Search Results - "WHITE, Sylvia S"

Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease by McMillan, Pamela J, White, Sylvia S, Franklin, Allyn, Greenup, J. Lynne, Leverenz, James B, Raskind, Murray A, Szot, Patricia

“…Abstract In Parkinson's disease (PD), there is a significant loss of noradrenergic neurons in the locus coeruleus (LC) in addition to the loss of dopaminergic…”
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Norepinephrine-Deficient Mice Have Increased Susceptibility to Seizure-Inducing Stimuli by Szot, Patricia, Weinshenker, David, White, Sylvia S, Robbins, Carol A, Rust, Nicole C, Schwartzkroin, Philip A, Palmiter, Richard D

“…Several lines of evidence suggest that norepinephrine (NE) can modulate seizure activity. However, the experimental methods used in the past cannot exclude the…”
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Compensatory Changes in the Noradrenergic Nervous System in the Locus Ceruleus and Hippocampus of Postmortem Subjects with Alzheimer's Disease and Dementia with Lewy Bodies by Szot, Patricia, White, Sylvia S, Greenup, J. Lynne, Leverenz, James B, Peskind, Elaine R, Raskind, Murray A

“…In Alzheimer's disease (AD), there is a significant loss of locus ceruleus (LC) noradrenergic neurons. However, functional and anatomical evidence indicates…”
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Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice by Szot, Patricia, Van Dam, Debby, White, Sylvia S., Franklin, Allyn, Staufenbiel, Matthias, De Deyn, Peter Paul

“…Alzheimer's disease (AD), a neurodegenerative disorder, is characterized by the loss of neurons in specific regions of the CNS including the locus coeruleus…”
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Stress-induced activity in the locus coeruleus is not sensitive to stressor controllability by McDevitt, Ross A, Szot, Patricia, Baratta, Michael V, Bland, Sondra T, White, Sylvia S, Maier, Steven F, Neumaier, John F

“…Abstract An important factor in determining the adverse consequences of a stress experience is the degree to which an individual can exert control over the…”
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Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo by Weinshenker, David, White, Sylvia S, Javors, Martin A, Palmiter, Richard D, Szot, Patricia

“…The norepinephrine transporter (NET) regulates adrenoreceptor signaling by controlling the availability of synaptic norepinephrine (NE), and it is a direct…”
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The ketogenic diet does not alter brain expression of orexigenic neuropeptides by Tabb, Kroshona, Szot, Patricia, White, Sylvia S., Liles, L. Cameron, Weinshenker, David

“…Neuropeptide Y (NPY) and galanin are neuropeptides that are regulated by energy states and are also anticonvulsant. We tested the hypothesis that the…”
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Cloning, analysis, and bacterial expression of human farnesyl pyrophosphate synthetase and its regulation in Hep G2 cells by Sheares, Bradley T, White, Sylvia S, Molowa, David T, Chan, Karen, Ding, Victor D. H, Kroon, Paulus A, Bostedor, Richard G, Karkas, John D

“…A partial length cDNA encoding farnesyl pyrophosphate synthetase (hpt807) has been isolated from a human fetal liver cDNA library in lambda gt11. DNA sequence…”
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Genetic Comparison of Seizure Control by Norepinephrine and Neuropeptide Y by Weinshenker, David, Szot, Patricia, Miller, Nicole S, Rust, Nicole C, Hohmann, John G, Pyati, Ujwal, White, Sylvia S, Palmiter, Richard D

“…Epilepsy is a disease of neuronal hyperexcitability, and pharmacological and genetic studies have identified norepinephrine (NE) and neuropeptide Y (NPY) as…”
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Tyrosine hydroxylase mRNA is increased in old age and norepinephrine uptake transporter mRNA is decreased in middle age in locus coeruleus of Brown–Norway rats by Shores, Molly M, White, Sylvia S, Veith, Richard C, Patricia Szot

“…In normal aging, cell loss occurs in the locus coeruleus (LC), the major noradrenergic nucleus in the brain. This study examined changes in the LC of aged rats…”
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α1-Adrenoreceptor in human hippocampus : Binding and receptor subtype mRNA expression by SZOT, Patricia, WHITE, Sylvia S, GREENUP, J. Lynne, LEVERENZ, James B, PESKIND, Elaine R, RASKIND, Murray A

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Behavioral and metabolic features of repetitive seizures in immature and mature rats by Szot, Patricia, White, Sylvia S, McCarthy, Elizabeth B, Turella, Andrew, Rejniak, Starr X, Schwartzkroin, Philip A

“…Seizure incidence varies significantly with age, with seizure susceptibility particularly high during the first few years of life. Of significant concern is…”
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Valproic acid, but not lamotrigine, suppresses seizure-induced c- fos and c- Jun mRNA expression by Szot, Patricia, White, Sylvia S., Shen, Danny D., Anderson, Gail D.

“…Seizure-induced activity has been shown to increase the expression of immediate early genes (IEGs) c- fos and c- Jun in the CNS. Anti-epileptic drugs (AEDs)…”
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Age-dependent differences in flurothyl-induced c-fos and c-jun mRNA expression in the mouse brain by Storey, Thomas W, Rho, Jong M, White, Sylvia S, Sankar, Raman, Szot, Patricia

“…Numerous studies have examined the brain regional distribution of the immediate early gene (IEG), c-fos, following seizures induced by a variety of chemical or…”
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A comprehensive analysis of the effect of DSP4 on the locus coeruleus noradrenergic system in the rat by Szot, P, Miguelez, C, White, S.S, Franklin, A, Sikkema, C, Wilkinson, C.W, Ugedo, L, Raskind, M.A

“…Abstract Degeneration of the noradrenergic neurons in the locus coeruleus (LC) is a major component of Alzheimer's (AD) and Parkinson's disease (PD), but the…”
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Effect of pentylenetetrazol on the expression of tyrosine hydroxylase mRNA and norepinephrine and dopamine transporter mRNA by Szot, Patricia, White, Sylvia S, Veith, Richard C

“…Seizure activity has been shown to have differential effects on the terminal content of the monoamines, norepinephrine (NE) and dopamine (DA). Induction of…”
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Changes in adrenoreceptors in the prefrontal cortex of subjects with dementia: Evidence of compensatory changes by Szot, P, White, S.S, Greenup, J.L, Leverenz, J.B, Peskind, E.R, Raskind, M.A

“…Abstract In Alzheimer’s disease (AD) there is a significant loss of locus coeruleus (LC) noradrenergic neurons. However, recent work has shown the surviving…”
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Alterations in mRNA expression of systems that regulate neurotransmitter synaptic content in seizure-naive genetically epilepsy-prone rat (GEPR): transporter proteins and rate-limiting synthesizing enzymes for norepinephrine, dopamine and serotonin by Szot, Patricia, Reigel, Charles E, White, Sylvia S, Veith, Richard C

“…Two models of genetically epilepsy-prone rat (GEPR) exist, the GEPR-3 and GEPR-9. GEPR-3 and GEPR-9 share a deficiency in presynaptic norepinephrine (NE) and…”
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P3-298 Increased 3H-prazosin binding sites in the dentate gyrus of Alzheimer's disease and dementia with lewy bodies is due to α1 A-adrenoreceptors by Szot, Patricia, White, Sylvia S., Leverenz, James B., Greenup, Lynne, Peskind, Elaine R., Raskind, Murray A.

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P3-347: Brain derived neurotrophic factor (BDNF) mRNA expression is reduced in postmortem hippocampal dentate gyrus in Alzheimer’s disease and dementia with lewy bodies by Raskind, Murray A., Leverenz, James B., Peskind, Elaine R., White, Sylvia S., Greenup, J. Lynne, Szot, Patricia

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