Search Results - "WHITE, Kimber L"

Influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to chemotherapy in breast tumor cells by Di, Xu, Gennings, Chris, Bear, Harry D, Graham, Laura J, Sheth, Christopher M, White, Kimber L. Jr, Gewirtz, David A

“…Studies were performed to determine the influence of the phosphodiesterase-5 inhibitor, sildenafil, on sensitivity to Adriamycin (doxorubicin) in four human…”
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Novel insights on the effect of nicotine in a murine colitis model by AlSharari, Shakir D, Akbarali, Hamid I, Abdullah, Rehab A, Shahab, Omer, Auttachoat, Wimolnut, Ferreira, Gabriela A, White, Kimber L, Lichtman, Aron H, Cabral, Guy A, Damaj, M Imad

“…Studies showed that nicotine has a positive influence on symptoms of ulcerative colitis. In the present study, we explored the effect of nicotine treatment…”
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Immunomodulatory effects of black cohosh (Actaea racemosa) extract in female B6C3F1/N mice by Smith, Matthew J., Germolec, Dori R., Frawley, Rachel P., White, Kimber L.

“…Black cohosh extracts (BCE; Actaea racemosa) are being used worldwide as an alternative to hormone replacement therapy for the management of menstrual and…”
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Contact sensitizing potential of annatto extract and its two primary color components, cis-bixin and norbixin, in female BALB/c mice by Auttachoat, Wimolnut, Germolec, Dori R., Smith, Matthew J., White, Kimber L., Guo, Tai L.

“…► Annatto extract has contact allergenic effects in female BALB/c mice. ► Norbixin is not a contact sensitizer. ► cis-Bixin is likely a contact sensitizer. The…”
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Immunotoxicity studies of trans-resveratrol in male B6C3F1/N mice by Huang, Madelyn C., White, Kimber L., Elmore, Susan A., Guo, Tai L., Germolec, Dori

“…Resveratrol is a naturally occurring polyphenol that is being investigated to treat and prevent various diseases, both experimentally and in the clinic…”
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Approaches and considerations for the assessment of immunotoxicity for environmental chemicals: A workshop summary by Boverhof, Darrell R., Ladics, Greg, Luebke, Bob, Botham, Jane, Corsini, Emanuela, Evans, Ellen, Germolec, Dori, Holsapple, Michael, Loveless, Scott E, Lu, Haitian, van der Laan, Jan Willem, White, Kimber L., Yang, Yung

“…As experience is gained with toxicology testing and as new assays and technologies are developed, it is critical for stakeholders to discuss opportunities to…”
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Respiratory toxicity and immunotoxicity evaluations of microparticle and nanoparticle C60 fullerene aggregates in mice and rats following nose-only inhalation for 13 weeks by Sayers, Brian C., Germolec, Dori R., Walker, Nigel J., Shipkowski, Kelly A., Stout, Matthew D., Cesta, Mark F., Roycroft, Joseph H., White, Kimber L., Baker, Gregory L., Dill, Jeffrey A., Smith, Matthew J.

“…C60 fullerene (C60), or buckminsterfullerene, is a spherical arrangement of 60 carbon atoms, having a diameter of approximately 1 nm, and is produced naturally…”
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In vitro evaluations of innate and acquired immune responses to electrospun polydioxanone–elastin blends by Smith, Matthew J, White, Kimber L, Smith, Donna C, Bowlin, Gary L

“…Abstract Immune response testing of biomaterials is an essential component of biocompatibility assessment, particularly when the materials of interest are used…”
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Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles by Auttachoat, Wimolnut, McLoughlin, Colleen E, White, Jr, Kimber L, Smith, Matthew J

“…Nanoparticle titanium dioxide (nano-TiO2) is a white pigment widely used in foods, sunscreens, and other cosmetic products. However, it remains unclear whether…”
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Health assessment of gasoline and fuel oxygenate vapors: Immunotoxicity evaluation by White, Kimber L., Peachee, Vanessa L., Armstrong, Sarah R., Twerdok, Lorraine E., Clark, Charles R., Schreiner, Ceinwen A.

“…Female Sprague Dawley rats were exposed via inhalation to vapor condensates of either gasoline or gasoline combined with various fuel oxygenates to assess…”
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Assessment of immunotoxicity in female Fischer 344/N and Sprague Dawley rats and female B6C3F1 mice exposed to hexavalent chromium via the drinking water by Shipkowski, Kelly A., Sheth, Christopher M., Smith, Matthew J., Hooth, Michelle J., White, Kimber L., Germolec, Dori R.

“…Sodium dichromate dihydrate (SDD), an inorganic compound containing hexavalent chromium (Cr(VI)), is a common environmental contaminant of groundwater sources…”
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Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14 by Biggers, Jonathan W., Nguyen, Tuyen, Di, Xu, Gupton, John T., Henderson, Scott C., Emery, Sean M., Alotaibi, Moureq, White, Kimber L., Brown, Ronetta, Almenara, Jorge, Gewirtz, David A.

“…Purpose Previous studies have shown that the novel microtubule poison, JG-03-14, which binds to the colchicine binding site of tubulin, has the capacity to…”
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Immunomodulatory activity of orphan drug Elmiron® in female B6C3F1/N mice by Thakur, Sheetal A., Nyska, Abraham, White, Kimber L., Smith, Matthew J., Auttachoat, Wimolnut, Germolec, Dori R.

“…•Elmiron administration increases the numbers of splenic macrophages and NK cells in female mice.•Elmiron administration increased the macrophage phagocytosis…”
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Drinking water exposure to cadmium, an environmental contaminant, results in the exacerbation of autoimmune disease in the murine model by Leffel, Elizabeth K., Wolf, Carl, Poklis, Alphonse, White, Kimber L.

“…Cadmium is a pervasive environmental contaminant. The primary route of exposure to the general population occurs via contaminated drinking water or food…”
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Tom1l2 hypomorphic mice exhibit increased incidence of infections and tumors and abnormal immunologic response by Girirajan, Santhosh, Hauck, Paula M, Williams, Stephen, Vlangos, Christopher N, Szomju, Barbara B, Solaymani-Kohal, Sara, Mosier, Philip D, White, Kimber L. Jr, McCoy, Kathleen, Elsea, Sarah H

“…Studies have shown that the TOM1 family of proteins, including TOM1 and TOM1L1, are actively involved in endosomal trafficking and function in the immune…”
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Characterization of the T-dependent antibody response (TDAR) to keyhole limpet hemocyanin (KLH) in the Göttingen minipig by Peachee, Vanessa L, Smith, Matthew J, Beck, Melissa J, Stump, Donald G, White, Jr, Kimber L

“…Recently, there has been a renewed interest in the use of the minipig as an alternative to dogs and non-human primates for conducting toxicological assessments…”
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Jet Fuel Kerosene is not Immunosuppressive in Mice or Rats Following Inhalation for 28 Days by White, Kimber L., DeLorme, Michael P., Beatty, Patrick W., Smith, Matthew J., Peachee, Vanessa L.

“…Previous reports indicated that inhalation of JP-8 aviation turbine fuel is immunosuppressive. However, in some of those studies, the exposure concentrations…”
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Immunotoxic effects of sodium tungstate dihydrate on female B6C3F1/N mice when administered in drinking water by Frawley, Rachel P, Smith, Matthew J, White, Jr, Kimber L, Elmore, Susan A, Herbert, Ron, Moore, Rebecca, Staska, Lauren M, Behl, Mamta, Hooth, Michelle J, Kissling, Grace E, Germolec, Dori R

“…Tungsten is a naturally occurring, high-tensile strength element that has been used in a number of consumer products. Tungsten has been detected in soil,…”
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Genistein modulates immune responses and increases host resistance to B16F10 tumor in adult female B6C3F1 mice by Guo, T L, McCay, J A, Zhang, L X, Brown, R D, You, L, Karrow, N A, Germolec, D R, White, Jr, K L

“…The isoflavone genistein (4,7,4'-trihydroxyisoflavone) is a phytoestrogen found in high levels in soy products that has been associated with decreased…”
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Establishment and comparison of delayed-type hypersensitivity models in the B₆C₃F₁ mouse by Smith, Matthew J, White, Jr, Kimber L

“…The objective of these studies was to establish and compare delayed-type hypersensitivity (DTH) models, using keyhole limpet hemocyanin (KLH), sheep red blood…”
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