Search Results - "WHITACRE, C. M"
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Pharmacologic Disruption of Base Excision Repair Sensitizes Mismatch Repair-deficient and -proficient Colon Cancer Cells to Methylating Agents
Published in Clinical cancer research (01-10-1999)“…Previously we showed that a mismatch repair (MMR)-deficient cell line, HCT116 (hMLH1 mut), unlike a MMR wild-type cell line, SW480, was more resistant to the…”
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Protease activation and cleavage of poly(ADP-ribose) polymerase : An integral part of apoptosis in response to photodynamic treatment
Published in Cancer research (Chicago, Ill.) (01-03-1998)“…Apoptosis induced by numerous cancer chemotherapeutic and other toxic agents has been shown to proceed through a cascade of proteases, now termed caspases,…”
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New Isolation Technique to Study Apoptosis in Human Intestinal Epithelial Cells
Published in The American journal of pathology (01-07-1998)“…Intestinal epithelial cells derive from stem cells at the base of the crypt and migrate along the crypt-lumen axis. Their life is terminated as they reach the…”
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Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences
Published in Cancer research (Chicago, Ill.) (01-09-1995)“…We have used two different approaches to study the consequences of NAD/poly(ADP-ribose) deficiency on p53 expression and its activity in V79-derived cell…”
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Detection of Poly(ADP-ribose) Polymerase Cleavage in Response to Treatment with Topoisomerase I Inhibitors: A Potential Surrogate End Point to Assess Treatment Effectiveness
Published in Clinical cancer research (01-03-1999)“…Cleavage of poly(ADP-ribose) polymerase (PARP) by caspases is a prominent characteristic of apoptosis or programmed cell death shown to be induced by…”
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Factors affecting topotecan-induced programmed cell death : Adhesion protects cells from apoptosis and impairs cleavage of poly(ADP-ribose)polymerase
Published in Cancer research (Chicago, Ill.) (01-06-1997)“…We have evaluated the influence of anchorage status together with endogenous levels of bcl-2 family members on the ability of the topoisomerase I inhibitor,…”
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Poly(adenosine diphosphoribose) polymerase in peripheral blood leukocytes from normal donors and patients with malignancies
Published in Clinical cancer research (01-02-1995)“…A two-color flow cytometric technique was developed to analyze poly(ADP-ribose) polymerase (PADPRP) in different individuals as a function of different…”
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Oxygen free radical generation and regulation of proliferative activity of human mononuclear cells responding to different mitogens
Published in Cellular immunology (15-10-1992)“…We have compared various mitogenic stimuli for their ability to induce hydrogen peroxide (H2O2) and superoxide anion (O2-) production by PBMC and the effect of…”
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Photodynamic Therapy with the Phthalocyanine Photosensitizer Pc 4 of SW480 Human Colon Cancer Xenografts in Athymic Mice
Published in Clinical cancer research (01-05-2000)“…Photodynamic therapy (PDT) using the silicon phthalocyanine photosensitizer Pc 4[ HOSiPcOSi(CH 3 ) 2 (CH 2 ) 3 N-(CH 3 ) 2 ] is an oxidative stress associated…”
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NAD and poly(ADP-ribose) regulation of proteins involved in response to cellular stress and DNA damage
Published in Biochimie (1995)Get full text
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Topotecan increases topoisomerase IIα levels and sensitivity to treatment with etoposide in schedule-dependent process
Published in Cancer research (Chicago, Ill.) (15-04-1997)Get full text
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Involvement of blood serum in amphibian fertilization
Published in Biocell (01-04-1998)“…A proteolytic enzyme secreted by the first portion of amphibian oviduct, pars recta, called oviductin in Xenopus laevis, causes ultrastructural alterations on…”
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Nuclear DNA content of altered hepatic foci in a rat liver carcinogenesis model
Published in Cancer research (Chicago, Ill.) (01-12-1990)“…In individual altered hepatic foci (AHF), aneuploidy occurs before malignant changes can be diagnosed histologically (O. Sudilovsky and T. K. Hei. Fed. Proc.,…”
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Serum antigens detected in pars recta luminal fluid and coelomic envelope surrounding Bufo arenarum eggs
Published in Development, growth & differentiation (01-12-1996)“…In anurans, protease activity from the pars recta portion of the oviduct (under regulation by 17β‐estradiol), is known to cause ultrastructural alterations on…”
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Application of Western Blotting to the Identification of Metallothionein Binding Proteins
Published in Analytical biochemistry (01-02-1996)Get full text
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Sonication of cell extracts improves yield of p53 by immunoblotting
Published in Biocell (01-04-2000)Get more information
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Inhibition of focal adhesion kinase by antisense oligonucleotides enhances the sensitivity of breast cancer cells to camptothecins
Published in Biocell (01-04-2003)“…This study shows a strong association between cell attachment to substratum and activation of beta 1-integrin-signaling with resistance to the camptothecin…”
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Role of oviductal pars recta extract on interspecific fertilization between anurans
Published in Development, growth & differentiation (01-04-1996)“…During their journey through the oviductal pars recta, the vitelline envelope (VE) of Bufo arenarum oocytes encounter structural alterations that make them…”
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Potential involvement of C sub(3) complement factor in amphibian fertilization
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-09-2000)“…We have assessed the potential involvement of C sub(3), the third complement factor, and its receptor in Bufo arenarum fertilization. We show that a polyclonal…”
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