Search Results - "WILSON, Darrell M"

Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes by Yu, Wong, Jiang, Ning, Ebert, Peter J.R., Kidd, Brian A., Müller, Sabina, Lund, Peder J., Juang, Jeremy, Adachi, Keishi, Tse, Tiffany, Birnbaum, Michael E., Newell, Evan W., Wilson, Darrell M., Grotenbreg, Gijsbert M., Valitutti, Salvatore, Quake, Stephen R., Davis, Mark M.

“…It has long been thought that clonal deletion efficiently removes almost all self-specific T cells from the peripheral repertoire. We found that self-peptide…”
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Predictive Low-Glucose Insulin Suspension Reduces Duration of Nocturnal Hypoglycemia in Children Without Increasing Ketosis by Buckingham, Bruce A, Raghinaru, Dan, Cameron, Fraser, Bequette, B Wayne, Chase, H Peter, Maahs, David M, Slover, Robert, Wadwa, R Paul, Wilson, Darrell M, Ly, Trang, Aye, Tandy, Hramiak, Irene, Clarson, Cheril, Stein, Robert, Gallego, Patricia H, Lum, John, Sibayan, Judy, Kollman, Craig, Beck, Roy W

“…Nocturnal hypoglycemia can cause seizures and is a major impediment to tight glycemic control, especially in young children with type 1 diabetes. We conducted…”
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Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial by Orban, Tihamer, MD, Bundy, Brian, PhD, Becker, Dorothy J, Prof, DiMeglio, Linda A, MD, Gitelman, Stephen E, Prof, Goland, Robin, Prof, Gottlieb, Peter A, Prof, Greenbaum, Carla J, MD, Marks, Jennifer B, Prof, Monzavi, Roshanak, MD, Moran, Antoinette, Prof, Raskin, Philip, Prof, Rodriguez, Henry, Prof, Russell, William E, Prof, Schatz, Desmond, Prof, Wherrett, Diane, MD, Wilson, Darrell M, Prof, Krischer, Jeffrey P, Prof, Skyler, Jay S, Dr, Prof

“…Summary Background The immunopathogenesis of type 1 diabetes mellitus is associated with T-cell autoimmunity. To be fully active, immune T cells need a…”
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A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes by MAAHS, David M, CALHOUN, Peter, SLOVER, Robert, PAUL WADWA, R, WILSON, Darrell M, KOLLMAN, Craig, BECK, Roy W, BUCKINGHAM, Bruce A, PETER CHASE, H, HRAMIAK, Irene, LUM, John, CAMERON, Fraser, WAYNE BEQUETTE, B, AYE, Tandy, PAUL, Terri

“…Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an…”
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Large Doses of Vitamin D Fail to Increase 25-Hydroxyvitamin D Levels or to Alter Cardiovascular Risk Factors in Obese Adolescents: A Pilot Study by Shah, Sejal, M.D, Wilson, Darrell M., M.D, Bachrach, Laura K., M.D

“…Abstract Purpose Vitamin D deficiency and cardiometabolic risk factors are common in obese adolescents. Observational studies demonstrate an inverse…”
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Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial by Wherrett, Diane K, MD, Bundy, Brian, PhD, Becker, Dorothy J, Prof, DiMeglio, Linda A, MD, Gitelman, Stephen E, Prof, Goland, Robin, Prof, Gottlieb, Peter A, Prof, Greenbaum, Carla J, MD, Herold, Kevan C, Prof, Marks, Jennifer B, Prof, Monzavi, Roshanak, MD, Moran, Antoinette, Prof, Orban, Tihamer, MD, Palmer, Jerry P, MD, Raskin, Philip, Prof, Rodriguez, Henry, Prof, Schatz, Desmond, Prof, Wilson, Darrell M, Prof, Krischer, Jeffrey P, Prof, Skyler, Jay S, Dr, Prof

“…Summary Background Glutamic acid decarboxylase (GAD) is a major target of the autoimmune response that occurs in type 1 diabetes mellitus. In animal models of…”
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Sensitive detection of multiple islet autoantibodies in type 1 diabetes using small sample volumes by agglutination-PCR by Cortez, Felipe de Jesus, Gebhart, David, Robinson, Peter V, Seftel, David, Pourmandi, Narges, Owyoung, Jordan, Bertozzi, Carolyn R, Wilson, Darrell M, Maahs, David M, Buckingham, Bruce A, Mills, John R, Roforth, Matthew M, Pittock, Sean J, McKeon, Andrew, Page, Kara, Wolf, Wendy A, Sanda, Srinath, Speake, Cate, Greenbaum, Carla J, Tsai, Cheng-Ting

“…Islet autoantibodies are predominantly measured by radioassay to facilitate risk assessment and diagnosis of type 1 diabetes. However, the reliance on…”
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Duration of Nocturnal Hypoglycemia Before Seizures by Buckingham, Bruce, Wilson, Darrell M, Lecher, Todd, Hanas, Ragnar, Kaiserman, Kevin, Cameron, Fergus

“…OBJECTIVE:--Despite a high incidence of nocturnal hypoglycemia documented by the use of continuous glucose monitoring (CGM), there are no reports in the…”
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Feasibility of Detecting Neuropsychologic and Neuroanatomic Effects of Type 1 Diabetes in Young Children by Aye, Tandy, Reiss, Allan L, Kesler, Shelli, Hoang, Sherry, Drobny, Jessica, Park, Yaena, Schleifer, Kristin, Baumgartner, Heidi, Wilson, Darrell M, Buckingham, Bruce A

“…OBJECTIVE: To determine if frequent exposures to hypoglycemia and hyperglycemia during early childhood lead to neurocognitive deficits and changes in brain…”
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Relation of body fat indexes to vitamin D status and deficiency among obese adolescents by Lenders, Carine M, Feldman, Henry A, Von Scheven, Emily, Merewood, Anne, Sweeney, Carol, Wilson, Darrell M, Lee, Phillip DK, Abrams, Stephanie H, Gitelman, Stephen E, Wertz, Marcia S, Klish, William J, Taylor, George A, Chen, Tai C, Holick, Michael F

“…BACKGROUND: Data on the relation between vitamin D status and body fat indexes in adolescence are lacking. OBJECTIVE: The objective was to identify factors…”
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Optimal sampling intervals to assess long-term glycemic control using continuous glucose monitoring by Xing, Dongyuan, Kollman, Craig, Beck, Roy W, Tamborlane, William V, Laffel, Lori, Buckingham, Bruce A, Wilson, Darrell M, Weinzimer, Stuart, Fiallo-Scharer, Rosanna, Ruedy, Katrina J

“…The optimal duration and frequency of short-term continuous glucose monitoring (CGM) to reflect long-term glycemia have not been determined. The Juvenile…”
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One Year Clinical Experience of the First Commercial Hybrid Closed-Loop System by Lal, Rayhan A, Basina, Marina, Maahs, David M, Hood, Korey, Buckingham, Bruce, Wilson, Darrell M

“…In September 2016, the U.S. Food and Drug Administration approved the Medtronic 670G "hybrid" closed-loop system. In Auto Mode, this system automatically…”
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Two-Center Randomized Controlled Feasibility Trial of Insulin Pump Therapy in Young Children With Diabetes by Wilson, Darrell M, Buckingham, Bruce A, Kunselman, Elizabeth L, Sullivan, Mary M, Paguntalan, Helen U, Gitelman, Stephen E

“…OBJECTIVE:--Our goals were to determine if continuous subcutaneous insulin infusion (CSII), compared with those continuing multiple daily injections (MDIs),…”
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Predictive hyperglycemia and hypoglycemia minimization: In‐home double‐blind randomized controlled evaluation in children and young adolescents by Forlenza, Gregory P, Raghinaru, Dan, Cameron, Faye, Wayne Bequette, B, Peter Chase, H, Paul Wadwa, R, Maahs, David M, Jost, Emily, Ly, Trang T, Wilson, Darrell M, Norlander, Lisa, Ekhlaspour, Laya, Min, Hyojin, Clinton, Paula, Njeru, Nelly, Lum, John W, Kollman, Craig, Beck, Roy W, Buckingham, Bruce A

“…Objective The primary objective of this trial was to evaluate the feasibility, safety, and efficacy of a predictive hyperglycemia and hypoglycemia minimization…”
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Automation of a multiplex agglutination-PCR (ADAP) type 1 diabetes (T1D) assay for the rapid analysis of islet autoantibodies by Cortez, Felipe de Jesus, Gebhart, David, Tandel, Devangkumar, Robinson, Peter V., Seftel, David, Wilson, Darrell M., Maahs, David M., Buckingham, Bruce A., Miller, Kevin W.P., Tsai, Cheng-ting

“…Screening for islet autoantibody markers to identify individuals who are at high risk for developing type 1 diabetes (T1D), often years in advance of clinical…”
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The Accuracy of the FreeStyle Navigator Continuous Glucose Monitoring System in Children With Type 1 Diabetes by WILSON, Darrell M, BECK, Roy W, TAMBORLANE, William V, DONTCHEV, Mariya J, KOLLMAN, Craig, CHASE, Peter, FOX, Larry A, RUEDY, Katrina J, TSALIKIAN, Eva, WEINZIMER, Stuart A

“…The Accuracy of the FreeStyle Navigator Continuous Glucose Monitoring System in Children With Type 1 Diabetes Darrell M. Wilson , MD , Roy W. Beck , MD, PHD ,…”
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Sequential Comparisons of One-Month and Three-Month Depot Leuprolide Regimens in Central Precocious Puberty by Badaru, Angela, Wilson, Darrell M., Bachrach, Laura K., Fechner, Patricia, Gandrud, Laura M., Durham, Eileen, Wintergerst, Kupper, Chi, Carolyn, Klein, Karen O., Neely, E. Kirk

“…Background: Dosing of monthly depot leuprolide (DL) in central precocious puberty (CPP) varies considerably. U.S. practitioners use 7.5–15 mg, in contrast with…”
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The interrelationships of glycemic control measures: HbA1c, glycated albumin, fructosamine, 1,5-anhydroglucitrol, and continuous glucose monitoring by Beck, Roy, Steffes, Michael, Xing, Dongyuan, Ruedy, Katrina, Mauras, Nelly, Wilson, Darrell M, Kollman, Craig

“…Beck R, Steffes M, Xing D, Ruedy K, Mauras N, Wilson DM, Kollman C, the Diabetes Research in Children Network (DirecNet) Study Group. The interrelationships of…”
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1000-P: The Effects of Neighborhood Characteristics on Youth with Type 2 Diabetes Mellitus by NI, JENNIFER, ADDALA, ANANTA, WILSON, DARRELL M., PRAHALAD, PRIYA

“…Type 2 diabetes mellitus (T2D) in youth has become an increasingly pressing issue over the last two decades. Emerging data from adult studies show associations…”
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Clonal Deletion Prunes but Does Not Eliminate Self-Specific alpha beta CD8+ T Lymphocytes by Yu, Wong, Jiang, Ning, Ebert, Peter JR, Kidd, Brian A, Mueller, Sabina, Lund, Peder J, Juang, Jeremy, Adachi, Keishi, Tse, Tiffany, Birnbaum, Michael E, Newell, Evan W, Wilson, Darrell M, Grotenbreg, Gijsbert M, Valitutti, Salvatore, Quake, Stephen R, Davis, Mark M

“…It has long been thought that clonal deletion efficiently removes almost all self-specific T cells from the peripheral repertoire. We found that self-peptide…”
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