Search Results - "WICKLEY, Peter J"

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    Propofol-induced activation of protein kinase C isoforms in adult rat ventricular myocytes by WICKLEY, Peter J, XUEQIN DING, MURRAY, Paul A, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-05-2006)
    “…Myocardial protection by anesthetics is known to involve activation of protein kinase C (PKC). The authors' objective was to identify the PKC isoforms…”
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    Journal Article
  3. 3

    Propofol modulates Na+-Ca2+ exchange activity via activation of protein kinase C in diabetic cardiomyocytes by WICKLEY, Peter J, SHIGA, Toshiya, MURRAY, Paul A, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-02-2007)
    “…The authors' objective was to identify the role of the Na+-Ca2+ exchanger (NCX) in mediating the contractile dysfunction observed in diabetic cardiomyocytes…”
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    Journal Article
  4. 4

    Propofol Activates and Allosterically Modulates Recombinant Protein Kinase Cε by WICKLEY, Peter J, YUGE, Ryo, MARTIN, Brad A, MEYER, Jacob S, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-07-2009)
    “…Myocardial protection by anesthetics is known to involve activation of protein kinase C epsilon (PKC epsilon). A key step in the activation process is…”
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    Journal Article
  5. 5

    Experimental conditions are important determinants of cardiac inotropic effects of propofol by KANAYA, Noriaki, GABLE, Brad, WICKLEY, Peter J, MURRAY, Paul A, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-11-2005)
    “…The rationale for this study is that the depressant effect of propofol on cardiac function in vitro is highly variable but may be explained by differences in…”
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    Journal Article
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    Propofol restores transient receptor potential vanilloid receptor subtype-1 sensitivity via activation of transient receptor potential ankyrin receptor subtype-1 in sensory neurons by Zhang, Hongyu, Wickley, Peter J, Sinha, Sayantani, Bratz, Ian N, Damron, Derek S

    Published in Anesthesiology (Philadelphia) (01-05-2011)
    “…Cross talk between peripheral nociceptors belonging to the transient receptor potential vanilloid receptor subtype-1 (TRPV1) and ankyrin subtype-1 (TRPA1)…”
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    Journal Article
  7. 7

    Propofol Modulates Agonist-induced Transient Receptor Potential Vanilloid Subtype-1 Receptor Desensitization via a Protein Kinase Cε-dependent Pathway in Mouse Dorsal Root Ganglion Sensory Neurons by WICKLEY, Peter J, YUGE, Ryo, RUSSELL, Mary S, HONGYU ZHANG, SULAK, Michael A, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-10-2010)
    “…Background The activity of transient receptor potential vanilloid subtype-1 (TRPV1) receptors, key nociceptive transducers in dorsal root ganglion sensory…”
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    Journal Article
  8. 8

    Propofol decreases myofilament Ca2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes by WICKLEY, Peter J, SHIGA, Toshiya, MURRAY, Paul A, DAMRON, Derek S

    Published in Anesthesiology (Philadelphia) (01-05-2006)
    “…The authors' objective was to assess the role of protein kinase C (PKC) and nitric oxide synthase (NOS) in mediating the effects of propofol on diabetic…”
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    Journal Article
  9. 9

    Beta 1-adrenergic receptor autoantibodies mediate dilated cardiomyopathy by agonistically inducing cardiomyocyte apoptosis by Jane-wit, Daniel, Altuntas, Cengiz Z, Johnson, Justin M, Yong, Sandro, Wickley, Peter J, Clark, Pamela, Wang, Qing, Popović, Zoran B, Penn, Marc S, Damron, Derek S, Perez, Dianne M, Tuohy, Vincent K

    Published in Circulation (New York, N.Y.) (24-07-2007)
    “…Antibodies to the beta1-adrenergic receptor (beta1AR) are detected in a substantial number of patients with idiopathic dilated cardiomyopathy (DCM). The…”
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    Journal Article
  10. 10

    Propofol modulates agonist-induced transient receptor potential vanilloid subtype-1 receptor desensitization via a protein kinase Cepsilon-dependent pathway in mouse dorsal root ganglion sensory neurons by Wickley, Peter J, Yuge, Ryo, Russell, Mary S, Zhang, Hongyu, Sulak, Michael A, Damron, Derek S

    Published in Anesthesiology (Philadelphia) (01-10-2010)
    “…The activity of transient receptor potential vanilloid subtype-1 (TRPV1) receptors, key nociceptive transducers in dorsal root ganglion sensory neurons, is…”
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    Journal Article
  11. 11

    {szligbeta} sub(1)-Adrenergic Receptor Autoantibodies Mediate Dilated Cardiomyopathy by Agonistically Inducing Cardiomyocyte Apoptosis by Jane-wit, Daniel, Altuntas, Cengiz Z, Johnson, Justin M, Yong, Sandro, Wickley, Peter J, Clark, Pamela, Wang, Qing, Popovic, Zoran B, Penn, Marc S, Damron, Derek S, Perez, Dianne M, Tuohy, Vincent K

    Published in Circulation (New York, N.Y.) (01-07-2007)
    “…BACKGROUND: Antibodies to the {szligbeta} sub(1)-adrenergic receptor ({szligbeta} sub(1)AR) are detected in a substantial number of patients with idiopathic…”
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    Journal Article
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    Propofol-Anesthesia, Diabetes and Myocardial Signal Transduction: Role of Protein Kinase C and Nitric Oxide by Wickley, Peter J

    Published 01-01-2008
    “…Induction and maintenance of anesthesia typically causes myocardial depression in healthy patients presenting for cardiac surgery. Moreover, the diabetic…”
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    Dissertation
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