceedings of the National Academy of Sciences - PNAS (20-02-2018)“…Marine sponges are prolific sources of unique bioactive natural products. The sponge Theonella swinhoei is represented by several distinct variants with…”
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The Discovery of Salinosporamide K from the Marine Bacterium "Salinispora pacifica" by Genome Mining Gives Insight into Pathway Evolution
Published in Chembiochem : a European journal of chemical biology (03-01-2011)“…Evolving biosynthesis: Genome mining of the marine bacterium “Salinispora pacifica” has led to the discovery of the new proteasome inhibitor, salinosporamide…”
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Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses
Published in Applied and Environmental Microbiology (01-06-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Corrigendum: an environmental bacterial taxon with a large and distinct metabolic repertoire
Published in Nature (London) (13-03-2014)Get full text
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Correction: Corrigendum: An environmental bacterial taxon with a large and distinct metabolic repertoire
Published in Nature (London) (13-03-2014)“…Nature 506, 58–62 (2014); doi:10.1038/nature12959 One of the accession numbers for this Article was listed as AZHXW01000000 instead of AZHX01000000. It has…”
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Erratum: Corrigendum: An environmental bacterial taxon with a large and distinct metabolic repertoire
Published in Nature (London) (12-03-2014)Get full text
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