Search Results - "WENNING, Gregor"
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Multiple-System Atrophy
Published in The New England journal of medicine (15-01-2015)“…Multiple-system atrophy is a neurodegenerative disease characterized by progressive autonomic failure, parkinsonism, and cerebellar and pyramidal tract…”
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Multiple system atrophy: insights into a rare and debilitating movement disorder
Published in Nature reviews. Neurology (01-04-2017)“…Key Points Multiple system atrophy (MSA) is a sporadic and rare neurodegenerative movement disorder with an estimated annual incidence of 0.6 per 100,000 (…”
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Glia and alpha-synuclein in neurodegeneration: A complex interaction
Published in Neurobiology of disease (01-01-2016)“…Abstract α-Synucleinopathies (ASP) comprise adult-onset, progressive neurodegenerative disorders such as Parkinson's disease (PD), dementia with Lewy bodies…”
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Iron in Neurodegeneration - Cause or Consequence?
Published in Frontiers in neuroscience (01-03-2019)“…Iron dyshomeostasis can cause neuronal damage to iron-sensitive brain regions. Neurodegeneration with brain iron accumulation reflects a group of disorders…”
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Multiple system atrophy: at the crossroads of cellular, molecular and genetic mechanisms
Published in Nature reviews. Neuroscience (01-06-2023)“…Multiple system atrophy (MSA) is a rare oligodendroglial α-synucleinopathy characterized by neurodegeneration in striatonigral and olivopontocerebellar regions…”
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Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
Published in Glia (01-03-2013)“…Alpha‐synucleinopathies (ASP) are neurodegenerative disorders, characterized by accumulation of misfolded α‐synuclein, selective neuronal loss, and extensive…”
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The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy
Published in Movement disorders (01-06-2022)“…ABSTRACT Background The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for…”
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Autonomic failure: a neglected presentation of Parkinson's disease
Published in Lancet neurology (01-10-2021)Get full text
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Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
Published in The American journal of pathology (01-08-2011)“…Toll-like receptors (TLRs) mediate innate immunity, and their dysregulation may play a role in α-synucleinopathies, such as Parkinson's disease or multiple…”
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Current experimental disease-modifying therapeutics for multiple system atrophy
Published in Journal of Neural Transmission (01-10-2021)“…Multiple system atrophy (MSA) is a challenging neurodegenerative disorder with a difficult and often inaccurate early diagnosis, still lacking effective…”
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Diffusion-weighted MRI distinguishes Parkinson disease from the parkinsonian variant of multiple system atrophy: A systematic review and meta-analysis
Published in PloS one (29-12-2017)“…Putaminal diffusivity in brain magnetic resonance diffusion-weighted imaging (DWI) is increased in patients with the parkinsonian variant of multiple system…”
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Parkinsonism and dysautonomia: Multiple system atrophy?
Published in Parkinsonism & related disorders (01-08-2020)Get full text
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Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy
Published in Movement disorders (01-02-2019)“…ABSTRACT Background MSA is a fatal neurodegenerative disease characterized by autonomic failure and severe motor impairment. Its main pathological hallmark is…”
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Electrodiagnostic assessment of the autonomic nervous system: A consensus statement endorsed by the American Autonomic Society, American Academy of Neurology, and the International Federation of Clinical Neurophysiology
Published in Clinical neurophysiology (01-02-2021)“…•Sensitive, validated, noninvasive electrodiagnostic tests of autonomic function have been developed.•An international expert panel provides evidence-based…”
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Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria
Published in Movement disorders (01-06-2017)“…ABSTRACT Background: PSP is a neuropathologically defined disease entity. Clinical diagnostic criteria, published in 1996 by the National Institute of…”
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Kurt Jellinger, Doyen of international neuropathology
Published in Journal of Neural Transmission (01-10-2021)Get full text
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Gender differences in clinical, laboratory and polysomnographic features of restless legs syndrome
Published in Journal of sleep research (01-06-2020)“…Summary Restless legs syndrome is a common neurological disorder with a clear female predominance. This study aims to evaluate gender differences in clinical,…”
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Which Autonomic Features Distinguish Multiple System Atrophy and When
Published in Movement disorders (01-05-2020)Get full text
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Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
Published in Acta neuropathologica (01-06-2011)“…Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA) are adult onset neurodegenerative disorders characterised by…”
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Milestones in atypical and secondary Parkinsonisms
Published in Movement disorders (01-05-2011)“…During the last decades, atypical parkinsonian disorders such as multiple system atrophy, dementia with Lewy bodies, progressive supranuclear palsy, and…”
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