Search Results - "WILLCOCKS, Lisa C"

Effect of belimumab on proteinuria and anti-phospholipase A2 receptor autoantibody in primary membranous nephropathy by Barrett, Christine, Willcocks, Lisa C, Jones, Rachel B, Tarzi, Ruth M, Henderson, Robert B, Cai, Gengqian, Gisbert, Sophie I, Belson, Alexandra S, Savage, Caroline O

“…Abstract Background Immunosuppressant drugs reduce proteinuria and anti-phospholipase A2 receptor autoantibodies (PLA2R-Ab) in primary membranous nephropathy…”
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Long-term follow-up of patients who received repeat-dose rituximab as maintenance therapy for ANCA-associated vasculitis by Alberici, Federico, Smith, Rona M, Jones, Rachel B, Roberts, Darren M, Willcocks, Lisa C, Chaudhry, Afzal, Smith, Kenneth G C, Jayne, David R W

“…ANCA-associated vasculitis (AAV) is characterized by a chronic relapsing course. Rituximab (RTX) is an effective maintenance treatment; however, the long-term…”
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Rituximab for maintenance of remission in ANCA-associated vasculitis: expert consensus guidelines by Tieu, Joanna, Smith, Rona, Basu, Neil, Brogan, Paul, D’Cruz, David, Dhaun, Neeraj, Flossmann, Oliver, Harper, Lorraine, Jones, Rachel B, Lanyon, Peter C, Luqmani, Raashid A, McAdoo, Stephen P, Mukhtyar, Chetan, Pearce, Fiona A, Pusey, Charles D, Robson, Joanna C, Salama, Alan D, Smyth, Lucy, Watts, Richard A, Willcocks, Lisa C, Jayne, David R W

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A randomised, two-arm (1:1 ratio), double blind, placebo controlled phase III trial to assess the efficacy, safety, cost and cost-effectiveness of Rituximab in treating de novo or relapsing NS in patients with MCD/FSGS (TURING) by C Willcocks, Lisa, Qian, Wendi, Cader, Ruzaika, Gatley, Katrina, Siddiqui, Hira, Tabebisong, Endurance, Champion, Karlena, Kronbichler, Andreas, Lightstone, Liz, Jayne, David, Wilson, Edward, Griffith, Megan

“…Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS) are a spectrum of disease causing the nephrotic syndrome (NS), characterised by…”
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defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus by Willcocks, Lisa C, Carr, Edward J, Niederer, Heather A, Rayner, Tim F, Williams, Thomas N, Yang, Wanling, Scott, J. Anthony G, Urban, Britta C, Peshu, Norbert, Vyse, Timothy J, Lau, Yu Lung, Lyons, Paul A, Smith, Kenneth G.C

“…Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease more prevalent in people of African and Asian origin than Caucasian origin. FcγRIIb is…”
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Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils by McGovern, Naomi N, Cowburn, Andrew S, Porter, Linsey, Walmsley, Sarah R, Summers, Charlotte, Thompson, Alfred A R, Anwar, Sadia, Willcocks, Lisa C, Whyte, Moira K B, Condliffe, Alison M, Chilvers, Edwin R

“…Neutrophils play a central role in the innate immune response and a critical role in bacterial killing. Most studies of neutrophil function have been conducted…”
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The immunopathology of ANCA-associated vasculitis by McKinney, Eoin F., Willcocks, Lisa C., Broecker, Verena, Smith, Kenneth G. C.

“…The small-vessel vasculitides are a group of disorders characterised by variable patterns of small blood vessel inflammation producing a markedly heterogeneous…”
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Association of a TNFSF13B (BAFF) regulatory region single nucleotide polymorphism with response to rituximab in antineutrophil cytoplasmic antibody–associated vasculitis by Alberici, Federico, MD, Smith, Rona M., MD, Fonseca, Mariana, PhD, Willcocks, Lisa C., PhD, Jones, Rachel B., MD, Holle, Julia U., PhD, Wieczorek, Stefan, MD, Neumann, Thomas, PhD, Martorana, Davide, PhD, Gregorini, Gina, MD, Sinico, Renato A., MD, Bruchfeld, Annette, PhD, Gunnarsson, Iva, PhD, Ohlsson, Sophie, PhD, Baslund, Bo, PhD, Tesar, Vladimir, PhD, Hruskova, Zdenka, PhD, Cid, Maria C., PhD, Vaglio, Augusto, PhD, Lyons, Paul A., PhD, Smith, Kenneth G.C., PhD, Jayne, David R.W., MD

“…To the Editor: Rituximab is effective at inducing and maintaining remission in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).1,2 The…”
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The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis by WILLCOCKS, Lisa C, LYONS, Paul A, REES, Andrew J, SMITH, Kenneth Gc

“…The aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis has not been well defined. Here we review two factors which may…”
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Genetic susceptibility to systemic lupus erythematosus protects against cerebral malaria in mice by Waisberg, Michael, Tarasenko, Tatyana, Vickers, Brandi K., Scott, Bethany L., Willcocks, Lisa C., Molina-Cruz, Alvaro, Pierce, Matthew A., Huang, Chiung-yu, Torres-Velez, Fernando J., Smith, Kenneth G. C., Barillas-Mury, Carolina, Miller, Louis H., Pierce, Susan K., Bolland, Silvia

“…Plasmodium falciparum has exerted tremendous selective pressure on genes that improve survival in severe malarial infections. Systemic lupus erythematosus…”
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Cryoglobulinaemic vasculitis diagnostic and treatment recommendations by Nelveg-Kristensen, Karl Emil, Paterson, Anna, Willcocks, Lisa C

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Extracorporeal membrane oxygenation for life-threatening ANCA-associated vasculitis with pulmonary haemorrhage by McClure, Mark E, Smith, Rona M, Sivasothy, Pasupathy, Willcocks, Lisa C

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Avacopan for ANCA-associated vasculitis – information for prescribers by McGovern, Dominic, Jones, Rachel B, Willcocks, Lisa C, Smith, Rona M, Jayne, David R W, Kronbichler, Andreas

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A CD8 + T cell transcription signature predicts prognosis in autoimmune disease by Lyons, Paul A, Smith, Kenneth G C, McKinney, Eoin F, Carr, Edward J, Hollis, Jane L, Jayne, David R W, Willcocks, Lisa C, Koukoulaki, Maria, Brazma, Alvis, Jovanovic, Vojislav, Kemeny, D Michael, Pollard, Andrew J, MacAry, Paul A, Chaudhry, Afzal N

“…Autoimmune diseases are common and debilitating, but their severe manifestations could be reduced if biomarkers were available to allow individual tailoring of…”
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Ear, nose, throat and airways disease in granulomatosis with polyangiitis by Coates, Matthew L, Willcocks, Lisa C, Sivasothy, Pasupathy, Martinez Del Pero, Marcos

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Management of adult patients with podocytopathies: an update from the ERA Immunonephrology Working Group by Mirioglu, Safak, Daniel-Fischer, Lisa, Berke, Ilay, Ahmad, Syed Hasan, Bajema, Ingeborg M, Bruchfeld, Annette, Fernandez-Juarez, Gema M, Floege, Jürgen, Frangou, Eleni, Goumenos, Dimitrios, Griffith, Megan, Moran, Sarah M, van Kooten, Cees, Steiger, Stefanie, Stevens, Kate I, Turkmen, Kultigin, Willcocks, Lisa C, Kronbichler, Andreas

“…ABSTRACT The histopathological lesions, minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are entities without immune complex deposits…”
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Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake by Willcocks, Lisa C, Lyons, Paul A, Clatworthy, Menna R, Robinson, James I, Yang, Wanling, Newland, Stephen A, Plagnol, Vincent, McGovern, Naomi N, Condliffe, Alison M, Chilvers, Edwin R, Adu, Dwomoa, Jolly, Elaine C, Watts, Richard, Lau, Yu Lung, Morgan, Ann W, Nash, Gerard, Smith, Kenneth G C

“…Copy number (CN) variation (CNV) has been shown to be common in regions of the genome coding for immune-related genes, and thus impacts upon polygenic…”
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Rituximab for maintenance of remission in ANCA-associated vasculitis: expert consensus guidelines—Executive summary by Tieu, Joanna, Smith, Rona, Basu, Neil, Brogan, Paul, D’Cruz, David, Dhaun, Neeraj, Flossmann, Oliver, Harper, Lorraine, Jones, Rachel B, Lanyon, Peter C, Luqmani, Raashid A, McAdoo, Stephen P, Mukhtyar, Chetan, Pearce, Fiona A, Pusey, Charles D, Robson, Joanna C, Salama, Alan D, Smyth, Lucy, Watts, Richard A, Willcocks, Lisa C, Jayne, David R W

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Defunctioning Polymorphism in the Immunoglobulin G Inhibitory Receptor (FcγRIIB-T/T232) Does not Impact on Kidney Transplant or Recipient Survival by Clatworthy, Menna R, Matthews, Rebeccah J, Doehler, Bernd, Willcocks, Lisa C, Opelz, Gerhard, Smith, Kenneth G.C

“…BACKGROUNDThere is an increasing appreciation of the deleterious effects of antibody and B cells on acute and chronic transplant outcomes. Many effector…”
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Successful outcome using bortezomib in adult refractory IgA vasculitis: a case report by Van de Perre, Els, Smith, Rona M, Bardsley, Victoria, Crawley, Charles, Willcocks, Lisa C, Jayne, David R W

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