Search Results - "WENDLAND, Michael F"

miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes by Qian, Li, Van Laake, Linda W, Huang, Yu, Liu, Siyuan, Wendland, Michael F, Srivastava, Deepak

“…Acute myocardial infarction (MI) involves necrotic and apoptotic loss of cardiomyocytes. One strategy to salvage ischemic cardiomyocytes is to modulate gene…”
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Magnetic Particle Imaging for Highly Sensitive, Quantitative, and Safe in Vivo Gut Bleed Detection in a Murine Model by Yu, Elaine Y, Chandrasekharan, Prashant, Berzon, Ran, Tay, Zhi Wei, Zhou, Xinyi Y, Khandhar, Amit P, Ferguson, R. Matthew, Kemp, Scott J, Zheng, Bo, Goodwill, Patrick W, Wendland, Michael F, Krishnan, Kannan M, Behr, Spencer, Carter, Jonathan, Conolly, Steven M

“…Gastrointestinal (GI) bleeding causes more than 300 000 hospitalizations per year in the United States. Imaging plays a crucial role in accurately locating the…”
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Microglial cells contribute to endogenous brain defenses after acute neonatal focal stroke by Faustino, Joel V, Wang, Xia, Johnson, Cali E, Klibanov, Alexander, Derugin, Nikita, Wendland, Michael F, Vexler, Zinaida S

“…Macrophages are viewed as amplifiers of ischemic brain injury, but the origin of injury-producing macrophages is poorly defined. The role of resident brain…”
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Mesenchymal stem cells attenuate MRI‐identifiable injury, protect white matter, and improve long‐term functional outcomes after neonatal focal stroke in rats by van Velthoven, Cindy T., Dzietko, Mark, Wendland, Michael F., Derugin, Nikita, Faustino, Joel, Heijnen, Cobi J., Ferriero, Donna M., Vexler, Zinaida S.

“…Cell therapy has emerged as a potential treatment for many neurodegenerative diseases including stroke and neonatal ischemic brain injury. Delayed intranasal…”
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Neonatal cerebral hypoxia-ischemia impairs plasticity in rat visual cortex by Failor, Samuel, Nguyen, Vien, Darcy, Daniel P, Cang, Jianhua, Wendland, Michael F, Stryker, Michael P, McQuillen, Patrick S

“…Ocular dominance plasticity (ODP) following monocular deprivation (MD) is a model of activity-dependent neural plasticity that is restricted to an early…”
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T1 and T2 relaxivity of intracellular and extracellular USPIO at 1.5T and 3T clinical MR scanning by Simon, Gerhard H, Bauer, Jan, Saborovski, Olaf, Fu, Yanjun, Corot, Claire, Wendland, Michael F, Daldrup-Link, Heike E

“…In this study we evaluated the effects of intracellular compartmentalization of the ultrasmall superparamagnetic iron oxide (USPIO) ferumoxtran-10 on its…”
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Minocycline confers early but transient protection in the immature brain following focal cerebral ischemia-reperfusion by Fox, Christine, Dingman, Andra, Derugin, Nikita, Wendland, Michael F, Manabat, Catherine, Ji, Shaoquan, Ferriero, Donna M, Vexler, Zinaida S

“…The incidence of neonatal stroke is high and currently there are no strategies to protect the neonatal brain from stroke or reduce the sequelae. Agents capable…”
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Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain by Saito, Ryuta, Krauze, Michal T., Bringas, John R., Noble, Charles, McKnight, Tracy R., Jackson, Pamela, Wendland, Michael F., Mamot, Christoph, Drummond, Daryl C., Kirpotin, Dimitri B., Hong, Keelung, Berger, Mitchel S., Park, John W., Bankiewicz, Krystof S.

“…Drug delivery to brain tumors has long posed a major challenge. Convection-enhanced delivery (CED) has been developed as a drug delivery strategy to overcome…”
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Direct Quantification of Intervertebral Disc Water Content Using MRI by Yang, Bo, Wendland, Michael F., O'Connell, Grace D.

“…Background Water content is a key parameter for simulating tissue swelling and nutrient diffusion. Accurately measuring water content throughout the…”
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Noninvasively differentiating acute and chronic nephropathies via multiparametric urea‐CEST, nuclear Overhauser enhancement‐CEST, and quantitative magnetization transfer MRI by Shin, Soo Hyun, Wendland, Michael F., Wang, Jingshen, Velasquez, Mark, Vandsburger, Moriel H.

“…Purpose Standardized blood tests often lack adequate sensitivity and specificity to capture the gradual progression of renal injuries. We suggest a…”
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Delayed urea differential enhancement CEST (dudeCEST)‐MRI with T1 correction for monitoring renal urea handling by Shin, Soo Hyun, Wendland, Michael F., Vandsburger, Moriel H.

“…Purpose We demonstrate a method of delayed urea differential enhancement CEST for probing urea recycling action of the kidney using expanded multi‐pool…”
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Delayed urea differential enhancement CEST (dudeCEST)-MRI with T 1 correction for monitoring renal urea handling by Shin, Soo Hyun, Wendland, Michael F, Vandsburger, Moriel H

“…We demonstrate a method of delayed urea differential enhancement CEST for probing urea recycling action of the kidney using expanded multi-pool Lorentzian…”
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Evaluation of a Novel Macromolecular Cascade-Polymer Contrast Medium for Dynamic Contrast-Enhanced MRI Monitoring of Antiangiogenic Bevacizumab Therapy in a Human Melanoma Model by Cyran, Clemens C., MD, Fu, Yanjun, PhD, Rogut, Victor, MD, Chaopathomkul, Bundit, MD, Wendland, Michael F., PhD, Shames, David M., MD, Brasch, Robert C., MD

“…Rationale and Objectives To assess the applicability of a novel macromolecular polyethylene glycol (PEG)-core gadolinium contrast agent for monitoring early…”
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New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues by Cyran, Clemens C., Fu, Yanjun, Raatschen, Hans-Juergen, Rogut, Victor, Chaopathomkul, Bundit, Shames, David M., Wendland, Michael F., Yeh, Benjamin M., Brasch, Robert C.

“…Purpose To compare three new macromolecular polyethylene glycol (PEG) ‐core dendrimeric gadolinium(Gd)‐based MRI contrast agents for their applicability in…”
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Early Diffusion-Weighted MRI as a Predictor of Caspase-3 Activation After Hypoxic-Ischemic Insult in Neonatal Rodents by WENDLAND, Michael F, FAUSTINO, Joel, WEST, Tim, MANABAT, Catherine, HOLTZMAN, David M, VEXLER, Zinaida S

“…Neonatal encephalopathy in human babies is a serious condition associated with permanent neurological deficits. Diffusion-weighted MRI (DWI) is increasingly…”
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MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles by Daldrup-Link, Heike E, Golovko, Daniel, Ruffell, Brian, Denardo, David G, Castaneda, Rosalinda, Ansari, Celina, Rao, Jianghong, Tikhomirov, Grigory A, Wendland, Michael F, Corot, Claire, Coussens, Lisa M

“…The presence of tumor-associated macrophages (TAM) in breast cancer correlates strongly with poor outcome. The purpose of this study was to develop a…”
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Blood-brain barrier permeability is increased after acute adult stroke but not neonatal stroke in the rat by Fernández-López, David, Faustino, Joel, Daneman, Richard, Zhou, Lu, Lee, Sarah Y, Derugin, Nikita, Wendland, Michael F, Vexler, Zinaida S

“…The immaturity of the CNS at birth greatly affects injury after stroke but the contribution of the blood-brain barrier (BBB) to the differential response to…”
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Cascade Polymeric MRI Contrast Media Derived from Poly(ethylene glycol) Cores:  Initial Syntheses and Characterizations by Fu, Yanjun, Raatschen, Hans-Juergen, Nitecki, Danute E, Wendland, Michael F, Novikov, Viktor, Fournier, Laure S, Cyran, Clemens, Rogut, Victor, Shames, David M, Brasch, Robert C

“…Diagnostic contrast media for magnetic resonance imaging (MRI) are often applied to enhance the signal of blood allowing for quantitative definition of…”
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Noninvasive imaging of renal urea handling by CEST‐MRI by Shin, Soo Hyun, Wendland, Michael F., Zhang, Brandon, Tran, An, Tang, Albert, Vandsburger, Moriel H.

“…Purpose Renal function is characterized by concentration of urea for removal in urine. We tested urea as a CEST‐MRI contrast agent for measurement of the…”
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Correlative dynamic contrast MRI and microscopic assessments of tumor vascularity in RIP-tag2 transgenic mice by Sennino, Barbara, Raatschen, Hans-Juergen, Wendland, Michael F., Fu, Yanjun, You, Weon-Kyoo, Shames, David M., McDonald, Donald M., Brasch, Robert C.

“…The purpose of this study was to define the feasibility of dynamic contrast‐enhanced magnetic resonance imaging (MRI) to estimate the vascular density and…”
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