Search Results - "WESSEL, G. M"

The double-edged sword of the mammalian oocyte--advantages, drawbacks and approaches for basic and clinical analysis at the single cell level by Brayboy, L M, Wessel, G M

“…Oocytes are usually the largest cells in the body and as such offer unique opportunities for single-cell analysis. Unfortunately, these cells are also some of…”
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The double-edged sword of the mammalian oocyte--advantages, drawbacks and approaches for basic and clinical analysis at the single cell level by Brayboy, L M, Wessel, G M

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A Molecular Analysis of Hyalin—A Substrate for Cell Adhesion in the Hyaline Layer of the Sea Urchin Embryo by Wessel, Gary M., Berg, Linnea, Adelson, David L., Cannon, Gail, McClay, David R.

“…The hyaline layer of echinoderm embryos is an extraembryonic matrix that functions as a substrate for cell adhesion through early development. The major…”
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The Exocytosis Regulatory Proteins Syntaxin and VAMP Are Shed from Sea Urchin Sperm during the Acrosome Reaction by Schulz, J.R., Wessel, G.M., Vacquier, V.D.

“…Syntaxin is a cytoplasmically oriented plasma membrane protein and VAMP (vesicle-associated membrane protein; synaptobrevin) is a protein associated with the…”
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SFE1, a Constituent of the Fertilization Envelope in the Sea Urchin Is Made by Oocytes and Contains Low-Density Lipoprotein-Receptor-Like Repeats by WESSEL, Gary M, CONNER, Sean, LAIDLAW, Michael, HARRISON, Jacob, LAFLEUR, Gary J, JR

“…At fertilization in most animals, cortical granules of the egg or oocyte secrete their contents, whose function it is to modify the extracellular matrix. This…”
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Cortical granule biogenesis is active throughout oogenesis in sea urchins by LAIDLAW, M, WESSEL, G. M

“…Cortical granules are secretory vesicles formed in the eggs of most animals and are essential for the prevention of polyspermy in these organisms. We have…”
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The Major Yolk Protein in Sea Urchins Is a Transferrin-like, Iron Binding Protein by Brooks, Jacqueline M., Wessel, Gary M.

“…The major yolk protein (MYP) in sea urchins has historically been classified as a vitellogenin based on its abundance in the yolk platelets. Curiously, it is…”
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Cortical granule translocation is microfilament mediated and linked to meiotic maturation in the sea urchin oocyte by Wessel, Gary M, Conner, Sean D, Berg, Linnea

“…Cortical granules exocytose after the fusion of egg and sperm in most animals, and their contents function in the block to polyspermy by creating an…”
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Regulatory elements from the related spec genes of Strongylocentrotus purpuratus yield different spatial patterns with a lacZ reporter gene by Gan, Lin, Wessel, Gary M., Klein, William H.

“…The Spec1 and Spec2 genes of Strongylocentrotus purpuratus are closely associated with the differentiation of aboral ectoderm. To examine cis-regulatory…”
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Cortical granule-specific components are present within oocytes and accessory cells during sea urchin oogenesis by Wessel, GM

“…The coordinate expression of cortical granule-specific components in sea urchin oogenesis was studied using antibody probes. The components used to generate…”
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Intercellular Recognition: Quantitation of Initial Binding Events by McClay, David R., Wessel, Gary M., Marchase, Richard B.

“…The hypothesis that intercellular adhesion can be subdivided into two separable phenomena--an initial recognition event and a subsequent stabilization--is…”
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Membrane Trafficking Machinery Components Associated with the Mammalian Acrosome during Spermiogenesis by Ramalho-Santos, João, Moreno, Ricardo D., Wessel, Gary M., Chan, Edward K.L., Schatten, Gerald

“…Active trafficking from the Golgi apparatus is involved in acrosome formation, both by delivering acrosomal contents to the nascent secretory vesicle and by…”
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Gastrulation in the sea urchin is accompanied by the accumulation of an endoderm-specific mRNA by Wessel, Gary M., Goldberg, Leah, Lennarz, William J., Klein, William H.

“…Spatial diversification of the endoderm during gastrulation in the sea urchin Lytechinus variegatus was examined with an endoderm-specific cDNA clone. This…”
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Two embryonic, tissue-specific molecules identified by a double-label immunofluorescence technique for monoclonal antibodies by Wessel, GM, McClay, DR

“…We identify two tissue-specific molecules in the sea urchin embryo by an immunofluorescence technique capable of co-localizing monoclonal antibodies on the…”
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Selective transport and packaging of the major yolk protein in the sea urchin by Brooks, Jacqueline M, Wessel, Gary M

“…The major yolk protein of sea urchins is an iron-binding, transferrin-like molecule that is made in the adult gut. Its final destination though is the…”
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Sequential expression of germ-layer specific molecules in the sea urchin embryo by Wessel, Gary M., McClay, David R.

“…Described are two germ-layer specific molecules that appear coincident with the formation of two germ layer cell lineages in the sea urchin embryo. Meso1 is a…”
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SNAREs in Mammalian Sperm: Possible Implications for Fertilization by Ramalho-Santos, João, Moreno, Ricardo D., Sutovsky, Peter, Chan, Anthony Wing-Sang, Hewitson, Laura, Wessel, Gary M., Simerly, Calvin R., Schatten, Gerald

“…Soluble N-ethylmalameide-sensitive factor attachment protein receptor (SNARE) proteins are present in mammalian sperm and could be involved in critical…”
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Cyclin B synthesis is required for sea urchin oocyte maturation by Voronina, Ekaterina, Marzluff, William F, Wessel, Gary M

“…Sea urchins are members of a limited group of animals in which meiotic maturation of oocytes is completed prior to fertilization. This is different from…”
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Ontogeny of the basal lamina in the sea urchin embryo by Wessel, Gary M., Marchase, Richard B., McClay, David R.

“…The patterns of expression for several extracellular matrix components during development of the sea urchin embryo are described. An immunofluorescence assay…”
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Transient, Localized Accumulation of α-Spectrin during Sea Urchin Morphogenesis by Wessel, Gary M., Chen, Siming W.

“…The mRNA and protein of α-spectrin in the sea urchin embryo is shown here to be transiently overexpressed in cells initiating certain morphogenetic changes…”
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