Search Results - "WESTHOF, E"

Prediction of nucleic acid binding probability in proteins: a neighboring residue network based score by Miao, Zhichao, Westhof, Eric

“…We describe a general binding score for predicting the nucleic acid binding probability in proteins. The score is directly derived from physicochemical and…”
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The interaction networks of structured RNAs by Lescoute, A., Westhof, E.

“…All pairwise interactions occurring between bases which could be detected in three-dimensional structures of crystallized RNA molecules are annotated on new…”
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Crystal Structure of Paromomycin Docked into the Eubacterial Ribosomal Decoding A Site by Vicens, Quentin, Westhof, Eric

“…Background: Aminoglycoside antibiotics interfere with translation in both gram-positive and gram-negative bacteria by binding to the tRNA decoding A site of…”
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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding by François, Boris, Russell, Rupert J. M., Murray, James B., Aboul-ela, Fareed, Masquida, Benoît, Vicens, Quentin, Westhof, Eric

“…The crystal structures of six complexes between aminoglycoside antibiotics (neamine, gentamicin C1A, kanamycin A, ribostamycin, lividomycin A and neomycin B)…”
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A molecular dynamics simulation study of an aminoglycoside/A-site RNA complex: conformational and hydration patterns by Vaiana, A.C., Westhof, E., Auffinger, P.

“…Aminoglycoside antibiotics interfere with the translation mechanism by binding to the tRNA decoding site of the 16S ribosomal RNA. Crystallographic structures…”
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Docking of Aminoglycosides to Hydrated and Flexible RNA by Moitessier, Nicolas, Westhof, Eric, Hanessian, Stephen

“…Although much effort has been devoted to the development of programs suited for the docking of ligands to proteins, much less progress has been achieved in the…”
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Two conformational states in the crystal structure of the Homo sapiens cytoplasmic ribosomal decoding A site by Kondo, Jiro, Urzhumtsev, Alexandre, Westhof, Eric

“…The decoding A site of the small ribosomal subunit is an RNA molecular switch, which monitors codon–anticodon interactions to guarantee translation fidelity…”
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A standard reference frame for the description of nucleic acid base-pair geometry by Olson, W K, Bansal, M, Burley, S K, Dickerson, R E, Gerstein, M, Harvey, S C, Heinemann, U, Lu, X J, Neidle, S, Shakked, Z, Sklenar, H, Suzuki, M, Tung, C S, Westhof, E, Wolberger, C, Berman, H M

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The RNA polymerase III-dependent family of genes in hemiascomycetes: comparative RNomics, decoding strategies, transcription and evolutionary implications by Marck, Christian, Kachouri-Lafond, Rym, Lafontaine, Ingrid, Westhof, Eric, Dujon, Bernard, Grosjean, Henri

“…We present the first comprehensive analysis of RNA polymerase III (Pol III) transcribed genes in ten yeast genomes. This set includes all tRNA genes (tDNA) and…”
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Large telomerase RNA, telomere length heterogeneity and escape from senescence in Candida glabrata by Kachouri-Lafond, R., Dujon, B., Gilson, E., Westhof, E., Fairhead, C., Teixeira, M.T.

“…Telomerase, the key enzyme essential for the maintenance of eukaryotic chromosome ends, contains a reverse transcriptase and an RNA that provides the template…”
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Motif prediction in ribosomal RNAs Lessons and prospects for automated motif prediction in homologous RNA molecules by Leontis, N.B, Stombaugh, J, Westhof, E

“…The traditional way to infer RNA secondary structure involves an iterative process of alignment and evaluation of covariation statistics between all positions…”
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The interactions between guanine and uracil by Westhof, E.

“…Abstract only…”
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The A-minor motifs in the decoding recognition process by Lescoute, A., Westhof, E.

“…The formation of A-minor motifs, mediated by adenines binding into the shallow/minor groove of stacked and helical Watson–Crick base pairs, is described. The…”
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Assembly of Core Helices and Rapid Tertiary Folding of a Small Bacterial Group I Ribozyme by Rangan, Prashanth, Masquida, Benoît, Westhof, Eric, Woodson, Sarah A.

“…Compact but non-native intermediates have been implicated in the hierarchical folding of several large RNAs, but there is little information on their…”
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An mRNA Is Capped by a 2',5' Lariat Catalyzed by a Group I-like Ribozyme by Nielsen, Henrik, Westhof, Eric, Johansen, Steinar

“…Twin-ribozyme introns are formed by two ribozymes belonging to the group I family and occur in some ribosomal RNA transcripts. The group I-like ribozyme, GIR1,…”
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Group I introns and RNA folding by Westhof, E

“…Before the discovery of catalytic RNA, tRNA molecules were the most studied RNA molecules for understanding RNA folding. Afterwards, group I introns, because…”
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Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the γ-amino-α-hydroxybutyryl (haba) group by Kondo, Jiro, François, Boris, Russell, Rupert J.M., Murray, James B., Westhof, Eric

“…Amikacin is the 4,6-linked aminoglycoside modified at position N1 of the 2-deoxystreptamine ring (ring II) by the L-haba group. In the present study, the…”
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Binding of Neomycin-Class Aminoglycoside Antibiotics to Mutant Ribosomes with Alterations in the A Site of 16S rRNA by HOBBIE, Sven N, PFISTER, Peter, BRUELL, Christian, SANDER, Peter, FRANCOIS, Boris, WESTHOF, Eric, BÖTTGER, Erik C

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis of the Contribution of Individual Substituents in 4,6-Aminoglycoside-Ribosome Interaction by HOBBLE, Sven N, PFISTER, Peter, BRÜLL, Christian, WESTHOF, Eric, BÖTTGER, Erik C

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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MANIP: An interactive tool for modelling RNA by Massire, C, Westhof, E

“…Large RNA structures can be viewed as assemblies of smaller units or modules that are usually clearly identified (helices, hairpin loops, other recurrent…”
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