Search Results - "WIEGAND, S"
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Depression, anxiety, fatigue, and quality of life in a large sample of patients suffering from head and neck cancer in comparison with the general population
Published in BMC cancer (22-01-2021)“…Treatment of head and neck cancer (HNC) often leads to visible and severe functional impairments. In addition, patients often suffer from a variety of…”
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Efficacy of sirolimus in children with lymphatic malformations of the head and neck
Published in European archives of oto-rhino-laryngology (01-08-2022)“…Purpose Children with extensive lymphatic malformations of the head and neck often suffer from functional impairment and aesthetic deformity which…”
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Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity
Published in Nature communications (24-04-2020)“…Small molecules that selectively kill senescent cells (SCs), termed senolytics, have the potential to prevent and treat various age-related diseases and extend…”
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Evidence-Based Review of Laryngeal Cancer Surgery
Published in Laryngo- rhino- otologie (01-04-2016)“…Surgical treatment of laryngeal cancer has been established for decades. In addition to total laryngectomy, which was first performed in 1873, a large number…”
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Delta-Like Ligand 4 (Dll4) Is Induced by VEGF as a Negative Regulator of Angiogenic Sprouting
Published in Proceedings of the National Academy of Sciences - PNAS (27-02-2007)“…Genetic deletion studies have shown that haploinsufficiency of Delta-like ligand (Dll) 4, a transmembrane ligand for the Notch family of receptors, results in…”
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Hepatitis B core-related antigen (HBcrAg) levels in the natural history of hepatitis B virus infection in a large European cohort predominantly infected with genotypes A and D
Published in Clinical microbiology and infection (01-06-2015)“…Hepatitis B core-related antigen (HBcrAg) has been suggested as an additional marker of hepatitis B virus (HBV) infection. HBcrAg combines the antigenic…”
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Therapy of tumor recurrences or secondary carcinomas in pretreated area is not compatible with the primary therapy in non-previously treated tissue - an overview
Published in Laryngo- rhino- otologie (01-12-2023)“…There are different initial situations in the treatment of local or locoregional recurrences, secondary carcinomas or residual squamous cell carcinomas of the…”
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Screening for distress, related problems and perceived need for psycho-oncological support in head and neck squamous cell carcinoma (HNSCC) patients: a retrospective cohort study
Published in BMC cancer (30-04-2021)“…In different cancer entities, several studies have shown the adverse effects of cancer on mental health, psychological well-being and the increased risk of…”
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DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas
Published in Journal of hematology and oncology (16-07-2020)“…Patients with advanced T cell lymphomas (TCLs) have limited therapeutic options and poor outcomes in part because their TCLs evade apoptosis through…”
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Systemic inflammatory response after endoscopic surgery of Zenker's diverticulum
Published in Acta otorhino-laryngologica italica (01-08-2019)“…Zenker’s diverticulum can be treated with a carbon dioxide laser or linear stapling device. A retrospective study on patients undergoing elective surgery for…”
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Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF
Published in Science (American Association for the Advancement of Science) (18-06-1999)“…In contrast with the prevailing view that most tumors and metastases begin as avascular masses, evidence is presented here that a subset of tumors instead…”
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Planctopirus ephydatiae, a novel Planctomycete isolated from a freshwater sponge
Published in Systematic and applied microbiology (01-01-2020)“…The microbiome of freshwater sponges is rarely studied, and not a single novel bacterial species has been isolated and subsequently characterized from a…”
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Thermodiffusion of Charged Colloids: Single-Particle Diffusion
Published in Langmuir (13-02-2007)“…An expression for the single-particle thermal diffusion coefficient of a charged colloidal sphere is derived on the basis of force balance on the Brownian time…”
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New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
Published in Oncogene (20-09-1999)“…Our analyses in several different tumor settings challenge the prevailing view that malignancies and metastases generally initiate as avascular masses that…”
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Induction chemotherapy (IC) followed by radiotherapy (RT) versus cetuximab plus IC and RT in advanced laryngeal/hypopharyngeal cancer resectable only by total laryngectomy—final results of the larynx organ preservation trial DeLOS-II
Published in Annals of oncology (01-10-2018)“…The German multicenter randomized phase II larynx organ preservation (LOP) trial DeLOS-II was carried out to prove the hypothesis that cetuximab (E) added to…”
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EP17.17: Plasma sFlt‐1/PlGF ratio as multiples of the median predicts pre‐eclampsia with severe features within two weeks
Published in Ultrasound in obstetrics & gynecology (01-09-2024)Get full text
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Propranolol therapy for infantile haemangiomas: Review of the literature
Published in International journal of pediatric otorhinolaryngology (01-04-2010)“…Abstract Objectives Haemangiomas are the most common tumors of infancy affecting approximately 1 in 10 children. Unlike other tumors, haemangiomas enter an…”
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Organ preservation in advanced laryngeal/hypopharyngeal carcinoma: lessons from the DeLOS-II trial
Published in HNO (01-09-2020)“…Patients with locoregionally advanced laryngeal and hypopharyngeal squamous cell carcinomas (LHSCC) comprise two broad groups: those who are candidates for…”
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Prevalence of prediabetes and type 2 diabetes in children with obesity and increased transaminases in European German‐speaking countries. Analysis of the APV initiative
Published in Pediatric obesity (01-04-2020)“…Summary Background Non‐alcoholic fatty liver disease (NAFLD), prediabetes and type 2 diabetes mellitus are known to be closely linked with obesity as early as…”
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Health related quality of life associated with extreme obesity in adolescents - results from the baseline evaluation of the YES-study
Published in Health and quality of life outcomes (05-03-2020)“…Obesity can significantly reduce health-related quality of life (HRQoL) and may lead to numerous health problems even in youths. This study aimed to…”
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