Search Results - "WILLERSON, J. T"

Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-γ activators by PASCERI, V, WU, H. D, WILLERSON, J. T, YEH, E. T. H

“…Peroxisome proliferator-activated receptor-gamma (PPARgamma) is expressed in atherosclerotic plaques and in endothelial cells. The possible effects of…”
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Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations : Main results of the GUARDIAN trial by THEROUX, P, CHAITMAN, B. R, DANCHIN, N, ERHARDT, L, MEINERTZ, T, SCHROEDER, J. S, TOGNONI, G, WHITE, H. D, WILLERSON, J. T, JESSEL, A

“…Background —The transmembrane sodium/hydrogen exchanger maintains myocardial cell pH integrity during myocardial ischemia but paradoxically may precipitate…”
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Role of inflammation in coronary plaque disruption by Buja, L M, Willerson, J T

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Specific platelet mediators and unstable coronary artery lesions: experimental evidence and potential clinical implications by WILLERSON, J. T, GOLINO, P, EIDT, J, CAMPBELL, W. B, BUJA, L. M

“…We have speculated previously that the abrupt conversion from chronic stable to unstable angina and the continuum to acute myocardial infarction may result…”
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Thermal detection of cellular infiltrates in living atherosclerotic plaques: possible implications for plaque rupture and thrombosis by Casscells, W, Hathorn, B, David, M, Krabach, T, Vaughn, W K, McAllister, H A, Bearman, G, Willerson, J T

“…Atherosclerotic lesions are heterogeneous and prognosis cannot easily be predicted, even with intracoronary ultrasound and angioscopy. Serial angiographic and…”
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One-year results of the Thrombolysis in Myocardial Infarction (TIMI) IIIB clinical trial : a randomized comparison of tissue-type plasminogen activator versus placebo and early invasive versus early conservative strategies in unstable angina and non-Q wave myocardial infarction by ANDERSON, H. V, CANNON, C. P, STONE, P. H, WILLIAMS, D. O, MCCABE, C. H, KNATTERUD, G. L, THOMPSON, B, WILLERSON, J. T, BRAUNWALD, E

“…We report mortality, infarction, revascularization and repeat hospital admission events for 1 year after enrollment and randomization in the Thrombolysis in…”
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Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration by MADONNA, Rosalinda, DE CATERINA, Raffaele, WILLERSON, James T, GENG, Yong-Jian

“…Telomeres comprise long tracts of double-stranded TTAGGG repeats that extend for 9-15 kb in humans. Telomere length is maintained by telomerase, a specialized…”
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Thromboresistance of balloon-injured porcine carotid arteries after local gene transfer of human tissue factor pathway inhibitor by ZOLDHELYI, P, MCNATT, J, SHELAT, H. S, YAMAMOTO, Y, CHEN, Z.-Q, WILLERSON, J. T

“…Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of factor Xa and the coagulant initiator complex tissue factor/factor VIIa. To study the…”
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Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries by SHENG-KUN YAO, OBER, J. C, KRISHNASWAMI, A, FERGUSON, J. J, ANDERSON, V, GOLINO, P, MAXIMILIAN BUJA, L, WILLERSON, J. T

“…This study was designed to test the hypothesis that endogenously produced nitric oxide protects against platelet aggregation and cyclic flow variations in…”
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Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-α, in patients with moderate-to-severe Heart failure: Results of the anti-TNF therapy against congestive Heart failure (ATTACH) trial by CHUNG, Eugene S, PACKER, Milton, KIM HUNG LO, FASANMADE, Adedigbo A, WILLERSON, James T

“…Preclinical and preliminary clinical data have suggested that tumor necrosis factor-alpha (TNFalpha) may play a role in the evolution and progression of heart…”
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Thrombin is an important mediator of platelet aggregation in stenosed canine coronary arteries with endothelial injury by EIDT, J. F, ALLISON, P, NOBLE, S, ASHTON, J, GOLINO, P, MCNATT, J, BUJA, L. M, WILLERSON, J. T

“…Cyclic variations in coronary blood flow (CFVs) in dogs with experimental coronary artery stenosis and endothelial injury appear to result primarily from the…”
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Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells by CALABRO, Paolo, WILLERSON, James T, YEH, Edward T. H

“…Serum C-reactive protein (CRP) levels are good predictors of the development of cardiovascular events in apparently healthy men and women. CRP has been…”
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Direct proinflammatory effect of C-reactive protein on human endothelial cells by PASCERI, Vincenzo, WILLERSON, James T, YEH, Edward T. H

“…The acute-phase reactant C-reactive protein (CRP) is an important risk factor for coronary heart disease. However, the possible effects of CRP on vascular…”
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Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo by YEH, Edward T. H, SUI ZHANG, WU, Henry D, KÖRBLING, Martin, WILLERSON, James T, ESTROV, Zeev

“…Adult human peripheral blood cells have been shown to differentiate into mature cells of nonhematopoietic tissues, such as hepatocytes and epithelial cells of…”
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Intracellular Calcium Transients and Arrhythmia in Isolated Heart Cells by Thandroyen, F T, Morris, A C, Hagler, H K, Ziman, B, Pai, L, Willerson, J T, Buja, L M

“…Intracellular calcium ([Ca]i) elevation may mediate cardiac arrhythmias. However, direct measurement of the rapid alterations of [Ca], on a beat-to-beat basis…”
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Use of A direct antithrombin, hirulog, in place of heparin during coronary angioplasty by TOPOL, E. J, BONAN, R, GANZ, P, COHEN, M. D, RAYMOND, R, FOX, I, MARAGANORE, J, ADELMAN, B, JEWITT, D, SIGWART, U, KAKKAR, V. V, ROTHMAN, M, DE BONO, D, FERGUSON, J, WILLERSON, J. T, STRONY, J

“…Since the inception of coronary angioplasty, heparin with or without aspirin has been routinely given intraprocedurally to avoid coronary thrombotic…”
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Design of the Blockade of the Glycoprotein IIb/IIIa Receptor to Avoid Vascular Occlusion (BRAVO) trial by Topol, Eric J., Easton, J.Donald, Amarenco, Pierre, Califf, Robert, Harrington, Robert, Graffagnino, Carmen, Davis, Stephen, Diener, H.C., Ferguson, James, Fitzgerald, Desmond, Shuaib, Ashfaq, Koudstaal, Peter J., Theroux, Pierre, Van de Werf, Frans, Willerson, James T., Chan, Robert, Samuels, Robert, Ilson, Bernard, Granett, Jeffrey

“…Background Platelets play a key role in the pathogenesis of atherosclerosis, thrombosis, and acute coronary and cerebrovascular syndromes. Inhibition of…”
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Vulnerable atherosclerotic plaque: A multifocal disease by CASSCELLS, Ward, NAGHAVI, Morteza, WILLERSON, James T

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Coming of age of C-reactive protein: Using inflammation markers in cardiology by YEH, Edward T. H, WILLERSON, James T

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Synthesis of Lipoxygenase and Epoxygenase Products of Arachidonic Acid by Normal and Stenosed Canine Coronary Arteries by Rosolowsky, Mark, Falck, J R, Willerson, James T, Campbell, William B

“…Coronary vascular injury promotes blood cell-vessel wall interactions that influence arachidonic acid metabolism and coronary blood flow patterns. Since…”
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