Search Results - "WENXUE TANG"

Myeloid-derived suppressor cells-new and exciting players in lung cancer by Yang, Zhenzhen, Guo, Jiacheng, Weng, Lanling, Tang, Wenxue, Jin, Shuiling, Ma, Wang

“…Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late diagnosis and poor outcomes. As has been found for other types of…”
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Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma by Cao, Wei, Lee, Hayan, Wu, Wei, Zaman, Aubhishek, McCorkle, Sean, Yan, Ming, Chen, Justin, Xing, Qinghe, Sinnott-Armstrong, Nasa, Xu, Hongen, Sailani, M. Reza, Tang, Wenxue, Cui, Yuanbo, liu, Jia, Guan, Hongyan, Lv, Pengju, Sun, Xiaoyan, Sun, Lei, Han, Pengli, Lou, Yanan, Chang, Jing, Wang, Jinwu, Gao, Yuchi, Guo, Jiancheng, Schenk, Gundolf, Shain, Alan Hunter, Biddle, Fred G., Collisson, Eric, Snyder, Michael, Bivona, Trever G.

“…Epigenetic landscapes can shape physiologic and disease phenotypes. We used integrative, high resolution multi-omics methods to delineate the methylome…”
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Assessing Community-Level Livability Using Combined Remote Sensing and Internet-Based Big Geospatial Data by Zhu, Likai, Guo, Yuanyuan, Zhang, Chi, Meng, Jijun, Ju, Lei, Zhang, Yuansuo, Tang, Wenxue

“…With rapid urbanization, retrieving livability information of human settlements in time is essential for urban planning and governance. However, livability…”
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Timed conditional null of connexin26 in mice reveals temporary requirements of connexin26 in key cochlear developmental events before the onset of hearing by Chang, Qing, Tang, Wenxue, Kim, Yeunjung, Lin, Xi

“…Abstract Mutations in the Gjb2 gene, which encodes a gap junction protein connexin26 (Cx26), are the most prevalent form of hereditary deafness in humans and…”
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Dynamics of binding ability prediction between spike protein and human ACE2 reveals the adaptive strategy of SARS-CoV-2 in humans by Xue, Xia, Shi, Jianxiang, Xu, Hongen, Qin, Yaping, Yang, Zengguang, Feng, Shuaisheng, Liu, Danhua, Jian, Liguo, Hua, Linlin, Wang, Yaohe, Zhang, Qi, Huang, Xueyong, Zhang, Xiaoju, Li, Xinxin, Chen, Chunguang, Guo, Jiancheng, Tang, Wenxue, Liu, Jianbo

“…SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel coronavirus causing the COVID-19 pandemic in 2020. High adaptive plasticity on the…”
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Superoxide dismutase@zeolite Imidazolate Framework-8 Attenuates Noise-Induced Hearing Loss in Rats by Zhang, Yan, Li, Qing, Han, Chengzhou, Geng, Fang, Zhang, Sen, Qu, Yan, Tang, Wenxue

“…Reactive oxygen species (ROS) and inflammation have been considered major contributors to noise-induced hearing loss (NIHL) that constituted a public health…”
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A novel splicing variant in the TMC1 gene causes non-syndromic hearing loss in a Chinese family by Zeng, Beiping, Xu, Hongen, Tian, Yongan, Lin, Qianyu, Feng, Haifeng, Zhang, Zhifeng, Li, Siqi, Tang, Wenxue

“…The parents were non-consanguineous and the proband had no history of noise exposure, ototoxic drug usage, external ear trauma, birth injury, hypoxia or…”
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Pretreatment with geniposide mitigates myocardial ischemia/reperfusion injury by modulating inflammatory response through TLR4/NF-κB pathway by Yao, Yanmei, Lin, Leqing, Tang, Wenxue, Shen, Yueliang, Chen, Fayu, Li, Ning, Wang, Baiyong

“…Geniposide (GEN), a medical herb, is known for its therapeutic applications in cardiovascular diseases, though its efficacy in treating myocardial…”
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Near‐infrared laser‐activated aggregation‐induced emission nanoparticles boost tumor carbonyl stress and immunotherapy of breast cancer by Pan, You, Suo, Meng, Huang, Qinqin, Lyu, Meng, Jiang, Yi, Wang, Shile, Tang, Wenxue, Ning, Shipeng, Zhang, Tianfu

“…The induction of tumor carbonyl stress is reported to efficiently revert immune suppression in the tumor microenvironment and enhance cancer immunotherapy…”
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Novel likely pathogenic variant in the EYA1 gene causing Branchio oto renal syndrome and the exploration of pathogenic mechanisms by Zhang, Hui, Gao, Jian, Wang, Hanjun, Liu, Mengli, Lu, Shuangshuang, Xu, Hongen, Tang, Wenxue, Zheng, Guoxi

“…Branchio-oto-renal syndrome (BOR, OMIM#113,650) is a rare autosomal dominant disorder that presents with a variety of symptoms, including hearing loss…”
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Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities by Lin, Xi, Tang, Wenxue, Ahmad, Shoeb, Lu, Jingqiao, Colby, Candice C., Zhu, Jason, Yu, Qing

“…The goal of sequencing the entire human genome for $1000 is almost in sight. However, the total costs including DNA sequencing, data management, and analysis…”
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Novel compound heterozygous pathogenic variants in the SLC3A1 gene in a Chinese family with cystinuria by Liu, Danhua, Zhao, Yongli, Xue, Xia, Hou, Xinyue, Xu, Hongen, Zhao, Xinghua, Tian, Yongan, Tang, Wenxue, Guo, Jiancheng, Xu, Changbao

“…Cystinuria is an autosomal recessive disorder characterized by a cystine transport deficiency in the renal tubules due to mutations in two genes: SLC3A1 and…”
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Genetic and Phenotypic Variability in Chinese Patients With Branchio-Oto-Renal or Branchio-Oto Syndrome by Feng, Haifeng, Xu, Hongen, Chen, Bei, Sun, Shuping, Zhai, Rongqun, Zeng, Beiping, Tang, Wenxue, Lu, Wei

“…Background: Branchio-oto-renal syndrome (BOR) and branchio-oto syndrome (BOS) are rare autosomal dominant disorders defined by varying combinations of…”
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Roles of HMGB1 in regulating myeloid-derived suppressor cells in the tumor microenvironment by Jin, Shuiling, Yang, Zhenzhen, Hao, Xin, Tang, Wenxue, Ma, Wang, Zong, Hong

“…Myeloid-derived suppressor cells (MDSCs) are notable contributors to the immunosuppressive tumor microenvironment (TME) and are closely associated with tumor…”
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Phenotypic variability in two female siblings with oocyte maturation arrest due to a TUBB8 variant by Dou, Qian, Xu, HongEn, Ma, LiYing, Tan, Li, Tang, WenXue

“…Tubulin beta-8 ( TUBB8 ) is expressed exclusively in the oocyte and early embryo, encoding a beta-tubulin polypeptide that participates in the assembly of…”
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Detection and clinical significance of circulating tumor cells in colorectal cancer by Jiang, Miao, Jin, Shuiling, Han, Jinming, Li, Tong, Shi, Jianxiang, Zhong, Qian, Li, Wen, Tang, Wenxue, Huang, Qinqin, Zong, Hong

“…Histopathological examination (biopsy) is the “gold standard” for the diagnosis of colorectal cancer (CRC). However, biopsy is an invasive method, and due to…”
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Connexin30 null and conditional connexin26 null mice display distinct pattern and time course of cellular degeneration in the cochlea by Sun, Yu, Tang, Wenxue, Chang, Qing, Wang, Yunfeng, Kong, Weijia, Lin, Xi

“…Mutations in connexin26 (Cx26) and Cx30 are the most common cause of nonsyndromic inherited deafness in humans. To understand the underlying molecular…”
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Hydrogel co-loading SO2 prodrug and FeGA nanoparticles for enhancing chemodynamic therapy by photothermal-triggered SO2 gas therapy by Huang, Qinqin, Lyu, Meng, Tang, Wenxue, Qi, Pengyuan, Hu, Hongzhi

“…Chemodynamic therapy (CDT) is an effective anti-tumor method, while CDT alone cannot achieve a good therapeutic effect. Moreover, the overexpression of…”
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Involvement of Glutathione Depletion in Selective Cytotoxicity of Oridonin to p53-Mutant Esophageal Squamous Carcinoma Cells by Li, Yinchao, Li, Nana, Shi, Jianxiang, Ahmed, Tanzeel, Liu, Hongmin, Guo, Jiancheng, Tang, Wenxue, Guo, Yongjun, Zhang, Qi

“…Oridonin, a diterpenoid compound isolated from traditional Chinese medicine Rabdosia rubescens, has shown antitumor effects to esophageal cancer. However, its…”
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Establishment of an induced pluripotent stem cell line (ZZUPMCi001-A) derived from peripheral blood mononuclear cells in a patient with type 1 Waardenburg syndrome by Wang, Xiaoxuan, Zhang, Sen, Hu, Sang, Xu, Hongen, Zhang, Qi, Tang, Wenxue

“…Waardenburg syndrome type I (WS1) is a human autosomal dominant genetic disease characterized by sensorineural hearing loss, pigmentary abnormalities, and…”
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