Search Results - "WENK, M. L"

Gender differences in serotype 2 adeno-associated virus biodistribution after administration to rodent salivary glands by Voutetakis, A, Zheng, C, Wang, J, Goldsmith, C M, Afione, S, Chiorini, J A, Wenk, M L, Vallant, M, Irwin, R D, Baum, B J

“…Salivary glands (SGs) have proven useful targets for clinical applications of gene therapeutics. In this toxicology and biodistribution study, which conforms…”
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Toxicologic evaluation of flavor ingredients added to cigarette tobacco: skin painting bioassay of cigarette smoke condensate in SENCAR mice by Gaworski, C.L., Heck, J.D., Bennett, M.B., Wenk, M.L.

“…Four comparative two-stage SENCAR mouse skin painting bioassays were conducted with cigarette smoke condensate (CSC) preparations to evaluate the effect of…”
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Activated neu Oncogene Sequences in Primary Tumors of the Peripheral Nervous System Induced in Rats by Transplacental Exposure to Ethylnitrosourea by Perantoni, Alan O., Rice, Jerry M., Reed, Carl D., Watatani, Masahiro, Wenk, Martin L.

“…Neurogenic tumors were selectively induced in high incidence in F344 rats by a single transplacental exposure to the direct-acting alkylating agent…”
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The Hepatocarcinogen Methapyrilene but Not the Analog Pyrilamine Induces Sustained Hepatocellular Replication and Protein Alterations in F344 Rats in a 13-Week Feed Study by Cunningham, M.L., Pippin, L.L., Anderson, N.L., Wenk, M.L.

“…Methapyrilene (MPH) was a widely used antihistamine until it was found to produce hepatocellular carcinoma and cholangiocarcinoma in Fischer 344 rats. The…”
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Activated K-ras and N-ras oncogenes in primary renal mesenchymal tumors induced in F344 rats by methyl(methoxymethyl)nitrosamine by SUKUMAR, S, PERANTONI, A, REED, C, RICE, J. M, WENK, M. L

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cadmium carcinogenesis in male wistar [Crl:(WI)BR] rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site by WAALKES, M. P, REHM, S, RIGGS, C. W, BARE, R. M, DEVOR, D. E, POIRIER, L. A, WENK, M. L, HENNEMAN, J. R, BALASCHAK, M. S

“…Carcinogenic dose-response effects of CdCl2 in male Wistar [Crl:(WI)BR] rats were studied over a 2-year period. Groups of rats received a single s.c. injection…”
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Glycine modulates the toxicity of benzyl acetate in F344 rats by Abdo, K M, Wenk, M L, Harry, G J, Mahler, J, Goehl, T J, Irwin, R D

“…The influence of supplemental glycine on benzyl acetate (BA; a compound metabolized via the hippurate pathway)-induced toxicity was investigated. Groups of…”
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Toxicity of 3,3′,4,4′-Tetrachloroazobenzene in Rats and Mice by van Birgelen, Angélique P.J.M., Hébert, Charles D., Wenk, Martin L., Grimes, Linda K., Chapin, Robert E., Mahler, Joel, Travlos, Greg S., Bucher, John R.

“…The toxicity of 3,3′,4,4′-tetrachloroazobenzene (TCAB) was evaluated in 13-week gavage studies in male and female F344/N rats and B6C3F1mice. In addition to…”
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Toxicity of 3,3′,4,4′-Tetrachloroazoxybenzene in Rats and Mice by van Birgelen, Angélique P.J.M., Hébert, Charles D., Wenk, Martin L., Grimes, Linda K., Chapin, Robert E., Travlos, Greg S., Mahler, Joel, Bucher, John R.

“…The toxicity of 3,3′,4,4′-tetrachloroazoxybenzene (TCAOB) was evaluated in 13-week gavage studies in male and female F344/N rats and B6C3F1mice. In addition to…”
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Plasmid DNA malaria vaccine: tissue distribution and safety studies in mice and rabbits by Parker, S E, Borellini, F, Wenk, M L, Hobart, P, Hoffman, S L, Hedstrom, R, Le, T, Norman, J A

“…To evaluate the safety of a plasmid DNA vaccine, tissue distribution studies in mice and safety studies in mice and rabbits were conducted with VCL-2510, a…”
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Infrequent activation of K-ras, H-ras, and other oncogenes in hepatocellular neoplasms initiated by methyl(acetoxymethyl)nitrosamine, a methylating agent, and promoted by phenobarbital in F344 rats by WATATANI, M, PERANTONI, A. O, REED, C. D, ENOMOTO, T, WENK, M. L, RICE, J. M

“…Fischer 344/Ncr rats of both sexes were subjected to partial hepatectomy and then initiated 21-24 h later by a single injection of…”
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Preventive and enhancing effects of retinoids on the development of naturally occurring tumors of skin, prostate gland, and endocrine pancreas in aged male ACI/segHapBR rats by Ohshima, M, Ward, J M, Wenk, M L

“…The effects of dietary retinoids on the development of naturally occurring tumors in retired breeder male ACI/segHapBR rats were investigated. Groups of rats…”
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Effects of calcium and magnesium acetates on the carcinogenicity of cadmium chloride in Wistar rats by POIRIER, L. A, KASPRZAK, K. S, HOOVER, K. L, WENK, M. L

“…The effects of calcium and magnesium acetates on the formation of injection site and testicular tumors in male Wistar rats over 2 years following s.c…”
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Proliferation of carcinogen-damaged hepatocytes during cell-cycle-dependent initiation of hepatocarcinogenesis in the rat by Kaufmann, W K, Rice, J M, MacKenzie, S A, Smith, G J, Wenk, M L, Devor, D, Qaqish, B F, Kaufman, D G

“…Hepatocyte proliferation and damage to DNA were characterized during the initiation phase of carcinogenesis in livers of rats that had received a single…”
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Cell cycle-dependent initiation of hepatocarcinogenesis in rats by methyl(acetoxymethyl)nitrosamine by KAUFMANN, W. K, RICE, J. M, WENK, M. L, DEVOR, D, KAUFMAN, D. G

“…Hepatocyte sensitivity to initiation of carcinogenesis was studied as a function of the cell cycle phase in which damage was incurred. Hepatocytes were…”
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Anomalous growth of rat incisor teeth during chronic intermittent vitamin A deficiency by McDowell, E M, Shores, R L, Spangler, E F, Wenk, M L, De Luca, L M

“…Rapid, synchronous and repeating cycles of marginal retinoic acid sufficiency and deficiency were produced in rats by following an established protocol. During…”
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Ethionine carcinogenesis in CD-1, BALB/c and C3H mice by Hoover, K L, Hyde, C L, Wenk, M L, Poirier, L A

“…In two separate in vivo studies, ethionine was evaluated for carcinogenic activity in mice. In the first study, DL-ethionine was fed in a chow diet at 0…”
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Effects of short-term exposure to the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on skin carcinogenesis in SENCAR mice by Diwan, B A, Ward, J M, Henneman, J, Wenk, M L

“…Skin tumor promotion after a short-term exposure to 12-O-tetradecanoylphorbol-13-acetate (TPA) was studied in female SENCAR mice. Mice were dosed once by the…”
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Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters by Hennings, Henry, Shores, Robert, Wenk, Martin L, Spangler, Edwin F, Tarone, Robert, Yuspa, Stuart H

“…Multi-stage carcinogenesis (initiation-promotion) was first demonstrated in mouse skin. The first stage, initiation, is accomplished by a low dose of…”
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Cadmium carcinogenesis in male Wistar [Crl:(WI)BR] rats: dose-response analysis of effects of zinc on tumor induction in the prostate, in the testes, and at the injection site by Waalkes, M P, Rehm, S, Riggs, C W, Bare, R M, Devor, D E, Poirier, L A, Wenk, M L, Henneman, J R

“…The ability of zinc acetate to modify the carcinogenic effects of CdCl2 in male Wistar [Crl:(WI)BR] rats was studied over a 2-year period. Groups of rats…”
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