Search Results - "WHITE, Tommi A"
-
1
DRPnet: automated particle picking in cryo-electron micrographs using deep regression
Published in BMC bioinformatics (08-02-2021)“…Identification and selection of protein particles in cryo-electron micrographs is an important step in single particle analysis. In this study, we developed a…”
Get full text
Journal Article -
2
Cross-Species Permissivity: Structure of a Goat Adeno-Associated Virus and Its Complex with the Human Receptor AAVR
Published in Journal of virology (21-12-2022)“…Adeno-associated virus (AAV) is a small ssDNA satellite virus of high interest (in recombinant form) as a safe and effective gene therapy vector. AAV's human…”
Get full text
Journal Article -
3
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure
Published in PLoS pathogens (01-12-2010)“…The initial step in target cell infection by human, and the closely related simian immunodeficiency viruses (HIV and SIV, respectively) occurs with the binding…”
Get full text
Journal Article -
4
The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells
Published in eLife (29-09-2022)“…causes severe invasive candidiasis. infection requires the virulence factor candidalysin (CL) which damages target cell membranes. However, the mechanism that…”
Get full text
Journal Article -
5
The Structure of an AAV5-AAVR Complex at 2.5 Å Resolution: Implications for Cellular Entry and Immune Neutralization of AAV Gene Therapy Vectors
Published in Viruses (18-11-2020)“…Adeno-Associated Virus is the leading vector for gene therapy. Although it is the vector for all in vivo gene therapies approved for clinical use by the US…”
Get full text
Journal Article -
6
Ultrastructural Analysis of Chikungunya Virus Dissemination from the Midgut of the Yellow Fever Mosquito, Aedes aegypti
Published in Viruses (18-10-2018)“…The transmission cycle of chikungunya virus (CHIKV) requires that mosquito vectors get persistently infected with the virus, following its oral acqsuisition…”
Get full text
Journal Article -
7
Rigid crosslinking of the CD3 complex leads to superior T cell stimulation
Published in Frontiers in immunology (30-08-2024)“…Functionally bivalent non-covalent Fab dimers (Bi-Fabs) specific for the TCR/CD3 complex promote CD3 signaling on T cells. While comparing functional responses…”
Get full text
Journal Article -
8
Spatial Restrictions in Chemotaxis Signaling Arrays: A Role for Chemoreceptor Flexible Hinges across Bacterial Diversity
Published in International journal of molecular sciences (19-06-2019)“…The chemotactic sensory system enables motile bacteria to move toward favorable environments. Throughout bacterial diversity, the chemoreceptors that mediate…”
Get full text
Journal Article -
9
Cryo-ePDF: Overcoming Electron Beam Damage to Study the Local Atomic Structure of Amorphous ALD Aluminum Oxide Thin Films within a TEM
Published in ACS omega (06-04-2021)“…Atomic layer deposition (ALD) provides uniform and conformal thin films that are of interest for a range of applications. To better understand the properties…”
Get full text
Journal Article -
10
Nano-layer deposition of metal oxides via a condensed water film
Published in Communications materials (02-03-2020)“…Nanocoatings on solids can be achieved by various processes, including sol-gel and atomic layer deposition. However, challenges remain for achieving uniform…”
Get full text
Journal Article -
11
Structure and Kinetics of Monofunctional Proline Dehydrogenase from Thermus thermophilus
Published in The Journal of biological chemistry (11-05-2007)“…Proline dehydrogenase (PRODH) and Δ1-pyrroline-5-carboxylate dehydrogenase (P5CDH) catalyze the two-step oxidation of proline to glutamate. They are distinct…”
Get full text
Journal Article -
12
Significantly Enhanced Emission Stability of CsPbBr3 Nanocrystals via Chemically Induced Fusion Growth for Optoelectronic Devices
Published in ACS applied nano materials (26-11-2018)“…Lead–halide perovskite nanocrystals (PNCs) have attracted much attention in recent years due to their outstanding optical properties. We report here a new…”
Get full text
Journal Article -
13
Three-Dimensional Structures of Soluble CD4-Bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-Electron Tomography
Published in Journal of Virology (01-12-2011)“…OA Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+…”
Get full text
Journal Article -
14
Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2010)“…The bifunctional proline catabolic flavoenzyme, proline utilization A (PutA), catalyzes the oxidation of proline to glutamate via the sequential activities of…”
Get full text
Journal Article -
15
Li4Ti5O12 coated with ultrathin aluminum-doped zinc oxide films as an anode material for lithium-ion batteries
Published in Journal of power sources (01-10-2019)“…Aluminum-doped zinc oxide (AZO) films were coated on the surface of Li4Ti5O12 (LTO) particles via atomic layer deposition (ALD) in a fluidized bed reactor. The…”
Get full text
Journal Article -
16
Highly active and selective Cu-ZnO based catalyst for methanol and dimethyl ether synthesis via CO2 hydrogenation
Published in Fuel (Guildford) (01-03-2019)“…•Prepared Cu-ZnO based catalyst has a high BET surface area (SA) and Cu SA.•Precursor concentration greatly affected structural properties of catalyst.•26.1%…”
Get full text
Journal Article -
17
Asymmetric Cryo-EM Structure of Anthrax Toxin Protective Antigen Pore with Lethal Factor N-Terminal Domain
Published in Toxins (22-09-2017)“…The anthrax lethal toxin consists of protective antigen (PA) and lethal factor (LF). Understanding both the PA pore formation and LF translocation through the…”
Get full text
Journal Article -
18
Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging
Published in Journal of structural biology (01-05-2012)“…We have previously used cryo-electron tomography combined with sub-volume averaging and classification to obtain 3D structures of macromolecular assemblies in…”
Get full text
Journal Article -
19
Inhibition of regrowth of planktonic and biofilm bacteria after peracetic acid disinfection
Published in Water research (Oxford) (01-02-2019)“…Peracetic acid (PAA) is a promising alternative to chlorine for disinfection; however, bacterial regrowth after PAA disinfection is poorly understood. This…”
Get full text
Journal Article -
20
The Chaperonin GroEL: A Versatile Tool for Applied Biotechnology Platforms
Published in Frontiers in molecular biosciences (15-05-2018)“…The nucleotide-free chaperonin GroEL is capable of capturing transient unfolded or partially unfolded states that flicker in and out of existence due to…”
Get full text
Journal Article