Search Results - "WILLEMZE, Roel"

Mesenchymal Stem Cells Inhibit Generation and Function of Both CD34+-Derived and Monocyte-Derived Dendritic Cells by Nauta, Alma J, Kruisselbrink, Alwine B, Lurvink, Ellie, Willemze, Roel, Fibbe, Willem E

“…Mesenchymal stem cells (MSCs) are not only able to evade the immune system, but they have also been demonstrated to exert profound immunosuppressive properties…”
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Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting by Nauta, Alma J., Westerhuis, Geert, Kruisselbrink, Alwine B., Lurvink, Ellie G.A., Willemze, Roel, Fibbe, Willem E.

“…Mesenchymal stem cells (MSCs) are multipotent progenitor cells that have emerged as a promising tool for clinical application. Further clinical interest has…”
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Allogeneic Hematopoietic Stem-Cell Transplantation for Patients 50 Years or Older With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia by ZIYI LIM, BRAND, Ronald, RUUTU, Tapani, BOOGAERTS, Marc, FALDA, Michele, JOUET, Jean-Pierre, NIEDERWIESER, Dietger, KROGER, Nicolaus, MUFTI, Ghulam J, DE WITTE, Theo M, MARTINO, Rodrigo, VAN BIEZEN, Anja, FINKE, Jürgen, BACIGALUPO, Andrea, BEELEN, Dietrich, DEVERGIE, Agnes, ALESSANDRINO, Emilio, WILLEMZE, Roel

“…This study was performed to examine the characteristics of transplant activity for patients with myelodysplastic syndromes (MDS) older than 50 years within the…”
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Daunorubicin Versus Mitoxantrone Versus Idarubicin As Induction and Consolidation Chemotherapy for Adults With Acute Myeloid Leukemia: The EORTC and GIMEMA Groups Study AML-10 by MANDELLI, Franco, VIGNETTI, Marco, THOMAS, Xavier, DI RAIMONDO, Francesco, WILLEMZE, Roel, LISO, Vincenzo, FERRARA, Felicetto, BAILA, Liliana, FAZI, Paola, ZITTOUN, Robert, AMADORI, Sergio, DE WITTE, Theo, SUCIU, Stefan, STASI, Roberto, PETTI, Maria-Concetta, MELONI, Giovanna, MUUS, Petra, MARMONT, Filippo, MARIE, Jean-Pierre, LABAR, Boris

“…To compare the antitumor efficacy of three different anthracyclines in combination with cytarabine and etoposide in adult patients with newly diagnosed acute…”
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Sequential Combination of Gemtuzumab Ozogamicin and Standard Chemotherapy in Older Patients With Newly Diagnosed Acute Myeloid Leukemia: Results of a Randomized Phase III Trial by the EORTC and GIMEMA Consortium (AML-17) by AMADORI, Sergio, SUCIU, Stefan, THOMAS, Xavier, LATAGLIATA, Roberto, HALKES, Constantijn J. M, FALZETTI, Franca, MAGRO, Domenico, GUIMARAES, José E, BERNEMAN, Zwi, SPECCHIA, Giorgina, KARRASCH, Matthias, FAZI, Paola, STASI, Roberto, VIGNETTI, Marco, WILLEMZE, Roel, DE WITTE, Theo, MARIE, Jean-Pierre, SALIH, Helmut R, SELLESLAG, Dominik, MUUS, Petra, DE FABRITIIS, Paolo, VENDITTI, Adriano, HO, Anthony D, LÜBBERT, Michael

“…This randomized trial evaluated the efficacy and toxicity of sequential gemtuzumab ozogamicin (GO) and standard chemotherapy in older patients with newly…”
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Long-term follow-up of a trial comparing post-remission treatment with autologous or allogeneic bone marrow transplantation or intensive chemotherapy in younger acute myeloid leukemia patients by Baron, Frédéric, Efficace, Fabio, Cannella, Laura, Willemze, Roel, Vignetti, Marco, Muus, Petra, Marie, Jean-Pierre, Ferrero, Dario, Fazi, Paola, La Sala, Edoardo, Bourhis, Jean-Henri, Fabbiano, Francesco, Bosi, Alberto, Sborgia, Marco, Martinelli, Giovanni, Wittnebel, Sebastian, Trisolini, Silvia, Petti, Maria Concetta, Halkes, Constantijn J M, van der Velden, Walter J F M, de Witte, Theo, Amadori, Sergio, Zittoun, Robert A, Suciu, Stefan

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Allogeneic Stem-Cell Transplantation in Patients With Waldenström Macroglobulinemia: Report From the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation by KYRIAKOU, Charalampia, CANALS, Carmen, SCHATTENBERG, Anton, HAROUSSEAU, Jean-Luc, SUREDA, Anna, SCHMITZ, Norbert, CORNELISSEN, Jan J, SOCIE, Gerard, WILLEMZE, Roel, IFRAH, Norbert, GREINIX, Hildegard T, BLAISE, Didier, DECONINCK, Eric, FERRANT, Augustin

“…Allogeneic stem-cell transplantation (alloSCT) is a curative therapeutic option for patients with low-grade lymphoid malignancies. Information regarding…”
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Retroviral transfer of human CD20 as a suicide gene for adoptive T-cell therapy by Griffioen, Marieke, van Egmond, Esther H.M, Kester, Michel G.D, Willemze, Roel, Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M

“…Laboratory of Experimental Hematology, Leiden University Medical Center, Leiden, The Netherlands Correspondence: Marieke Griffioen, Dept. of Hematology, C2-R,…”
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Hematopoiesis-Restricted Minor Histocompatibility Antigens HA-1- or HA-2-Specific T Cells Can Induce Complete Remissions of Relapsed Leukemia by W. A. Erik Marijt, Mirjam H. M. Heemskerk, Kloosterboer, Freke M., Goulmy, Els, Michel G. D. Kester, Menno A. W. G. van der Hoorn, Simone A. P. van Luxemburg-Heys, Hoogeboom, Manja, Mutis, Tuna, Drijfhout, Jan Wouter, van Rood, Jon J., Willemze, Roel, J. H. Frederik Falkenburg

“…Donor lymphocyte infusion (DLI) into patients with a relapse of their leukemia or multiple myeloma after allogeneic stem cell transplantation (alloSCT) has…”
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Higher Incidence of Relapse With Peripheral Blood Rather Than Marrow As a Source of Stem Cells in Adults With Acute Myelocytic Leukemia Autografted During the First Remission by GORIN, Norbert-Claude, LABOPIN, Myriam, FOUILLARD, Loic, WILLEMZE, Roel, ROCHA, Vanderson, BLAISE, Didier, REIFFERS, Josy, MELONI, Giovanna, MICHALLET, Mauricette, DE WITTE, Theo, ATTAL, Michel, RIO, Bernard, WITZ, Francois

“…The cell source for autologous stem cell transplantation has shifted from bone marrow (BM) to peripheral blood (PB). In acute myelocytic leukemia (AML), for…”
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Generation and administration of HA-1-specific T-cell lines for the treatment of patients with relapsed leukemia after allogeneic stem cell transplantation: a pilot study by MEIJ, Pauline, JEDEMA, Inge, DER HOORN, Menno A. W. G. Van, BONGAERTS, Rian, COX, Linda, WAFELMAN, Amon R, MARIJT, Erik W. A, WILLEMZE, Roel, FREDERIK FALKENBURG, J. H

“…Since HA-1-specific T cells have been shown to make a significant contribution to the clinical responses in patients with relapsed leukemia, we investigated…”
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Identical Outcome After Autologous or Allogeneic Genoidentical Hematopoietic Stem-Cell Transplantation in First Remission of Acute Myelocytic Leukemia Carrying Inversion 16 or t(8;21): A Retrospective Study From the European Cooperative Group for Blood and Marrow Transplantation by GORIN, Norbert-Claude, LABOPIN, Myriam, DECONNINCK, Eric, HAROUSSEAU, Jean-Luc, POLGE, Emmanuelle, ROCHA, Vanderson, FRASSONI, Francesco, MILPIED, Noel, ATTAL, Michel, BLAISE, Didier, MELONI, Giovanna, IORI, Anna P, MICHALLET, Mauricette, WILLEMZE, Roel

“…Patients with acute myelocytic leukemia carrying inversion 16 (inv16) or t(8;21) have a better initial response to high-dose cytarabine than patients without…”
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Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection by ZANDVLIET, Maarten L, FREDERIK FALKENBURG, J. H, GUCHELAAR, Henk-Jan, SCHILHAM, Marco W, MEIJ, Pauline, VAN LIEMPT, Ellis, VELTROP-DUITS, Louise A, LANKESTER, Arjan C, KALPOE, Jayant S, KESTER, Michel G. D, VAN DER STEEN, Dirk M, VAN TOL, Maarten J, WILLEMZE, Roel

“…Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of…”
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Minor histocompatibility antigens in human stem cell transplantation by Falkenburg, J.H.Frederik, van de Corput, Lisette, Marijt, Erik W.A, Willemze, Roel

“…Minor histocompatibility antigens (mHags) play a major role in graft rejection, the induction of detrimental graft-vs-host disease (GVHD), and the development…”
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Long-term mixed chimerism after immunologic conditioning and MHC-mismatched stem-cell transplantation is dependent on NK-cell tolerance by Westerhuis, Geert, Maas, Wendy G.E., Willemze, Roel, Toes, René E.M., Fibbe, Willem E.

“…T-cell tolerance is mandatory for major histocompatibility complex (MHC)-mismatched stem-cell transplantation without cytoreduction. Here, we used a…”
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Identification of phosphatidylinositol 4-kinase type II β as HLA class II-restricted target in graft versus leukemia reactivity by Griffioen, Marieke, van der Meijden, Edith D, Slager, Elisabeth H, Honders, M. Willy, Rutten, Caroline E, van Luxemburg-Heijs, Simone A.P, von dem Borne, Peter A, van Rood, Johannes J, Willemze, Roel, Falkenburg, J.H. Frederik

“…Patients with hematological malignancies can be successfully treated with HLA-matched T cell-depleted allogeneic stem cell transplantation (alloSCT) and…”
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Is there an impact of killer cell immunoglobulin-like receptors and KIR-ligand incompatibilities on outcomes after unrelated cord blood stem cell transplantation? by Willemze, Roel, MD, Ruggeri, Annalisa, MD, Purtill, Duncan, MD, Rodrigues, Celso Arrais, MD, Gluckman, Eliane, MD, Rocha, Vanderson

“…Donor killer cell immunoglobulin-like receptor (KIR) ligand incompatibility in the graft-versus-host direction is associated with decreased relapse incidence…”
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The Polycomb group protein EZH2 is upregulated in proliferating, cultured human mantle cell lymphoma by Visser, Hein P. J., Gunster, Marco J., Kluin‐Nelemans, Hanneke C., Manders, Erik M. M., Raaphorst, Frank M., Meijer, Chris J. L. M., Willemze, Roel, Otte, Arie P.

“…Polycomb group (PcG) proteins are involved in the stable transmittance of the repressive state of their gene targets throughout the cell cycle. Mis‐expression…”
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The Treatment of Acute Myeloid Leukemia in First Relapse: A Comprehensive Review of the Literature by Leopold, Lance H., Willemze, Roel

“…Twenty years of published literature was reviewed for chemotherapy regimens used to treat patients with acute myeloid leukemia (AML) in first relapse…”
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Neutrophils Are Indispensable for Hematopoietic Stem Cell Mobilization Induced by Interleukin-8 in Mice by Johannes F. M. Pruijt, Verzaal, Perry, van Os, Ronald, Evert-Jan F. M. de Kruijf, Marianke L. J. van Schie, Mantovani, Alberto, Vecchi, Annunciata, Ivan J. D. Lindley, Willemze, Roel, Starckx, Sofie, Opdenakker, Ghislain, Fibbe, Willem E.

“…The CXC chemokine interleukin-8 (IL-8/CXCL8) induces rapid mobilization of hematopoietic progenitor cells (HPCs). Previously we showed that mobilization could…”
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