Search Results - "WIENER, ERIK C"

ZD6474, a multitargeted inhibitor for receptor tyrosine kinases, suppresses growth of gliomas expressing an epidermal growth factor receptor mutant, EGFRvIII, in the brain by Yiin, Jia-Jean, Hu, Bo, Schornack, Paul A, Sengar, Raghvendra S, Liu, Kun-Wei, Feng, Haizhong, Lieberman, Frank S, Chiou, Shih-Hwa, Sarkaria, Jann N, Wiener, Erik C, Ma, Hsin-I, Cheng, Shi-Yuan

“…Epidermal growth factor receptor (EGFR) vIII is a mutated EGFR that is frequently overexpressed in glioblastomas and implicated in response to receptor…”
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Comparison of tumor histology to dynamic contrast enhanced magnetic resonance imaging-based physiological estimates by Aref, Michael, Chaudhari, Amir R, Bailey, Keith L, Aref, Susanne, Wiener, Erik C

“…Abstract Purpose The purpose of this study was to compare histologically determined cellularity and extracellular space to dynamic contrast-enhanced magnetic…”
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Azide Tripodal Dendrons from Behera’s Amine and Their Clicked Dendrimers by Barmare, Farhana, Abadjian, Marie-Caline Z., Wiener, Erik C., Grotjahn, Douglas B.

“…Diazo transfer reactions on Behera’s amine and its next-generation analogue formed G0 and G1 azide dendrons bearing three and nine tert-butyl-protected esters,…”
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Bifunctional Chelates Optimized for Molecular MRI by Wiener, Erik C, Abadjian, Marie-Caline, Sengar, Raghvendra, Vander Elst, Luce, Van Niekerk, Christoffel, Grotjahn, Douglas B, Leung, Po Yee, Schulte, Christie, Moore, Curtis E, Rheingold, Arnold L

“…Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) include an effective concentration of paramagnetic or…”
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Combined imaging biomarkers for therapy evaluation in glioblastoma multiforme: correlating sodium MRI and F-18 FLT PET on a voxel-wise basis by Laymon, Charles M, Oborski, Matthew J, Lee, Vincent K, Davis, Denise K, Wiener, Erik C, Lieberman, Frank S, Boada, Fernando E, Mountz, James M

“…Abstract We evaluate novel magnetic resonance imaging (MRI) and positron emission tomography (PET) quantitative imaging biomarkers and associated…”
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A Fluorinated Dendrimer-Based Nanotechnology Platform: New Contrast Agents for High Field Imaging by Huang, Zhihua, Sengar, Raghvendra S, Nigam, Archana, Abadjian, Marie-Caline, Potter, Douglas M, Grotjahn, Douglas B, Wiener, Erik C

“…OBJECTIVES:We aimed to develop a directly detected magnetic resonance imaging (MRI) contrast agent for use with high fields based on a nanoscale fluorinated…”
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Magnetic resonance imaging-guided adoptive cellular immunotherapy of central nervous system tumors with a T1 contrast agent by Sengar, Raghvendra S., Spokauskiene, Laima, Steed, Daniel P., Griffin, Patricia, Arbujas, Norma, Chambers, William H., Wiener, Erik C.

“…Dendritic cells (DCs) are the most effective antigen‐presenting cells (APCs) and are used in a variety of immunotherapeutic approaches. Adoptive cellular…”
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Characteristics of a New MRI Contrast Agent Prepared From Polypropyleneimine Dendrimers, Generation 2 by Wang, Steven J, Brechbiel, Martin, Wiener, Erik C

“…RATIONALE AND OBJECTIVES:Dendrimer-based magnetic resonance imaging (MRI) contrast agents offer many advantages including high levels of amplification. The…”
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Targeting Dendrimer-Chelates to Tumors and Tumor Cells Expressing the High-Affinity Folate Receptor by WIENER, ERIK C, KONDA, SHEELA, SHADRON, AMBER, BRECHBIEL, MARTIN, GANSOW, OTTO

“…RATIONALE AND OBJECTIVESThe authors developed a new method for delivering contrast agents to tumors and tumor cells. Gadolinium complexes of folate-conjugated…”
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Development of a Tumor-Targeting MR Contrast Agent Using the High-Affinity Folate Receptor: Work in Progress by KONDA, SHEELA D, AREF, MICHAEL, BRECHBIEL, MARTIN, WIENER, ERIK C

“…Konda SD, Aref M, Brechbiel M, Wiener EC. Development of a tumor-targeting MR contrast agent using the high-affinity folate receptorWork in progress. Invest…”
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Tri-tert-butyl 3-oxo-4-oxa-1,8,11-triazaspiro[5.6]dodecane-1,8,11-triacetate by Sengar, Raghvendra Singh, Geib, Steven J., Nigam, Archana, Wiener, Erik C.

“…The title compound, C26H45N3O8, is a bicyclic molecule; the seven‐membered diazepane ring has a twisted‐chair conformation and the six‐membered morpholine ring…”
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Spatial and temporal resolution effects on dynamic contrast-enhanced magnetic resonance mammography by Aref, Michael, Handbury, Josh D, Xiuquan Ji, Jim, Aref, Susanne, Wiener, Erik C

“…Abstract We tested the hypothesis that partial volume effects due to poor in-plane resolution and/or low temporal resolution used in clinical dynamic…”
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Identifying Tumor Vascular Permeability Heterogeneity With Magnetic Resonance Imaging Contrast Agents by AREF, MICHAEL, BRECHBIEL, MARTIN, WIENER, ERIK C

“…Aref M, Brechbiel M, Wiener E. Identifying tumor vascular permeability heterogeneity with magnetic resonance imaging contrast agents. Invest Radiol…”
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Imaging folate binding protein expression with MRI by Wiener, Erik C, Konda, Sheela D, Wang, Steven, Brechbiel, Martin

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Biodistribution of a 153Gd-Folate Dendrimer, Generation = 4, in Mice With Folate-Receptor Positive and Negative Ovarian Tumor Xenografts by KONDA, SHEELA D, WANG, STEVEN, BRECHBIEL, MARTIN, WIENER, ERIK C

“…Konda SD, Wang S, Brechbiel M, et al. Biodistribution of a Gd-folate dendrimer, generation = 4, in mice with folate-receptor positive and negative ovarian…”
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Metal-Directed Self-Assembly of Ethylenediamine-Based Dendrons by Narayanan, Venkatraj V, Wiener, Erik C

“…Research was carried out to develop molecules with multiple targeting moieties for the in vivo study of tumor environment. A Co(III) meta core and…”
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Specific targeting of folate-dendrimer MRI contrast agents to the high affinity folate receptor expressed in ovarian tumor xenografts by Konda, S D, Aref, M, Wang, S, Brechbiel, M, Wiener, E C

“…The need to develop target-specific MRI contrast agents to aid in disease characterization remains highly essential. In this study, we present a generation…”
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Specific targeting of folate–dendrimer MRI contrast agents to the high affinity folate receptor expressed in ovarian tumor xenografts by Konda, S

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Syntheses and crystal structures of gadolinium and europium complexes of AAZTA analogues by Sengar, Raghvendra S., Nigam, Archana, Geib, Steven J., Wiener, Erik C.

“…The Gd and Eu complexes of a new AAZTA ligand, with a hydroxyl side chain, show nine-coordinated metal center in dimeric structure with one inner sphere water…”
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Magnetic resonance imaging–guided adoptive cellular immunotherapy of central nervous system tumors with a T 1 contrast agent by Sengar, Raghvendra S., Spokauskiene, Laima, Steed, Daniel P., Griffin, Patricia, Arbujas, Norma, Chambers, William H., Wiener, Erik C.

“…Dendritic cells (DCs) are the most effective antigen‐presenting cells (APCs) and are used in a variety of immunotherapeutic approaches. Adoptive cellular…”
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