Search Results - "WILLIAMS, R G"

Neurodevelopmental and Neurophysiological Actions of Thyroid Hormone by Williams, G. R.

“…For over 100 years, thyroid hormones have been known to be essential for neonatal neurodevelopment but whether they are required by the foetal brain remains a…”
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ATF3 transcription factor and its emerging roles in immunity and cancer by Thompson, Matthew R., Xu, Dakang, Williams, Bryan R. G.

“…Activating transcription factor 3 (ATF3) is a member of the ATF/cyclic AMP response element-binding (ATF/CREB) family of transcription factors. It is an…”
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Muscle composition and outcomes in patients with breast cancer: meta-analysis and systematic review by Aleixo, G. F. P., Williams, G. R., Nyrop, K. A., Muss, H. B., Shachar, S. S.

“…Purpose Breast cancer is the most common cancer and leading cause of cancer death in women. Body composition parameters, especially those related to muscle,…”
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Interferon-inducible antiviral effectors by Williams, Bryan R. G, Sadler, Anthony J

“…Key Points Interferons (IFNs) are key components of the innate immune response and the first line of defence against virus infection. Among the hundreds of…”
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Analysis of microRNA turnover in mammalian cells following Dicer1 ablation by Gantier, Michael P., McCoy, Claire E., Rusinova, Irina, Saulep, Damien, Wang, Die, Xu, Dakang, Irving, Aaron T., Behlke, Mark A., Hertzog, Paul J., Mackay, Fabienne, Williams, Bryan R. G.

“…Although microRNAs (miRNAs) are key regulators of gene expression, little is known of their overall persistence in the cell following processing…”
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Resource Availability and Entrainment Are Driven by Offsets Between Nutriclines and Winter Mixed‐Layer Depth by Rigby, S. J., Williams, R. G., Achterberg, E. P., Tagliabue, A.

“…While phytoplankton play a key role in ocean biogeochemical cycles, the availability and supply pathways of resources that support their growth remain poorly…”
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Negative Regulation of TLR-Signaling Pathways by Activating Transcription Factor-3 by Whitmore, Mark M, Iparraguirre, Amaya, Kubelka, Lindsey, Weninger, Wolfgang, Hai, Tsonwin, Williams, Bryan R. G

“…Activating transcription factor-3 (ATF3) is rapidly induced by LPS in mouse macrophages and regulates TLR4 responses. We show that ATF3 is rapidly induced by…”
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Weight gain during adjuvant endocrine treatment for early-stage breast cancer: What is the evidence? by Nyrop, K. A., Williams, G. R., Muss, H. B., Shachar, S. S.

“…Most breast cancer (BC) tumors are early stage and hormone receptor positive, where treatment generally includes adjuvant endocrine treatment (ET). Oncology…”
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Tendon to bone healing: differences in biomechanical, structural, and compositional properties due to a range of activity levels by Thomopoulos, S, Williams, G R, Soslowsky, L J

“…Little knowledge exists about the healing process of the tendon to bone insertion, and hence little can be done to improve tissue healing. The goal of this…”
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Variations in the difference between mean sea level measured either side of Cape Hatteras and their relation to the North Atlantic Oscillation by Woodworth, P. L., Morales Maqueda, M. Á., Gehrels, W. R., Roussenov, V. M., Williams, R. G., Hughes, C. W.

“…We consider the extent to which the difference in mean sea level (MSL) measured on the North American Atlantic coast either side of Cape Hatteras varies as a…”
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Extrathyroidal expression of TSH receptor by Williams, G.R

“…Résumé Le récepteur de TSH s’exprime à la surface des cellules folliculaires de la thyroïde et possèdent un rôle crucial dans la régulation de la fonction et…”
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TLR7 Is Involved in Sequence-Specific Sensing of Single-Stranded RNAs in Human Macrophages by Gantier, Michael P, Tong, Stephen, Behlke, Mark A, Xu, Dakang, Phipps, Simon, Foster, Paul S, Williams, Bryan R. G

“…Human TLR7 and 8 (hTLR7/8) have been implicated in the sequence-dependent detection of RNA oligonucleotides in immune cells. Although hTLR7 sequence-specific…”
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The kinase activity of PKR represses inflammasome activity by Yim, Howard CH, Wang, Die, Yu, Liang, White, Christine L, Faber, Pieter W, Williams, Bryan RG, Sadler, Anthony J

“…The protein kinase R （PKR） functions in the antiviral response by controlling protein translation and inflamma- tory cell signaling pathways. We generated a…”
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Association of body composition with function in women with early breast cancer by Aleixo, G. F. P., Deal, A. M., Nyrop, K. A., Muss, H. B., Damone, E. M., Williams, G. R., Yu, H., Shachar, S. S.

“…Background Advances in breast cancer research are making treatment options increasingly effective and reducing mortality. Body composition is an example of a…”
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Early and eighteen month clinical outcomes of first UK case of percutaneous deep vein arterialisation (pDVA) to treat “no option” chronic limb-threatening ischemia using the LimFlow system by Lechareas, Symeon, Sritharan, Kaji, Williams, R. G. Mc

“…Background Chronic limb-threatening ischaemia (CLTI) in cases where there are no further standard treatment options for limb salvage represents the most…”
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A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells by Williams, Bryan RG, Marques, Joao Trindade, Devosse, Thalie, Wang, Die, Zamanian-Daryoush, Maryam, Serbinowski, Paul, Hartmann, Rune, Fujita, Takashi, Behlke, Mark A

“…Nonspecific effects triggered by small interfering RNAs (siRNAs) complicate the use of RNA interference (RNAi) to specifically downregulate gene expression. To…”
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Low bone mineral density is related to high physiological levels of free thyroxine in peri-menopausal women by van Rijn, L E, Pop, V J, Williams, G R

“…ObjectiveTo determine whether thyroid hormone (free thyroxine (fT4)) rather than TSH is directly related to bone mineral density (BMD).DesignCross-sectional…”
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PKR and RNase L Contribute to Protection against Lethal West Nile Virus Infection by Controlling Early Viral Spread in the Periphery and Replication in Neurons by SAMUEL, Melanie A, WHITBY, Kevin, KELLER, Brian C, MARRI, Anantha, BARCHET, Winfried, WILLIAMS, Bryan R. G, SILVERMAN, Robert H, GALE, Michael, DIAMOND, Michael S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Understanding immune phenotypes in human gastric disease tissues by multiplexed immunohistochemistry by Ying, Le, Yan, Feng, Meng, Qiaohong, Yuan, Xiangliang, Yu, Liang, Williams, Bryan R G, Chan, David W, Shi, Liyun, Tu, Yugang, Ni, Peihua, Wang, Xuefeng, Xu, Dakang, Hu, Yiqun

“…Understanding immune phenotypes and human gastric disease in situ requires an approach that leverages multiplexed immunohistochemistry (mIHC) with…”
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BTB-ZF transcriptional regulator PLZF modifies chromatin to restrain inflammatory signaling programs by Sadler, Anthony J., Rossello, Fernando J., Yu, Liang, Deane, James A., Yuan, Xiangliang, Wang, Die, Irving, Aaron T., Kaparakis-Liaskos, Maria, Gantier, Michael P., Ying, Hangjie, Yim, Howard C. H., Hartland, Elizabeth L., Notini, Amanda J., de Boer, Suzan, White, Stefan J., Mansell, Ashley, Liu, Jun-Ping, Watkins, D. Neil, Gerondakis, Steve, Williams, Bryan R. G., Xu, Dakang

“…Inflammation is critical for host defense, but without appropriate control, it can cause chronic disease or even provoke fatal responses. Here we identify a…”
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