Search Results - "WIEGMANN, K."

Cytochrome c oxidase deficiency accelerates mitochondrial apoptosis by activating ceramide synthase 6 by Schüll, S, Günther, S D, Brodesser, S, Seeger, J M, Tosetti, B, Wiegmann, K, Pongratz, C, Diaz, F, Witt, A, Andree, M, Brinkmann, K, Krönke, M, Wiesner, R J, Kashkar, H

“…Although numerous pathogenic changes within the mitochondrial respiratory chain (RC) have been associated with an elevated occurrence of apoptosis within the…”
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Power of Bioenergy-Related Standards to Protect Biodiversity by HENNENBERG, K. J., DRAGISIC, C., HAYE, S., HEWSON, J., SEMROC, B., SAVY, C., WIEGMANN, K., FEHRENBACH, H., FRITSCHE, U. R.

“…The sustainable production of bioenergy is vital to avoiding negative impacts on environmental goods such as climate, soil, water, and especially biodiversity…”
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Evidence for utility of the same PCR-based markers for selection of extreme resistance to Potato virus Y controlled by Rysto of Solanum stoloniferum derived from different sources by Valkonen, J.P.T, Wiegmann, K, Hämäläinen, J.H, Marczewski, W, Watanabe, K.N

“…The tuber-bearing wild potato species, Solanum stoloniferum, carries a dominant gene, Rysto, which confers extreme resistance (ER) to Potato virus Y (PVY)…”
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TNF-α-converting enzyme (TACE ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species by Vahdat, A M, Reiners, K S, Simhadri, V L, Eichenauer, D A, Böll, B, Chalaris, A, Simhadri, V R, Wiegmann, K, Krell, H-W, Rose-John, S, Engert, A, von Strandmann, E P, Hansen, H P

“…Combinations with proteasome inhibitors are currently being investigated to improve the therapy of hematological malignancies. We previously found that…”
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Crystal structure of the BEACH domain reveals an unusual fold and extensive association with a novel PH domain by Jogl, Gerwald, Shen, Yang, Gebauer, Damara, Li, Jiang, Wiegmann, Katja, Kashkar, Hamid, Krönke, Martin, Tong, Liang

“…The BEACH domain is highly conserved in a large family of eukaryotic proteins, and is crucial for their functions in vesicle trafficking, membrane dynamics and…”
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CD28 signals through acidic sphingomyelinase by Boucher, L M, Wiegmann, K, Fütterer, A, Pfeffer, K, Machleidt, T, Schütze, S, Mak, T W, Krönke, M

“…T cell receptor recognition of antigen can lead either to T lymphocyte differentiation and proliferation or to a state of unresponsiveness, which is dependent…”
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Sphingomyelinase activates proteolytic I kappa B-alpha degradation in a cell-free system by MACHLEIDT, T, WIEGMANN, K, HENKEL, T, SCHÜTZE, S, BAUEUERLE, P, KRÖNKE, M

“…Tumor necrosis factor (TNF) is one of the most potent physiological inducers of the nuclear transcription factor kappa B (NF-kappa B). A key event in the…”
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Tumor necrosis factor (TNF)‐alpha activates c‐raf‐1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase by Belka, C., Wiegmann, K., Adam, D., Holland, R., Neuloh, M., Herrmann, F., Krönke, M., Brach, M.A.

“…TNF‐alpha mediates proliferation, functional activation and apoptotic death of cells depending upon its concentration and target cell type. The signaling…”
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Human 55-kDa receptor for tumor necrosis factor coupled to signal transduction cascades by WIEGMANN, K, SCHÜTZE, S, KAMPEN, E, HIMMLER, A, MACHLEIDT, T, KRÖNKE, M

“…The numerous biological activities of tumor necrosis factor (TNF) appear mediated by two types of receptors of 55 kDa (TR55) and 75 kDa (TR75) molecular mass…”
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The motion of trees in the wind: a data synthesis by Jackson, Toby D, Sethi, Sarab, Dellwik, Ebba, Angelou, Nikolas, Bunce, Amanda, van Emmerik, Tim, Duperat, Marine, Ruel, Jean-Claude, Wellpott, Axel, Van Bloem, Skip, Achim, Alexis, Kane, Brian, Ciruzzi, Dominick M, Loheide II, Steven P, James, Ken, Burcham, Daniel, Moore, John, Schindler, Dirk, Kolbe, Sven, Wiegmann, Kilian, Rudnicki, Mark, Lieffers, Victor J, Selker, John, Gougherty, Andrew V, Newson, Tim, Koeser, Andrew, Miesbauer, Jason, Samelson, Roger, Wagner, Jim, Ambrose, Anthony R, Detter, Andreas, Rust, Steffen, Coomes, David, Gardiner, Barry

“…Interactions between wind and trees control energy exchanges between the atmosphere and forest canopies. This energy exchange can lead to the widespread damage…”
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Modelling sustainable bioenergy potentials from agriculture for Germany and Eastern European countries by Simon, Sonja, Wiegmann, Kirsten

“…This paper presents a model for analyzing the sustainable potential of agricultural biomass for energy production. Available land and residue potentials are…”
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Novel Tumor Necrosis Factor-responsive Mammalian Neutral Sphingomyelinase-3 Is a C-tail-anchored Protein by Krut, Oleg, Wiegmann, Katja, Kashkar, Hamid, Yazdanpanah, Benjamin, Krönke, Martin

“…Two genes encoding neutral sphingomyelinases-1 and -2 (sphingomyelin phosphodiesterases-2 and -3) have been recently identified that hydrolyze sphingomyelin to…”
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Acid Sphingomyelinase Is Indispensable for UV Light-induced Bax Conformational Change at the Mitochondrial Membrane by Kashkar, Hamid, Wiegmann, Katja, Yazdanpanah, Benjamin, Haubert, Dirk, Krönke, Martin

“…Ultraviolet light-induced apoptosis can be caused by DNA damage but also involves immediate-early cell death cascades characteristic of death receptor…”
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Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling by Wiegmann, K, Schütze, S, Machleidt, T, Witte, D, Krönke, M

“…Ceramide produced by sphingomyelinases (SMases) has been recognized as an important second messenger in growth factor receptor signaling. Tumor necrosis factor…”
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TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown by Schütze, S, Potthoff, K, Machleidt, T, Berkovic, D, Wiegmann, K, Krönke, M

“…In this paper, we describe a phospholipid transmission pathway mediating tumor necrosis factor (TNF) activation of the nuclear transcription factor kappa B…”
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FAN, a Novel WD-Repeat Protein, Couples the p55 TNF-Receptor to Neutral Sphingomyelinase by Adam-Klages, Sabine, Adam, Dieter, Wiegmann, Katja, Struve, Sandra, Kolanus, Waldemar, Schneider-Mergener, Jens, Krönke, Martin

“…The initiation of intracellular signaling events through the 55 kDa tumor necrosis factor–receptor (TNF-R55) appears to depend on protein intermediates that…”
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Superantigen-induced transcriptional activation of the human TNF gene promoter in T cells by Krämer, B, Machleidt, T, Wiegmann, K, Krönke, M

“…Superantigens, such as staphylococcal enterotoxins (SE), cause food poisoning and shock, which is mediated at least in part by TNF. We have examined the…”
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High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22 by Pfizenmaier, K, Wiegmann, K, Scheurich, P, Kronke, M, Merlin, G, Aguet, M, Knowles, BB, Ucer, U

“…We have used human-rodent somatic cell hybrids to investigate the regional localization of the IFN-gamma R gene on human chromosome 6 and studied functional…”
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Inhibition of Receptor Internalization by Monodansylcadaverine Selectively Blocks p55 Tumor Necrosis Factor Receptor Death Domain Signaling by Schütze, Stefan, Machleidt, Thomas, Adam, Dieter, Schwandner, Ralf, Wiegmann, Katja, Kruse, Marie-Luise, Heinrich, Michael, Wickel, Marc, Krönke, Martin

“…The 55-kDa receptor for tumor necrosis factor (TR55) triggers multiple signaling cascades initiated by adapter proteins like TRADD and FAN. By use of the…”
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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection by Pfeffer, K, Matsuyama, T, Kündig, T M, Wakeham, A, Kishihara, K, Shahinian, A, Wiegmann, K, Ohashi, P S, Krönke, M, Mak, T W

“…The multiple biological activities of tumor necrosis factor (TNF) are mediated by two distinct cell surface receptors of 55 kd (TNFRp55) and 75 kd (TNFRp75)…”
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