Search Results - "WHELAN, J"

Conversion of dietary polyunsaturated fats between humans and rodents: A review of allometric scaling models by Whelan, J., Whelan, Jay

“…•Designing of rodent diets for translational validity to humans is difficult.•Human equivalent doses in rodent diets should be used for translational…”
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Interactions between tidal turbine wakes: experimental study of a group of three-bladed rotors by Stallard, T., Collings, R., Feng, T., Whelan, J.

“…It is well known that a wake will develop downstream of a tidal stream turbine owing to extraction of axial momentum across the rotor plane. To select a…”
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Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis by Gillmore, Julian D, Maurer, Mathew S, Falk, Rodney H, Merlini, Giampaolo, Damy, Thibaud, Dispenzieri, Angela, Wechalekar, Ashutosh D, Berk, John L, Quarta, Candida C, Grogan, Martha, Lachmann, Helen J, Bokhari, Sabahat, Castano, Adam, Dorbala, Sharmila, Johnson, Geoff B, Glaudemans, Andor W.J.M, Rezk, Tamer, Fontana, Marianna, Palladini, Giovanni, Milani, Paolo, Guidalotti, Pierluigi L, Flatman, Katarina, Lane, Thirusha, Vonberg, Frederick W, Whelan, Carol J, Moon, James C, Ruberg, Frederick L, Miller, Edward J, Hutt, David F, Hazenberg, Bouke P, Rapezzi, Claudio, Hawkins, Philip N

“…BACKGROUND—Cardiac transthyretin (ATTR) amyloidosis is a progressive and fatal cardiomyopathy for which several promising therapies are in development. The…”
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Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis by Lane, Thirusha, Fontana, Marianna, Martinez-Naharro, Ana, Quarta, Candida Cristina, Whelan, Carol J, Petrie, Aviva, Rowczenio, Dorota M, Gilbertson, Janet A, Hutt, David F, Rezk, Tamer, Strehina, Svetla G, Caringal-Galima, Joan, Manwani, Richa, Sharpley, Faye A, Wechalekar, Ashutosh D, Lachmann, Helen J, Mahmood, Shameem, Sachchithanantham, Sajitha, Drage, Edmund P.S, Jenner, Harvey D, McDonald, Rosie, Bertolli, Ottavia, Calleja, Alan, Hawkins, Philip N, Gillmore, Julian D

“…BACKGROUND:Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is an increasingly recognized cause of heart failure in older individuals. We sought to…”
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Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function by Shah, Prajay T., Stratton, Jo A., Stykel, Morgan Gail, Abbasi, Sepideh, Sharma, Sandeep, Mayr, Kyle A., Koblinger, Kathrin, Whelan, Patrick J., Biernaskie, Jeff

“…Ependymal cells are multi-ciliated cells that form the brain’s ventricular epithelium and a niche for neural stem cells (NSCs) in the…”
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Application of the Nicoya OpenSPR to Studies of Biomolecular Binding: A Review of the Literature from 2016 to 2022 by Hanson, Eliza K, Whelan, Rebecca J

“…The Nicoya OpenSPR is a benchtop surface plasmon resonance (SPR) instrument. As with other optical biosensor instruments, it is suitable for the label-free…”
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T1 mapping and survival in systemic light-chain amyloidosis by Banypersad, Sanjay M, Fontana, Marianna, Maestrini, Viviana, Sado, Daniel M, Captur, Gabriella, Petrie, Aviva, Piechnik, Stefan K, Whelan, Carol J, Herrey, Anna S, Gillmore, Julian D, Lachmann, Helen J, Wechalekar, Ashutosh D, Hawkins, Philip N, Moon, James C

“…To assess the prognostic value of myocardial pre-contrast T1 and extracellular volume (ECV) in systemic amyloid light-chain (AL) amyloidosis using…”
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Strep Throat and the Backstory for PANS and PANDAS by Whelan, J Patrick

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Characterization of A11 neurons projecting to the spinal cord of mice by Koblinger, Kathrin, Füzesi, Tamás, Ejdrygiewicz, Jillian, Krajacic, Aleksandra, Bains, Jaideep S, Whelan, Patrick J

“…The hypothalamic A11 region has been identified in several species including rats, mice, cats, monkeys, zebrafish, and humans as the primary source of…”
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Ecosystem Services Provided by Birds by Whelan, Christopher J., Wenny, Daniel G., Marquis, Robert J.

“…Ecosystem services are natural processes that benefit humans. Birds contribute the four types of services recognized by the UN Millennium Ecosystem…”
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Combining the Benefits of Biotin-Streptavidin Aptamer Immobilization with the Versatility of Ni-NTA Regeneration Strategies for SPR by Hanson, Eliza K, Whelan, Rebecca J

“…The high affinity of the biotin-streptavidin interaction has made this non-covalent coupling an indispensable strategy for the immobilization and enrichment of…”
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MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress by Felder, Mildred, Kapur, Arvinder, Gonzalez-Bosquet, Jesus, Horibata, Sachi, Heintz, Joseph, Albrecht, Ralph, Fass, Lucas, Kaur, Justanjyot, Hu, Kevin, Shojaei, Hadi, Whelan, Rebecca J, Patankar, Manish S

“…Over three decades have passed since the first report on the expression of CA125 by ovarian tumors. Since that time our understanding of ovarian cancer biology…”
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Native T1 and Extracellular Volume in Transthyretin Amyloidosis by Martinez-Naharro, Ana, Kotecha, Tushar, Norrington, Karl, Boldrini, Michele, Rezk, Tamer, Quarta, Candida, Treibel, Thomas A., Whelan, Carol J., Knight, Daniel S., Kellman, Peter, Ruberg, Frederick L., Gillmore, Julian D., Moon, James C., Hawkins, Philip N., Fontana, Marianna

“…This study evaluated the prognostic potential of native myocardial T1 in cardiac transthyretin amyloidosis (ATTR) and compared native T1 with extracellular…”
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Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis by Fontana, Marianna, Pica, Silvia, Reant, Patricia, Abdel-Gadir, Amna, Treibel, Thomas A, Banypersad, Sanjay M, Maestrini, Viviana, Barcella, William, Rosmini, Stefania, Bulluck, Heerajnarain, Sayed, Rabya H, Patel, Ketna, Mamhood, Shameem, Bucciarelli-Ducci, Chiara, Whelan, Carol J, Herrey, Anna S, Lachmann, Helen J, Wechalekar, Ashutosh D, Manisty, Charlotte H, Schelbert, Eric B, Kellman, Peter, Gillmore, Julian D, Hawkins, Philip N, Moon, James C

“…BACKGROUND—The prognosis and treatment of the 2 main types of cardiac amyloidosis, immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are…”
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Noncontrast T1 Mapping for the Diagnosis of Cardiac Amyloidosis by Karamitsos, Theodoros D., MD, PhD, Piechnik, Stefan K., PhD, MScEE, Banypersad, Sanjay M., MBChB, Fontana, Marianna, MD, Ntusi, Ntobeko B., MBChB, Ferreira, Vanessa M., MD, Whelan, Carol J., MD, Myerson, Saul G., MD, Robson, Matthew D., PhD, Hawkins, Philip N., PhD, Neubauer, Stefan, MD, Moon, James C., MD

“…Objectives This study sought to explore the potential role of noncontrast myocardial T1 mapping for detection of cardiac involvement in patients with primary…”
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Long-Term Results of Hypofractionated Radiation Therapy for Breast Cancer by Whelan, Timothy J, Pignol, Jean-Philippe, Levine, Mark N, Julian, Jim A, MacKenzie, Robert, Parpia, Sameer, Shelley, Wendy, Grimard, Laval, Bowen, Julie, Lukka, Himu, Perera, Francisco, Fyles, Anthony, Schneider, Ken, Gulavita, Sunil, Freeman, Carolyn

“…The optimal schedule of radiation treatment after breast-conserving surgery for invasive breast cancer is unknown. In this study, two groups of patients…”
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Entrustment Decision Making: Extending Miller’s Pyramid by ten Cate, Olle, Carraccio, Carol, Damodaran, Arvin, Gofton, Wade, Hamstra, Stanley J., Hart, Danielle E., Richardson, Denyse, Ross, Shelley, Schultz, Karen, Warm, Eric J., Whelan, Alison J., Schumacher, Daniel J.

“…The iconic Miller’s pyramid, proposed in 1989, characterizes 4 levels of assessment in medical education (“knows,” “knows how,” “shows how,” “does”). The frame…”
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Structure of a rabies virus polymerase complex from electron cryo-microscopy by Horwitz, Joshua A., Jenni, Simon, Harrison, Stephen C., Whelan, Sean P. J.

“…Nonsegmented negative-stranded (NNS) RNA viruses, among them the virus that causes rabies (RABV), include many deadly human pathogens. The large polymerase (L)…”
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TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes by Zang, Ruochen, Gomez Castro, Maria Florencia, McCune, Broc T, Zeng, Qiru, Rothlauf, Paul W, Sonnek, Naomi M, Liu, Zhuoming, Brulois, Kevin F, Wang, Xin, Greenberg, Harry B, Diamond, Michael S, Ciorba, Matthew A, Whelan, Sean P J, Ding, Siyuan

“…Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19 patients. However, it is unclear whether SARS-CoV-2…”
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STING-dependent translation inhibition restricts RNA virus replication by Franz, Kate M., Neidermyer, William J., Tan, Yee-Joo, Whelan, Sean P. J., Kagan, Jonathan C.

“…In mammalian cells, IFN responses that occur during RNA and DNA virus infections are activated by distinct signaling pathways. The RIG-I–like-receptors (RLRs)…”
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