Search Results - "WEYANT, Michael J"

Toll-Like Receptor-4 Is a Mediator of Proliferation in Esophageal Adenocarcinoma by Kohtz, Patrick D., Halpern, Alison L., Eldeiry, Mohamed A., Hazel, Kweku, Kalatardi, Shana, Ao, Lihua, Meng, Xianzhong, Reece, T. Brett, Fullerton, David A., Weyant, Michael J.

“…Chronic inflammation from reflux disease has been implicated as part of the development of esophageal adenocarcinoma. Toll-like receptors (TLRs), a component…”
Get full text

Simvastatin down-regulates osteogenic response in cultured human aortic valve interstitial cells by Jarrett, Michael J., Yao, Qingzhou, Venardos, Neil, Weyant, Michael J., Reece, T. Brett, Meng, Xianzhong, Fullerton, David A.

“…Aortic valve interstitial cells have been implicated in the pathogenesis of aortic stenosis. In response to proinflammatory stimuli, aortic valve interstitial…”
Get full text

Toll-Like Receptor 4–Dependent Microglial Activation Mediates Spinal Cord Ischemia–Reperfusion Injury by Bell, Marshall T., Puskas, Ferenc, Agoston, Viktor A., Cleveland, Joseph C., Freeman, Kirsten A., Gamboni, Fabia, Herson, Paco S., Meng, Xianzhong, Smith, Phillip D., Weyant, Michael J., Fullerton, David A., Reece, T. Brett

“…BACKGROUND—Paraplegia continues to complicate thoracoabdominal aortic interventions. The elusive mechanism of spinal cord ischemia–reperfusion injury has…”
Get full text

Thoracoscopic Lobectomy and Segmentectomy for Infectious Lung Disease by Mitchell, John D., MD, Yu, Jessica A., MD, Bishop, Amy, BA, Weyant, Michael J., MD, Pomerantz, Marvin, MD

“…Background The potential benefits of thoracoscopic lobectomy and segmentectomy for early stage non–small cell lung cancer have been well documented in the…”
Get full text

The Evolution of Chemokine Release Supports a Bimodal Mechanism of Spinal Cord Ischemia and Reperfusion Injury by SMITH, Phillip D, PUSKAS, Ferenc, XIANZHONG MENG, LEE, Joon H, CLEVELAND, Joseph C, WEYANT, Michael J, FULLERTON, David A, BRETT REECE, T

“…Paraplegia remains a devastating complication of thoracic aortic surgery. The mechanism of the antecedent spinal cord ischemia and reperfusion injury (IR)…”
Get full text

Anatomic Lung Resection for Nontuberculous Mycobacterial Disease by Mitchell, John D., MD, Bishop, Amy, Cafaro, Amanda, RN, BSN, Weyant, Michael J., MD, Pomerantz, Marvin, MD

“…Background Chronic lung infections involving nontuberculous mycobacteria are often inadequately treated owing to concomitant lung parenchymal damage, leading…”
Get full text

Extended post ex-vivo lung perfusion cold preservation predicts primary graft dysfunction and mortality: Results from a multicentric study by Leiva-Juárez, Miguel M., Urso, Andreacarola, Arango Tomás, Elisabet, Lederer, David J., Sanchez, Pablo, Griffith, Bartley, Davis, R. Duane, Daneshmand, Mani, Hartwig, Matthew, Cantu, Edward, Weyant, Michael J., Bermudez, Christian, D'Cunha, Jonathan, Machuca, Tiago, Wozniak, Thomas, Lynch, William, Nemeh, Hassan, Mulligan, Michael, Song, Tae, Jessen, Michael, Camp, Phillip C., Caldeira, Christiano, Whitson, Bryan, Kreisel, Daniel, Ramzy, Danny, D'Ovidio, Frank

“…Ex vivo lung perfusion (EVLP) allows for a reassessment of lung grafts initially deemed unsuitable for transplantation, increasing the available donor pool;…”
Get full text

Cytokine Expression Profile in Human Lungs Undergoing Normothermic Ex-Vivo Lung Perfusion by Sadaria, Miral R., MD, Smith, Phillip D., MD, Fullerton, David A., MD, Justison, George A., BS, CCP, LP, Lee, Joon H., MD, Puskas, Ferenc, MD, PhD, Grover, Frederick L., MD, Cleveland, Joseph C., MD, Reece, T. Brett, MD, Weyant, Michael J., MD

“…Background A donor lung shortage prevents patients from receiving life-saving transplants. Ex-vivo lung perfusion (EVLP) is a viable means of expanding the…”
Get full text

Clinical predictors of in‐hospital mortality in venoarterial extracorporeal membrane oxygenation by Vigneshwar, Navin G., Kohtz, Patrick D., Lucas, Mark T., Bronsert, Michael, Weyant, Michael, Masood, Muhammad, Itoh, Akinobu, Rove, Jessica Y., Reece, Thomas B., Cleveland, Joseph C., Pal, Jay D., Fullerton, David A., Aftab, Muhammad

“…Introduction Venoarterial extracorporeal membrane oxygenation (VA‐ECMO) is utilized as a life‐saving procedure and bridge to myocardial recovery for patients…”
Get full text

Aortic valve calcification is mediated by a differential response of aortic valve interstitial cells to inflammation by Venardos, Neil, MD, Nadlonek, Nicole A., MD, Zhan, Qiong, MD, Weyant, Michael J., MD, Reece, Thomas Brett, MD, Meng, Xianzhong, MD, PhD, Fullerton, David A., MD

“…Abstract Background Although calcific aortic stenosis is common, calcification of the other three heart valves is not. The aortic valve interstitial cell (VIC)…”
Get full text

Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosis by Meng, Xianzhong, Ao, Lihua, Song, Yong, Babu, Ashok, Yang, Xiaoping, Wang, Maorong, Weyant, Michael J, Dinarello, Charles A, Cleveland, Jr, Joseph C, Fullerton, David A

“…Calcific aortic valve stenosis is the most common indication for surgical valve replacement. Inflammation appears to be one of the mechanisms involved in…”
Get more information

A novel technique of robotic preperitoneal approach for Morgagni hernia repair by Gergen, Anna K., Frankel, John H., Weyant, Michael J., Pratap, Akshay

“…Introduction Morgagni hernia (MH) is a rare, congenital diaphragmatic hernia. We developed a novel robotic‐assisted technique to repair MH which enables…”
Get full text

Knockdown of secretory phospholipase A2 IIa reduces lung cancer growth in vitro and in vivo by Yu, Jessica A., MD, Mauchley, David, MD, Li, Howard, MD, Meng, Xianzhong, MD, PhD, Nemenoff, Raphael A., PhD, Fullerton, David A., MD, Weyant, Michael J., MD

“…Objective Group IIa secretory phospholipase A2 (sPLA2 IIa) plays a role in the malignant potential of several epithelial cancers. Nuclear factor kappa B…”
Get full text

Radiation induces osteogenesis in human aortic valve interstitial cells by Nadlonek, Nicole A., MD, Weyant, Michael J., MD, Yu, Jessica A., MD, Cleveland, Joseph C., MD, Reece, T. Brett, MD, Meng, Xianzhong, MD, PhD, Fullerton, David A., MD

“…Objective Irradiation of the chest or chest wall has been shown to cause calcific aortic stenosis. However, the mechanisms are unknown. Aortic valve…”
Get full text

Interleukin-1 Beta Induces an Inflammatory Phenotype in Human Aortic Valve Interstitial Cells Through Nuclear Factor Kappa Beta by Nadlonek, Nicole, MD, Lee, Joon H., MD, Reece, T. Brett, MD, Weyant, Michael J., MD, Cleveland, Joseph C., MD, Meng, Xianzhong, MD, PhD, Fullerton, David A., MD

“…Background Mechanisms of inflammation have been implicated in the pathogenesis of aortic stenosis. When stimulated, human aortic valve interstitial cells…”
Get full text

Matrix Gla protein regulates calcification of the aortic valve by Venardos, Neil, MD, Bennett, Daine, MD, Weyant, Michael J., MD, Reece, Thomas Brett, MD, Meng, Xianzhong, MD, PhD, Fullerton, David A., MD

“…Abstract Background The aortic valve interstitial cell (AVIC) has been implicated in the pathogenesis of aortic stenosis. In response to proinflammatory…”
Get full text

Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers by Kastelowitz, Noah, Marsh, Megan D, McCarter, Martin, Meguid, Robert A, Bhardwaj, Narine Wandrey, Mitchell, John D, Weyant, Michael J, Scott, Christopher, Schefter, Tracey, Stumpf, Priscilla, Leong, Stephen, Messersmith, Wells, Lieu, Christopher, Leal, Alexis D, Davis, S Lindsey, Purcell, William T, Kane, Madeleine, Wani, Sachin, Shah, Raj, Hammad, Hazem, Edmundowicz, Steven, Goodman, Karyn A

“…The impact of radiation prescription dose on postoperative complications during standard of care trimodality therapy for operable stage II-III esophageal and…”
Get full text

Preservation of Motor Function After Spinal Cord Ischemia and Reperfusion Injury Through Microglial Inhibition by Smith, Phillip D., MD, Bell, Marshall T., MD, Puskas, Ferenc, MD, PhD, Meng, Xianzhong, MD, PhD, Cleveland, Joseph C., MD, Weyant, Michael J., MD, Fullerton, David A., MD, Reece, T. Brett, MD

“…Background Paraplegia remains a devastating complication of thoracoabdominal aortic procedures resulting from spinal cord ischemia and reperfusion injury…”
Get full text

Statin therapy attenuates growth and malignant potential of human esophageal adenocarcinoma cells by Sadaria, Miral R., MD, Reppert, Amy E., MD, Yu, Jessica A., MD, Meng, Xianzhong, MD, PhD, Fullerton, David A., MD, Reece, T. Brett, MD, Weyant, Michael J., MD

“…Objectives Esophageal adenocarcinoma is an aggressive malignancy generally diagnosed after metastatic spread and currently lacks effective medical therapy…”
Get full text

Spinal cord protection via alpha-2 agonist-mediated increase in glial cell-line–derived neurotrophic factor by Freeman, Kirsten A., MD, Fullerton, David A., MD, Foley, Lisa S., MD, Bell, Marshall T., MD, Cleveland, Joseph C., MD, Weyant, Michael J., MD, Mares, Joshua, BA, Meng, Xianzhong, PhD, MD, Puskas, Ferenc, MD, PhD, Reece, T. Brett, MD

“…Abstract Objectives Delayed paraplegia secondary to ischemia–reperfusion injury is a devastating complication of thoracoabdominal aortic surgery. Alpha-2…”
Get full text