Search Results - "WIKLUND, HELENA"

SUMO‐modified insulin‐like growth factor 1 receptor (IGF‐1R) increases cell cycle progression and cell proliferation by Lin, Yingbo, Liu, Hongyu, Waraky, Ahmed, Haglund, Felix, Agarwal, Prasoon, Jernberg‐Wiklund, Helena, Warsito, Dudi, Larsson, Olle

“…Increasing number of studies have shown nuclear localization of the insulin‐like growth factor 1 receptor (nIGF‐1R) in tumor cells and its links to adverse…”
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PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma by Nylund, Patrick, Garrido-Zabala, Berta, Párraga, Alba Atienza, Vasquez, Louella, Pyl, Paul Theodor, Harinck, George Mickhael, Ma, Anqi, Jin, Jian, Öberg, Fredrik, Kalushkova, Antonia, Wiklund, Helena Jernberg

“…Multiple myeloma is a heterogeneous hematological disease that originates from the bone marrow and is characterized by the monoclonal expansion of malignant…”
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Phylogeny of scale-worms (Aphroditiformia, Annelida), assessed from 18SrRNA, 28SrRNA, 16SrRNA, mitochondrial cytochrome c oxidase subunit I (COI), and morphology by Norlinder, Erika, Nygren, Arne, Wiklund, Helena, Pleijel, Fredrik

“…[Display omitted] ► The phylogeny of scale-worms (Annelida) is assessed from combined analyses of snuclear, mitochondrial, and morphological data. ►…”
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Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40 by Wenthe, Jessica, Naseri, Sedigheh, Hellström, Ann-Charlotte, Wiklund, Helena Jernberg, Eriksson, Emma, Loskog, Angelica

“…Multiple myeloma (MM) is a plasma cell malignancy that is characterized by immune dysregulation. MM is commonly treated with immunomodulating agents, but still…”
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Managing a sustainable deep-sea 'blue economy' requires knowledge of what actually lives there by Glover, Adrian G, Wiklund, Helena, Chen, Chong, Dahlgren, Thomas G

“…Ensuring that the wealth of resources contained in our oceans are managed and developed in a sustainable manner is a priority for the emerging 'blue economy'…”
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The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma by Nylund, Patrick, Garrido-Zabala, Berta, Kalushkova, Antonia, Wiklund, Helena Jernberg

“…Extensive genome-wide sequencing efforts have unveiled the intricate regulatory potential of long non-protein coding RNAs (lncRNAs) within the domain of…”
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A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma by Nylund, Patrick, Atienza Párraga, Alba, Haglöf, Jakob, De Bruyne, Elke, Menu, Eline, Garrido-Zabala, Berta, Ma, Anqi, Jin, Jian, Öberg, Fredrik, Vanderkerken, Karin, Kalushkova, Antonia, Jernberg-Wiklund, Helena

“…Multiple myeloma (MM) is a heterogeneous haematological disease that remains clinically challenging. Increased activity of the epigenetic silencer EZH2 is a…”
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DNA barcoding uncovers cryptic diversity in 50% of deep-sea Antarctic polychaetes by Brasier, Madeleine J., Wiklund, Helena, Neal, Lenka, Jeffreys, Rachel, Linse, Katrin, Ruhl, Henry, Glover, Adrian G.

“…The Antarctic marine environment is a diverse ecosystem currently experiencing some of the fastest rates of climatic change. The documentation and management…”
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A Role for the Chromatin-Remodeling Factor BAZ1A in Neurodevelopment by Zaghlool, Ammar, Halvardson, Jonatan, Zhao, Jin J., Etemadikhah, Mitra, Kalushkova, Antonia, Konska, Katarzyna, Jernberg-Wiklund, Helena, Thuresson, Ann-Charlotte, Feuk, Lars

“…ABSTRACT Chromatin‐remodeling factors are required for a wide range of cellular and biological processes including development and cognition, mainly by…”
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High diversity and pan-oceanic distribution of deep-sea polychaetes: Prionospio and Aurospio (Annelida: Spionidae) in the Atlantic and Pacific Ocean by Guggolz, Theresa, Meißner, Karin, Schwentner, Martin, Dahlgren, Thomas G., Wiklund, Helena, Bonifácio, Paulo, Brandt, Angelika

“…Prionospio Malmgren 1867 and Aurospio Maciolek 1981 (Annelida: Spionidae) are polychaete genera commonly found in the deep sea. Both genera belong to the…”
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Growth signals employ CGGBP1 to suppress transcription of Alu-SINEs by Agarwal, Prasoon, Enroth, Stefan, Teichmann, Martin, Jernberg Wiklund, Helena, Smit, Arian, Westermark, Bengt, Singh, Umashankar

“…CGGBP1 (CGG triplet repeat-binding protein 1) regulates cell proliferation, stress response, cytokinesis, telomeric integrity and transcription. It could…”
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Genetic connectivity from the Arctic to the Antarctic: Sclerolinum contortum and Nicomache lokii (Annelida) are both widespread in reducing environments by Eilertsen, Mari H., Georgieva, Magdalena N., Kongsrud, Jon A., Linse, Katrin, Wiklund, Helena, Glover, Adrian G., Rapp, Hans T.

“…The paradigm of large geographic ranges in the deep sea has been challenged by genetic studies, which often reveal putatively widespread species to be several…”
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A new species of Raricirrus (Annelida: Cirratuliformia) from deep-water sunken wood off California by Magalhães, Wagner F, Linse, Katrin, Wiklund, Helena

“…The genus Raricirrus is characterized by the absence of feeding palps, presence of filamentous branchiae, posterior segments shorter and wider than preceding…”
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The Current State of Eunicida (Annelida) Systematics and Biodiversity by Zanol, Joana, Carrera-Parra, Luis F., Steiner, Tatiana Menchini, Amaral, Antonia Cecilia Z., Wiklund, Helena, Ravara, Ascensão, Budaeva, Nataliya

“…In this study, we analyze the current state of knowledge on extant Eunicida systematics, morphology, feeding, life history, habitat, ecology, distribution…”
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EZH2 inhibition in multiple myeloma downregulates myeloma associated oncogenes and upregulates microRNAs with potential tumor suppressor functions by Alzrigat, Mohammad, Párraga, Alba Atienza, Agarwal, Prasoon, Zureigat, Hadil, Österborg, Anders, Nahi, Hareth, Ma, Anqi, Jin, Jian, Nilsson, Kenneth, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena

“…Multiple Myeloma (MM) is a plasma cell tumor localized to the bone marrow (BM). Despite the fact that current treatment strategies have improved patients'…”
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One Omics Approach Does Not Rule Them All: The Metabolome and the Epigenome Join Forces in Haematological Malignancies by Kalushkova, Antonia, Nylund, Patrick, Párraga, Alba Atienza, Lennartsson, Andreas, Jernberg-Wiklund, Helena

“…Aberrant DNA methylation, dysregulation of chromatin-modifying enzymes, and microRNAs (miRNAs) play a crucial role in haematological malignancies. These…”
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Abyssal fauna of polymetallic nodule exploration areas, eastern Clarion-Clipperton Zone, central Pacific Ocean: Annelida: Capitellidae, Opheliidae, Scalibregmatidae, and Travisiidae by Wiklund, Helena, Neal, Lenka, Glover, Adrian G, Drennan, Regan, Muriel Rabone, Dahlgren, Thomas G

“…We present DNA taxonomy of abyssal polychaete worms from the eastern Clarion-Clipperton Zone (CCZ), central Pacific Ocean, using material collected as part of…”
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Targeting EZH2 in Multiple Myeloma-Multifaceted Anti-Tumor Activity by Alzrigat, Mohammad, Jernberg-Wiklund, Helena, Licht, Jonathan D

“…The enhancer of zeste homolog 2 (EZH2) is the enzymatic subunit of the polycomb repressive complex 2 (PRC2) that exerts important functions during normal…”
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Abyssal fauna of polymetallic nodule exploration areas, eastern Clarion-Clipperton Zone, central Pacific Ocean: Amphinomidae and Euphrosinidae (Annelida, Amphinomida) by Neal, Lenka, Wiklund, Helena, Gunton, Laetitia M, Rabone, Muriel, Bribiesca-Contreras, Guadalupe, Dahlgren, Thomas G, Glover, Adrian G

“…This is a contribution in a series of taxonomic publications on benthic fauna of polymetallic nodule fields in the eastern abyssal Clarion-Clipperton Zone…”
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The discovery of a natural whale fall in the Antarctic deep sea by Amon, Diva J., Glover, Adrian G., Wiklund, Helena, Marsh, Leigh, Linse, Katrin, Rogers, Alex D., Copley, Jonathan T.

“…Large cetacean carcasses at the deep-sea floor, known as ‘whale falls’, provide a resource for generalist-scavenging species, chemosynthetic fauna related to…”
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