Search Results - "WIEDENMANN, Bertram"

Neuroendocrine neoplasia of the gastrointestinal tract revisited: towards precision medicine by Rindi, Guido, Wiedenmann, Bertram

“…Over the past 5 years, a number of notable research advances have been made in the field of neuroendocrine cancer, specifically with regard to neuroendocrine…”
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Somatostatin Analogues in the Treatment of Neuroendocrine Tumors: Past, Present and Future by Stueven, Anna Kathrin, Kayser, Antonin, Wetz, Christoph, Amthauer, Holger, Wree, Alexander, Tacke, Frank, Wiedenmann, Bertram, Roderburg, Christoph, Jann, Henning

“…In recent decades, the incidence of neuroendocrine tumors (NETs) has steadily increased. Due to the slow-growing nature of these tumors and the lack of early…”
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Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis by Sigal, Michael, Logan, Catriona Y., Kapalczynska, Marta, Mollenkopf, Hans-Joachim, Berger, Hilmar, Wiedenmann, Bertram, Nusse, Roeland, Amieva, Manuel R., Meyer, Thomas F.

“…Myofibroblast-derived R-spondin 3 orchestrates regeneration of antral stomach epithelium via Wnt signalling in Axin2 + stem cells. Sustaining stomach tissue…”
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Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan by Ito, Tetsuhide, Sasano, Hironobu, Tanaka, Masao, Osamura, R. Yoshiyuki, Sasaki, Iwao, Kimura, Wataru, Takano, Koji, Obara, Takao, Ishibashi, Miyuki, Nakao, Kazuwa, Doi, Ryuichiro, Shimatsu, Akira, Nishida, Toshirou, Komoto, Izumi, Hirata, Yukio, Nakamura, Kazuhiko, Igarashi, Hisato, Jensen, Robert T, Wiedenmann, Bertram, Imamura, Masayuki

“…Background There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan. Methods We examined the…”
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Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors by Raymond, Eric, Dahan, Laetitia, Raoul, Jean-Luc, Bang, Yung-Jue, Borbath, Ivan, Lombard-Bohas, Catherine, Valle, Juan, Metrakos, Peter, Smith, Denis, Vinik, Aaron, Chen, Jen-Shi, Hörsch, Dieter, Hammel, Pascal, Wiedenmann, Bertram, Van Cutsem, Eric, Patyna, Shem, Lu, Dongrui Ray, Blanckmeister, Carolyn, Chao, Richard, Ruszniewski, Philippe

“…In this trial, daily oral sunitinib was associated with a median progression-free survival of 11.4 months, as compared with 5.5 months for placebo (hazard…”
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Reply to ‘Time for a change and to adopt a novel molecular genomic approach in NETs’ by Rindi, Guido, Wiedenmann, Bertram

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The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific by Benckert, Julia, Schmolka, Nina, Kreschel, Cornelia, Zoller, Markus Josef, Sturm, Andreas, Wiedenmann, Bertram, Wardemann, Hedda

“…Mucosal antibody responses play a major role in mediating homeostasis with the intestinal flora. It has been suggested that imbalance in the IgA+ and IgG+…”
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Improving compliance to colorectal cancer screening using blood and stool based tests in patients refusing screening colonoscopy in Germany by Adler, Andreas, Geiger, Sebastian, Keil, Anne, Bias, Harald, Schatz, Philipp, deVos, Theo, Dhein, Jens, Zimmermann, Mathias, Tauber, Rudolf, Wiedenmann, Bertram

“…Despite strong recommendations for colorectal cancer (CRC) screening, participation rates are low. Understanding factors that affect screening choices is…”
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Surgery with Radical Intent: Is There an Indication for G3 Neuroendocrine Neoplasms? by Merola, Elettra, Rinke, Anja, Partelli, Stefano, Gress, Thomas M., Andreasi, Valentina, Kollár, Attila, Perren, Aurel, Christ, Emanuel, Panzuto, Francesco, Pascher, Andreas, Jann, Henning, Arsenic, Ruza, Cremer, Birgit, Kaemmerer, Daniel, Kump, Patrizia, Lipp, Rainer W., Agaimy, Abbas, Wiedenmann, Bertram, Falconi, Massimo, Pavel, Marianne E.

“…Background While platinum-based chemotherapy represents the standard treatment for advanced grade 3 (G3) neuroendocrine neoplasms (NENs) according to the…”
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R-spondin-3 induces secretory, antimicrobial Lgr5+ cells in the stomach by Sigal, Michael, Reinés, Maria del Mar, Müllerke, Stefanie, Fischer, Cornelius, Kapalczynska, Marta, Berger, Hilmar, Bakker, Elvira R. M., Mollenkopf, Hans-Joachim, Rothenberg, Michael E., Wiedenmann, Bertram, Sauer, Sascha, Meyer, Thomas F.

“…Wnt signalling stimulated by binding of R-spondin (Rspo) to Lgr-family members is crucial for gastrointestinal stem cell renewal. Infection of the stomach with…”
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Neuroendocrine tumors of midgut and hindgut origin: Tumor‐node‐metastasis classification determines clinical outcome by Jann, Henning, Roll, Stephanie, Couvelard, Anne, Hentic, Olivia, Pavel, Marianne, Müller‐Nordhorn, Jacqueline, Koch, Martin, Röcken, Christoph, Rindi, Guido, Ruszniewski, Philippe, Wiedenmann, Bertram, Pape, Ulrich‐Frank

“…BACKGROUND: Prognostic classification of neuroendocrine tumor (NET) patients is difficult due to the complexity of current classification systems. A recent…”
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PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study by Branchi, Federica, Klingenberg-Noftz, Rolf, Friedrich, Kristina, Bürgel, Nataly, Daum, Severin, Buchkremer, Juliane, Sonnenberg, Elena, Schumann, Michael, Treese, Christoph, Tröger, Hanno, Lissner, Donata, Epple, Hans-Jörg, Siegmund, Britta, Stroux, Andrea, Adler, Andreas, Veltzke-Schlieker, Winfried, Autenrieth, Daniel, Leonhardt, Silke, Fischer, Andreas, Jürgensen, Christian, Pape, Ulrich-Frank, Wiedenmann, Bertram, Möschler, Oliver, Schreiner, Maximilian, Strowski, Mathias Z., Hempel, Volkmar, Huber, Yvonne, Neumann, Helmut, Bojarski, Christian

“…Background A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding…”
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Daily Oral Everolimus Activity in Patients With Metastatic Pancreatic Neuroendocrine Tumors After Failure of Cytotoxic Chemotherapy: A Phase II Trial by Yao, James C, Lombard-Bohas, Catherine, Baudin, Eric, Kvols, Larry K, Rougier, Philippe, Ruszniewski, Philippe, Hoosen, Sakina, St Peter, Jessica, Haas, Tomas, Lebwohl, David, Van Cutsem, Eric, Kulke, Matthew H, Hobday, Timothy J, O'Dorisio, Thomas M, Shah, Manisha H, Cadiot, Guillaume, Luppi, Gabriele, Posey, James A, Wiedenmann, Bertram

“…PURPOSE No established treatment exists for pancreatic neuroendocrine tumor (NET) progression after failure of chemotherapy. Everolimus (RAD001), an oral…”
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Prognostic relevance of a novel TNM classification system for upper gastroenteropancreatic neuroendocrine tumors by Pape, Ulrich‐Frank, Jann, Henning, Müller‐Nordhorn, Jacqueline, Bockelbrink, Angelina, Berndt, Uta, Willich, Stefan N., Koch, Martin, Röcken, Christoph, Rindi, Guido, Wiedenmann, Bertram

“…BACKGROUND. Neuroendocrine tumors (NETs) of the gastroenteropancreatic (GEP) system comprise a rare but challenging group of malignant neoplasms and occur at…”
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Octreotide Does Not Inhibit Proliferation in Five Neuroendocrine Tumor Cell Lines by Exner, Samantha, Prasad, Vikas, Wiedenmann, Bertram, Grötzinger, Carsten

“…Somatostatin analogs (SSA) are well-established antisecretory drugs in functionally active neuroendocrine tumors (NET). Two placebo-controlled trials have…”
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Axon Guidance Factor SLIT2 Inhibits Neural Invasion and Metastasis in Pancreatic Cancer by GÖHRIG, Andreas, DETJEN, Katharina M, FISCHER, Christian, HILFENHAUS, Georg, KÖRNER, Jan L, WELZEL, Martina, ARSENIC, Ruza, SCHMUCK, Rosa, BAHRA, Marcus, WU, Jane Y, WIEDENMANN, Bertram

“…Pancreatic ductal adenocarcinoma (PDAC) metastasizes by neural, vascular, and local invasion routes, which limit patient survival. In nerves and vessels, SLIT2…”
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Glucocorticoids regulate barrier function and claudin expression in intestinal epithelial cells via MKP-1 by Fischer, Andreas, Gluth, Markus, Weege, Friderike, Pape, Ulrich-Frank, Wiedenmann, Bertram, Baumgart, Daniel C, Theuring, Franz

“…Barrier dysfunction is pivotal to the pathogenesis of inflammatory bowel diseases (IBD) and collagenous colitis. Glucocorticoids restore barrier function in…”
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Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis by Kumar, Naveen, Prakash, Pon Ganish, Wentland, Christian, Kurian, Shilpa Mary, Jethva, Gaurav, Brinkmann, Volker, Mollenkopf, Hans-Joachim, Krammer, Tobias, Toussaint, Christophe, Saliba, Antoine-Emmanuel, Biebl, Matthias, Jürgensen, Christian, Wiedenmann, Bertram, Meyer, Thomas F., Gurumurthy, Rajendra Kumar, Chumduri, Cindrilla

“…The gastroesophageal squamocolumnar junction (GE-SCJ) is a critical tissue interface between the esophagus and stomach, with significant relevance in the…”
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Prognostic factors of long-term outcome in gastroenteropancreatic neuroendocrine tumours by Pape, Ulrich-Frank, Berndt, Uta, Müller-Nordhorn, Jacqueline, Böhmig, Michael, Roll, Stephanie, Koch, Martin, Willich, Stefan N, Wiedenmann, Bertram

“…Neuroendocrine tumours (NET) of the gastroenteropancreatic system comprise a malignant entity with a low incidence. Only limited information is available on…”
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Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting by Bolduan, Felix, Wetzel, Alexandra, Giesecke, Yvonne, Eichhorn, Ines, Alenina, Natalia, Bader, Michael, Willnow, Thomas E, Wiedenmann, Bertram, Sigal, Michael

“…A subset of neuroendocrine tumors (NETs) can cause an excessive secretion of hormones, neuropeptides, and biogenic amines into the bloodstream. These so-called…”
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