Search Results - "WHATLEY, R. E"

Inflammatory roles of P-selectin by LORANT, D. E, TOPHAM, M. K, WHATLEY, R. E, MCEVER, R. P, MCINTYRE, T. M, PRESCOTT, S. M, ZIMMERMAN, G. A

“…Polymorphonuclear leukocytes (PMNs) bind rapidly and reversibly to endothelial cells induced to express P-selectin, a glycoprotein that mediates adhesive…”
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Inhaled nitric oxide versus conventional therapy: Effect on oxygenation in ARDS by MICHAEL, J. R, BARTON, R. G, LIOU, T. G, SAMUELSON, W. M, CARVETH, H. J, HINSON, D. M, MORRIS, S. E, DAVIS, B. L, DAY, R. W, SAFFLE, J. R, MONE, M, MARKEWITZ, B. A, HILLIER, K, ELSTAD, M. R, CAMPBELL, E. J, TROYER, B. E, WHATLEY, R. E

“…A randomized, controlled clinical trial was performed with patients with acute respiratory distress syndrome (ARDS) to compare the effect of conventional…”
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Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion by LEWIS, M. S, WHATLEY, R. E, CAIN, P, MCINTYRE, T. M, PRESCOTT, S. M, ZIMMERMAN, G. A

“…Oxidant-induced damage to the intima of pulmonary and systemic vessels is thought to be an important mechanism of injury in a variety of syndromes of vascular…”
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The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C by WHATLEY, R. E, NELSON, P, ZIMMERMAN, G. A, STEVENS, D. L, PARKER, C. J, MCINTYRE, T. M, PRESCOTT, S. M

“…Endothelial cells (EC) synthesize platelet-activating factor (PAF) when stimulated with agonists that bind to cell-surface receptors. We examined events that…”
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P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage by Fujimoto, T., Stroud, E., Whatley, R.E., Prescott, S.M., Muszbek, L., Laposata, M., McEver, R.P.

“…We report that the adhesion receptor P-selectin can be metabolically labeled with [3H]palmitic acid in human platelets. Analysis of alkaline methanolysis…”
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Endothelial selectins in acute mountain sickness and high-altitude pulmonary edema by Grissom, C K, Zimmerman, G A, Whatley, R E

“…Mechanical or inflammatory injury to pulmonary endothelial cells may cause impaired pulmonary gas exchange in acute mountain sickness (AMS) and noncardiogenic…”
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Growth-dependent changes in arachidonic acid release from endothelial cells are mediated by protein kinase C and changes in diacylglycerol by WHATLEY, R. E, STROUD, E. D, BUNTING, M, ZIMMERMAN, G. A, MCINTYRE, T. M, PRESCOTT, S. M

“…When stimulated, endothelial cells release arachidonic acid from phospholipids and oxidize it to eicosanoids. The rate-limiting step in this pathway is the…”
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Synthesis of platelet-activating factor by endothelial cells. The role of G proteins by WHATLEY, R. E, FENNELL, D. F, KURRUS, J. A, ZIMMERMAN, G. A, MCINTYRE, T. M, PRESCOTT, S. M

“…Production of the potent lipid autacoid, platelet-activating factor (PAF), is a stimulated response of the endothelium which has important physiologic…”
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Activation of the acetyl-coenzyme A:lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells by HOLLAND, M. R, VENABLE, M. E, WHATLEY, R. E, ZIMMERMAN, G. A, MCINTYRE, T. M, PRESCOTT, S. M

“…Platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF) is a phospholipid with many physiological actions. It is synthesized by…”
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Lipid metabolism and signal transduction in endothelial cells by Whatley, R E, Zimmerman, G A, McIntyre, T M, Prescott, S M

“…Endothelial cells have the capacity to metabolize several important lipids; this includes the ability to store and then metabolize arachidonate, as well as the…”
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Prolonged hypofibrinogenemia and protein C activation after envenoming by Echis carinatus sochureki by Weis, J R, Whatley, R E, Glenn, J L, Rodgers, G M

“…Following envenomization by Echis carinatus sochureki, a professional snake handler developed a profound coagulopathy manifested by hemorrhage from the bite…”
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Endothelial cells for studies of platelet-activating factor and arachidonate metabolites by Zimmerman, G A, Whatley, R E, McIntyre, T M, Benson, D M, Prescott, S M

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Production of platelet-activating factor by endothelial cells by Whatley, R E, Zimmerman, G A, McIntyre, T M, Taylor, R, Prescott, S M

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Endothelial cells reestablish functional integrity after reversible permeabilization by FENNELL, D. F, WHATLEY, R. E, MCINTYRE, T. M, PRESCOTT, S. M, ZIMMERMAN, G. A

“…Permeabilization is an important tool in cell biology that allows manipulation of intracellular mechanisms by introduction of probes and regulatory molecules…”
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Regulation of platelet-activating factor (PAF) synthesis and PAF-mediated neutrophil adhesion to endothelial cells activated by thrombin by Carveth, H J, Shaddy, R E, Whatley, R E, McIntyre, T M, Prescott, S M, Zimmerman, G A

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Endothelium from diverse vascular sources synthesizes platelet-activating factor by Whatley, R E, Zimmerman, G A, McIntyre, T M, Prescott, S M

“…Stimulation of cultured bovine endothelial cells from aorta, pulmonary artery, coronary artery, and vena cava with calcium ionophore A23187, adenosine…”
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Proliferation-dependent changes in release of arachidonic acid from endothelial cells by Whatley, R E, Satoh, K, Zimmerman, G A, McIntyre, T M, Prescott, S M

“…Stimulation of endothelial cells resulted in release of arachidonic acid from phospholipids. The magnitude of this response decreased as the cells became…”
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Proliferation-dependent changes in release of arachidonic acid from endothelial cells by Whatley, R E, Satoh, K, Zimmerman, G A, McIntyre, T M, Prescott, S M

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Production of platelet-activating factor, a biologically active lipid, by vascular endothelial cells by Zimmerman, G A, Whatley, R E, McIntyre, T M, Prescott, S M

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The Regulation of Platelet-activating Factor Production in Endothelial Cells by Whatley, R E, Nelson, P, Zimmerman, G A, Stevens, D L, Parker, C J, McIntyre, T M, Prescott, S M

“…Endothelial cells (EC) synthesize platelet-activating factor (PAF) when stimulated with agonists that bind to cell-surface receptors. We examined events that…”
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