Search Results - "WILLAN, Andrew"

Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis by Freedman, Stephen B, Williamson-Urquhart, Sarah, Farion, Ken J, Gouin, Serge, Willan, Andrew R, Poonai, Naveen, Hurley, Katrina, Sherman, Philip M, Finkelstein, Yaron, Lee, Bonita E, Pang, Xiao-Li, Chui, Linda, Schnadower, David, Xie, Jianling, Gorelick, Marc, Schuh, Suzanne

“…Restoring intestinal flora may improve outcomes in children with acute gastroenteritis. In this multicenter trial, the administration of lactobacillus for 5…”
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A Randomized Trial of Planned Cesarean or Vaginal Delivery for Twin Pregnancy by Barrett, Jon F.R, Hannah, Mary E, Hutton, Eileen K, Willan, Andrew R, Allen, Alexander C, Armson, B. Anthony, Gafni, Amiram, Joseph, K.S, Mason, Dalah, Ohlsson, Arne, Ross, Susan, Sanchez, J. Johanna, Asztalos, Elizabeth V

“…In this randomized trial comparing delivery strategies in women with twin gestation, planned cesarean section did not significantly increase or decrease the…”
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Effect of Dilute Apple Juice and Preferred Fluids vs Electrolyte Maintenance Solution on Treatment Failure Among Children With Mild Gastroenteritis: A Randomized Clinical Trial by Freedman, Stephen B, Willan, Andrew R, Boutis, Kathy, Schuh, Suzanne

“…IMPORTANCE: Gastroenteritis is a common pediatric illness. Electrolyte maintenance solution is recommended to treat and prevent dehydration. Its advantage in…”
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Bayesian methods for pilot studies by Willan, Andrew R, Thabane, Lehana

“…Background/aims: The use of pilot studies to help inform the design of randomized controlled trials has increased significantly over the last couple of…”
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Effectiveness of Structured Care Coordination for Children With Medical Complexity: The Complex Care for Kids Ontario (CCKO) Randomized Clinical Trial by Cohen, Eyal, Quartarone, Samantha, Orkin, Julia, Moretti, Myla E, Emdin, Abby, Guttmann, Astrid, Willan, Andrew R, Major, Nathalie, Lim, Audrey, Diaz, Sanober, Osqui, Lisa, Soscia, Joanna, Fu, Longdi, Gandhi, Sima, Heath, Anna, Fayed, Nora

“…Children with medical complexity (CMC) have chronic conditions and high health needs and may experience fragmented care. To compare the effectiveness of a…”
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Effect of Oximetry on Hospitalization in Bronchiolitis: A Randomized Clinical Trial by Schuh, Suzanne, Freedman, Stephen, Coates, Allan, Allen, Upton, Parkin, Patricia C, Stephens, Derek, Ungar, Wendy, DaSilva, Zelia, Willan, Andrew R

“…IMPORTANCE: Routine use of pulse oximetry has been associated with changes in bronchiolitis management and may have lowered the hospitalization threshold for…”
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Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth by Roth, Daniel E, Morris, Shaun K, Zlotkin, Stanley, Gernand, Alison D, Ahmed, Tahmeed, Shanta, Shaila S, Papp, Eszter, Korsiak, Jill, Shi, Joy, Islam, M. Munirul, Jahan, Ishrat, Keya, Farhana K, Willan, Andrew R, Weksberg, Rosanna, Mohsin, Minhazul, Rahman, Qazi S, Shah, Prakesh S, Murphy, Kellie E, Stimec, Jennifer, Pell, Lisa G, Qamar, Huma, Al Mahmud, Abdullah

“…In this double-blind, randomized trial in Bangladesh, maternal vitamin D supplementation from midpregnancy until birth or 6 months post partum did not improve…”
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Effect of a Pediatric Early Warning System on All-Cause Mortality in Hospitalized Pediatric Patients: The EPOCH Randomized Clinical Trial by Parshuram, Christopher S, Dryden-Palmer, Karen, Farrell, Catherine, Gottesman, Ronald, Gray, Martin, Hutchison, James S, Helfaer, Mark, Hunt, Elizabeth A, Joffe, Ari R, Lacroix, Jacques, Moga, Michael Alice, Nadkarni, Vinay, Ninis, Nelly, Parkin, Patricia C, Wensley, David, Willan, Andrew R, Tomlinson, George A

“…IMPORTANCE: There is limited evidence that the use of severity of illness scores in pediatric patients can facilitate timely admission to the intensive care…”
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The Value of Value of Information: Best Informing Research Design and Prioritization Using Current Methods by Eckermann, Simon, Karnon, Jon, Willan, Andrew R.

“…Value of information (VOI) methods have been proposed as a systematic approach to inform optimal research design and prioritization. Four related questions…”
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Active Lives South Australia health economic analysis: an evidence base for the potential of health promotion strategies supporting physical activity guidelines to reduce public health costs while improving wellbeing by Eckermann, Simon, Willan, Andrew R.

“…Aim The COVID-19 pandemic has threatened individual and population wellbeing and strategies to jointly address these challenges within budget constraints are…”
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Optimal clinical trial design using value of information methods with imperfect implementation by Willan, Andrew R., Eckermann, Simon

“…Traditional sample size calculations for randomized clinical trials are based on the tests of hypotheses and depend on somewhat arbitrarily chosen factors,…”
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Expected value of information and decision making in HTA by Eckermann, Simon, Willan, Andrew R.

“…Decision makers within a jurisdiction facing evidence of positive but uncertain incremental net benefit of a new health care intervention have viable options…”
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Multiple courses of antenatal corticosteroids for preterm birth (MACS): a randomised controlled trial by Murphy, Kellie E, Dr, Hannah, Mary E, Prof, Willan, Andrew R, Prof, Hewson, Sheila A, BA, Ohlsson, Arne, Prof, Kelly, Edmond N, MB, Matthews, Stephen G, Prof, Saigal, Saroj, Prof, Asztalos, Elizabeth, MD, Ross, Susan, Prof, Delisle, Marie-France, MD, Amankwah, Kofi, Prof, Guselle, Patricia, MSc, Gafni, Amiram, Prof, Lee, Shoo K, Prof, Armson, B Anthony, Prof

“…Summary Background One course of antenatal corticosteroids reduces the risk of respiratory distress syndrome and neonatal death. Weekly doses given to women…”
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Accounting for treatment by center interaction in sample size determinations and the use of surrogate outcomes in the pessary for the prevention of preterm birth trial: a simulation study by Willan, Andrew R

“…The Pessary for the Prevention of Preterm Birth Study (PS3) is an international, multicenter, randomized clinical trial designed to examine the effectiveness…”
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Presenting Evidence and Summary Measures to Best Inform Societal Decisions When Comparing Multiple Strategies by Eckermann, Simon, Willan, Andrew R.

“…Multiple strategy comparisons in health technology assessment (HTA) are becoming increasingly important, with multiple alternative therapeutic actions,…”
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Intermittent vs Continuous Pulse Oximetry in Hospitalized Infants With Stabilized Bronchiolitis: A Randomized Clinical Trial by Mahant, Sanjay, Wahi, Gita, Bayliss, Ann, Giglia, Lucy, Kanani, Ronik, Pound, Catherine M, Sakran, Mahmoud, Kozlowski, Natascha, Breen-Reid, Karen, Arafeh, Dana, Moretti, Myla E, Agarwal, Amisha, Barrowman, Nick, Willan, Andrew R, Schuh, Suzanne, Parkin, Patricia C

“…There is low level of evidence and substantial practice variation regarding the use of intermittent or continuous monitoring in infants hospitalized with…”
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Multiple courses of antenatal corticosteroids for preterm birth study: outcomes in children at 5 years of age (MACS-5) by Asztalos, Elizabeth V, Murphy, Kellie E, Willan, Andrew R, Matthews, Stephen G, Ohlsson, Arne, Saigal, Saroj, Armson, B Anthony, Kelly, Edmond N, Delisle, Marie-France, Gafni, Amiram, Lee, Shoo K, Sananes, Renee, Rovet, Joanne, Guselle, Patricia, Amankwah, Kofi, Saleem, Mariam, Sanchez, Johanna

“…A single course of antenatal corticosteroid therapy is recommended for pregnant women at risk of preterm birth between 24 and 33 weeks' gestational age…”
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Effect of Nebulized Magnesium vs Placebo Added to Albuterol on Hospitalization Among Children With Refractory Acute Asthma Treated in the Emergency Department: A Randomized Clinical Trial by Schuh, Suzanne, Sweeney, Judy, Rumantir, Maggie, Coates, Allan L, Willan, Andrew R, Stephens, Derek, Atenafu, Eshetu G, Finkelstein, Yaron, Thompson, Graham, Zemek, Roger, Plint, Amy C, Gravel, Jocelyn, Ducharme, Francine M, Johnson, David W, Black, Karen, Curtis, Sarah, Beer, Darcy, Klassen, Terry P, Nicksy, Darcy, Freedman, Stephen B

“…IMPORTANCE: While intravenous magnesium decreases hospitalizations in refractory pediatric acute asthma, it is variably used because of invasiveness and safety…”
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Expected Value of Sample Information with Imperfect Implementation: Improving Practice and Reducing Uncertainty with Appropriate Counterfactual Consideration by Eckermann, Simon, Willan, Andrew R.

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Sample Size Determination for Cost-Effectiveness Trials by Willan, Andrew R.

“…Methods for determining sample size requirements for cost-effectiveness studies are reviewed and illustrated. Traditional methods based on tests of hypothesis…”
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