Search Results - "WESTERHOF, NICO"

The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension by Vonk Noordegraaf, Anton, MD, PhD, Westerhof, Berend E., PhD, Westerhof, Nico, PhD

“…Abstract In pulmonary hypertension, the right ventricle adapts to the increasing vascular load by enhancing contractility (“coupling”) to maintain flow…”
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The effects of exercise on right ventricular contractility and right ventricular-arterial coupling in pulmonary hypertension by Spruijt, Onno A, de Man, Frances S, Groepenhoff, Herman, Oosterveer, Frank, Westerhof, Nico, Vonk-Noordegraaf, Anton, Bogaard, Harm-Jan

“…Exercise tolerance is decreased in patients with pulmonary hypertension (PH). It is unknown whether exercise intolerance in PH coincides with an impaired…”
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Treatment strategies for the right heart in pulmonary hypertension by Westerhof, Berend E, Saouti, Nabil, van der Laarse, Willem J, Westerhof, Nico, Vonk Noordegraaf, Anton

“…The function of the right ventricle (RV) determines the prognosis of patients with pulmonary hypertension. While much progress has been made in the treatment…”
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Progressive Right Ventricular Dysfunction in Patients With Pulmonary Arterial Hypertension Responding to Therapy by van de Veerdonk, Mariëlle C., MD, Kind, Taco, MD, Marcus, J. Tim, PhD, Mauritz, Gert-Jan, MSc, Heymans, Martijn W., PhD, Bogaard, Harm-Jan, MD, PhD, Boonstra, Anco, MD, PhD, Marques, Koen M.J., MD, PhD, Westerhof, Nico, PhD, Vonk-Noordegraaf, Anton, MD, PhD

“…Objectives The purpose of this study was to examine the relationship between changes in pulmonary vascular resistance (PVR) and right ventricular ejection…”
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Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension by Trip, Pia, Rain, Silvia, Handoko, M Louis, van der Bruggen, Cathelijne, Bogaard, Harm J, Marcus, J Tim, Boonstra, Anco, Westerhof, Nico, Vonk-Noordegraaf, Anton, de Man, Frances S

“…Right ventricular (RV) diastolic stiffness is increased in pulmonary arterial hypertension (PAH) patients. We investigated whether RV diastolic stiffness is…”
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Right ventricular ejection fraction is better reflected by transverse rather than longitudinal wall motion in pulmonary hypertension by Kind, Taco, Mauritz, Gert-Jan, Marcus, J Tim, van de Veerdonk, Mariëlle, Westerhof, Nico, Vonk-Noordegraaf, Anton

“…Longitudinal wall motion of the right ventricle (RV), generally quantified as tricuspid annular systolic excursion (TAPSE), has been well studied in pulmonary…”
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Progressive Changes in Right Ventricular Geometric Shortening and Long-term Survival in Pulmonary Arterial Hypertension by Mauritz, Gert-Jan, MSc, Kind, Taco, MD, Marcus, J. Tim, PhD, Bogaard, Harm-Jan, MD, PhD, van de Veerdonk, Mariëlle, MD, Postmus, Pieter E., MD, PhD, FCCP, Boonstra, Anco, MD, PhD, Westerhof, Nico, PhD, Vonk-Noordegraaf, Anton, MD, PhD

“…Background Until now, many investigators have focused on describing right ventricular (RV) dysfunction in groups of patients with pulmonary arterial…”
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A review of methods to determine the functional arterial parameters stiffness and resistance by Westerhof, Nico, Westerhof, Berend E

“…In treatment of hypertension not only the pressure response is of interest, but also the effect on arterial parameters, for example, stiffness and resistance,…”
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Severely reduced diffusion capacity in idiopathic pulmonary arterial hypertension: patient characteristics and treatment responses by TRIP, Pia, NOSSENT, Esther J, VONK-NOORDEGRAAF, Anton, DE MAN, Frances S, VAN DEN BERK, Inge A. H, BOONSTRA, Anco, GROEPENHOFF, Herman, LETER, Edward M, WESTERHOF, Nico, GRÜNBERG, Katrien, BOGAARD, Harm-Jan

“…A subgroup of patients with idiopathic pulmonary arterial hypertension (IPAH) has severely reduced diffusing capacity of the lung for carbon monoxide (DLCO)…”
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Signs of Right Ventricular Deterioration in Clinically Stable Patients With Pulmonary Arterial Hypertension by van de Veerdonk, Mariëlle C., MD, Marcus, J. Tim, PhD, Westerhof, Nico, PhD, de Man, Frances S., PhD, Boonstra, Anco, MD, PhD, Heymans, Martijn W., PhD, Bogaard, Harm-Jan, MD, PhD, Vonk Noordegraaf, Anton, MD, PhD

“…Abstract BACKGROUND: Even after years of stable response to therapy, patients with idiopathic pulmonary arterial hypertension (IPAH) may show an unexpected…”
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Upfront combination therapy reduces right ventricular volumes in pulmonary arterial hypertension by van de Veerdonk, Mariëlle C, Huis In T Veld, Anna E, Marcus, J Tim, Westerhof, Nico, Heymans, Martijn W, Bogaard, Harm-Jan, Vonk-Noordegraaf, Anton

“…In pulmonary arterial hypertension (PAH), upfront combination therapy is associated with better clinical outcomes and a greater reduction in N-terminal…”
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Cross-Talk Between Cardiac Muscle and Coronary Vasculature by Westerhof, Nico, Boer, Christa, Lamberts, Regis R, Sipkema, Pieter

“…Laboratory for Physiology and Department of Anesthesiology, Institute for Cardiovascular Research Vrije Universiteit, VU University Medical Center, Amsterdam,…”
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P137 Reflections Revisited: Reinterpretation Required by Westerhof, Berend, Westerhof, Nico

“…Introduction Pressure waveshape derived parameters such as the augmentation index are related to unfavourable cardiovascular events [ 1 ]. Wave reflections…”
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Early return of reflected waves increases right ventricular wall stress in chronic thromboembolic pulmonary hypertension by Fukumitsu, Masafumi, Westerhof, Berend E, Ruigrok, Dieuwertje, Braams, Natalia J, Groeneveldt, Joanne A, Bayoumy, Ahmed A, Marcus, J Tim, Meijboom, Lilian J, de Man, Frances S, Westerhof, Nico, Bogaard, Harm-Jan, Vonk Noordegraaf, Anton

“…Pulmonary vascular resistance (PVR) and compliance are comparable in proximal and distal chronic thromboembolic pulmonary hypertension (CTEPH). However,…”
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Systolic Hypertension Mechanisms: Effect of Global and Local Proximal Aorta Stiffening on Pulse Pressure by Reymond, Philippe, Westerhof, Nico, Stergiopulos, Nikos

“…Decrease in arterial compliance leads to an increased pulse pressure, as explained by the Windkessel effect. Pressure waveform is the sum of a forward running…”
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Contribution of the Arterial System and the Heart to Blood Pressure during Normal Aging - A Simulation Study by Maksuti, Elira, Westerhof, Nico, Westerhof, Berend E, Broomé, Michael, Stergiopulos, Nikos

“…During aging, systolic blood pressure continuously increases over time, whereas diastolic pressure first increases and then slightly decreases after middle…”
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Accurate assessment of load-independent right ventricular systolic function in patients with pulmonary hypertension by Trip, Pia, MD, Kind, Taco, MD, PhD, van de Veerdonk, Marielle C., MD, Marcus, Johannes T., PhD, de Man, Frances S., PhD, Westerhof, Nico, PhD, Vonk-Noordegraaf, Anton, MD, PhD

“…Background End-systolic elastance (Ees ), a load-independent measure of ventricular function, is of clinical interest for studies of the right ventricle (RV)…”
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Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension by Gan, C Tji-Joong, Lankhaar, Jan-Willem, Westerhof, Nico, Marcus, J Tim, Becker, Annemarie, Twisk, Jos W R, Boonstra, Anco, Postmus, Pieter E, Vonk-Noordegraaf, Anton

“…Decreased total compliance of the pulmonary vascular bed is associated with increased mortality in patients with pulmonary arterial hypertension (PAH). We…”
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Clinically Significant Change in Stroke Volume in Pulmonary Hypertension by van Wolferen, Serge A., MD, van de Veerdonk, Marielle C., BSc, Mauritz, Gert-Jan, BSc, Jacobs, Wouter, MD, Marcus, J. Tim, PhD, Marques, Koen M.J., MD, Bronzwaer, Jean G.F., MD, PhD, Heymans, Martijn W., PhD, Boonstra, Anco, MD, PhD, Postmus, Pieter E., MD, PhD, FCCP, Westerhof, Nico, PhD, Vonk Noordegraaf, Anton, MD, PhD

“…Background Stroke volume is probably the best hemodynamic parameter because it reflects therapeutic changes and contains prognostic information in pulmonary…”
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Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension by de Man, Frances S, Handoko, M Louis, van Ballegoij, Joris J M, Schalij, Ingrid, Bogaards, Sylvia J P, Postmus, Pieter E, van der Velden, Jolanda, Westerhof, Nico, Paulus, Walter J, Vonk-Noordegraaf, Anton

“…In pulmonary arterial hypertension (PH), sympathetic adrenergic activity is highly elevated. Sympathetic overactivity is a compensatory mechanism at first, but…”
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