Search Results - "WELSH, Ken I"

The molecular classification of the clinical manifestations of Crohn's disease by Ahmad, Tariq, Armuzzi, Alessandro, Bunce, Mike, Mulcahy-Hawes, Kim, Marshall, Sara E., Orchard, Timothy R., Crawshaw, Jonathan, Large, Oliver, De Silva, Arjuna, Cook, Julia T., Barnardo, Martin, Cullen, Sue, Welsh, Ken I., Jewell, Derek P.

“…Crohn's disease is a common inflammatory disorder of the gut characterized by variation in both location and behavior. Chromosome 16 and the HLA region on…”
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Clinical Pharmacology and Pharmacotherapy of Opioid Switching in Cancer Patients by Ross, Joy R., Riley, Julia, Quigley, Columba, Welsh, Ken I.

“…Learning Objectives After completing this course, the reader will be able to: Describe some of the underlying mechanisms that contribute to why patients show…”
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Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC by Ahmad, Tariq, Neville, Matt, Marshall, Sara E., Armuzzi, Alessandro, Mulcahy-Hawes, Kim, Crawshaw, Jonathan, Sato, Hiroe, Ling, Khoon-Lin, Barnardo, Martin, Goldthorpe, Sue, Walton, Robert, Bunce, Mike, Jewell, Derek P., Welsh, Ken I.

“…Detailed knowledge of linkage disequilibrium (LD) is regarded as a prerequisite for population-based disease gene mapping. Variable patterns across the human…”
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Donor and recipient CMV serostatus and antigenemia after renal transplantation: An analysis of 486 patients by Hughes, David, Hafferty, John, Fulton, Lee, Friend, Peter, Devaney, Andrea, Loke, Justin, Welsh, Ken I, Handa, Ashok, Klenerman, Paul

“…Abstract Background Cytomegalovirus infection in renal transplant recipients is a major clinical problem, with both short and long term sequelae. Infection can…”
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Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease by Satsangi, J, Welsh, K I, Bunce, M, Julier, C, Farrant, J M, Bell, J I, Jewell, D P

“…Despite strong evidence implicating immune dysfunction and genetic predisposition in the pathogenesis of the chronic inflammatory bowel diseases Crohn's…”
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A Functional Polymorphism of the Stromelysin Gene (MMP-3) Influences Susceptibility to Primary Sclerosing Cholangitis by Satsangi, Jack, Chapman, Roger W.G., Haldar, Neil, Donaldson, Peter, Mitchell, Stephen, Simmons, Jon, Norris, Suzanne, Marshall, Sara E., Bell, John I., Jewell, Derek P., Welsh, Ken I.

“…Background & Aims: We have investigated the influence of a biallelic polymorphism of the promoter region of stromelysin (matrix metalloproteinase 3) on…”
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Donor cytokine genotype influences the development of acute rejection after renal transplantation by MARSHALL, Sara E, MCLAREN, Andrew J, MCKINNEY, Eoin F, BIRD, Tom G, HALDAR, Neil A, BUNCE, Mike, MORRIS, Peter J, WELSH, Ken I

“…Acute allograft rejection remains an important cause of morbidity after kidney transplantation, and has been shown to be a crucial determinant of long-term…”
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The impact of recipient cytokine genotype on acute rejection after renal transplantation by MARSHALL, Sara E, MCLAREN, Andrew J, HALDAR, Neil A, BUNCE, Mike, MORRIS, Peter J, WELSH, Ken I

“…Acute allograft rejection remains an important cause of morbidity after kidney transplantation, and has been shown to be a crucial determinant of long-term…”
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The impact of thiopurine S-methyltransferase polymorphisms on azathioprine dose 1 year after renal transplantation by Fabre, Margarete A, Jones, Des C, Bunce, Mike, Morris, Peter J, Friend, Peter J, Welsh, Ken I, Marshall, Sara E

“…Azathioprine metabolism is influenced by activity of the enzyme thiopurine S-methyltransferase (TPMT), which varies markedly between individuals. In this study…”
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Oxygen free radical scavenger enzyme polymorphisms in systemic sclerosis by Tikly, Mohammed, Marshall, Sara E, Haldar, Neil A, Gulumian, Mary, Wordsworth, Paul, Welsh, Ken I

“…We performed a case–control study of polymorphisms of glutathione S-transferase (GST) isoenzymes and manganese superoxide dismutase (MnSOD) in black South…”
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The Clara Cell10 Adenine38Guanine Polymorphism and Sarcoidosis Susceptibility in Dutch and Japanese Subjects by Janssen, Rob, Sato, Hiroe, Grutters, Jan C, Ruven, Henk J. T, du Bois, Ron M, Matsuura, Ryosuke, Yamazaki, Masao, Kunimaru, Shigeki, Izumi, Takateru, Welsh, Ken I, Nagai, Sonoko, van den Bosch, Jules M. M

“…CC10 (CC16, uteroglobin) is a pulmonary protein postulated to play a counter regulatory role in sarcoidosis pathogenesis. The adenine38guanine (A38G)…”
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Analysis of KL-6 and SP-D as disease markers in bird fancier's lung by Janssen, Rob, Grutters, Jan C, Sato, Hiroe, van Velzen-Blad, Heleen, Zanen, Pieter, Kohno, Nobuoki, Welsh, Ken I, du Bois, Roland M, van den Bosch, Jules M M

“…KL-6 and SP-D are potential serum markers in interstitial lung diseases. Their discriminative value, and ability to reflect pulmonary disease activity and…”
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Differential immunogenicity of HLA mismatches: HLA-A2 versus HLA-A28 by DANKERS, Marlies K. A, ROELEN, Dave L, VAN DER MEER-PAINS, Ellen M. W, DE LANGE, Peter, KORFAGE, Nelleke, SMITS, Jacqueline M. A, PERSIJN, Guido G, WELSH, Ken I, DOXIADIS, Ilias I. N, CLAAS, Frans H. J

“…The immunogenicity of human leukocyte antigen (HLA)-A2 versus HLA-A28 was analyzed by antibody production, cytotoxic T-lymphocyte (CTL) induction, and graft…”
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The impact of endothelial nitric oxide synthase polymorphisms on long-term renal allograft outcome by Shenker, Natalie S, Haldar, Neil A, Reilly, John-Joe, Bunce, Mike, Welsh, Ken I, Marshall, Sara E

“…A major manifestation of chronic allograft failure (CAF) is the accelerated onset of atherosclerotic lesions within the graft. Polymorphisms in the endothelial…”
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Anti-cell surface endothelial antibodies in sera from cardiac and kidney transplant recipients: association with chronic rejection by Ferry, Berle L, Welsh, Ken I, Dunn, Michael J, Law, David, Proctor, Jeanette, Chapel, Helen, Yacoub, Magdi H, Rose, Marlene L

“…The aetiologies of accelerated or transplant-associated coronary artery disease (TxCAD) following cardiac transplantation and chronic rejection following renal…”
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Glutathione S-transferase polymorphisms and skin cancer after renal transplantation by Marshall, Sara E., Bordea, Cristina, Haldar, Neil A., Mullighan, Charles G., Wojnarowska, Fenella, Morris, Peter J., Welsh, Ken I.

“…Glutathione S-transferase polymorphisms and skin cancer after renal transplantation. Susceptibility to skin cancer after transplantation is multifactorial, and…”
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The presence of anti‐neutrophil antibodies reflects clinical and genetic heterogeneity within inflammatory bowel disease by Satsangi, Jack, Landers, Carol J., Welsh, Ken I., Koss, Konrad, Targan, Stephan, Jewell, Derek P.

“…A detailed investigation of the relationship between anti‐neutrophil cytoplasmic antibodies (ANCA) status, HLA genotype, and clinical patterns of inflammatory…”
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Independent contributions of HLA epitopes and killer inhibitory receptor expression to the functional alloreactive specificity of natural killer cells by Young, Neil T, Rust, Nigel A, Dallman, Margaret J, Cerundolo, Vincenzo, Morris, Peter J, Welsh, Ken I

“…Human NK cells express receptors (KIR) which inhibit lysis through binding to HLA class I on target cells. KIR expression in different individuals has not been…”
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Mapping the HLA association in Behçet's disease: A role for tumor necrosis factor polymorphisms? by Ahmad, Tariq, Wallace, Graham R., James, Teifi, Neville, Matt, Bunce, Mike, Mulcahy‐Hawes, Kim, Armuzzi, Alessandro, Crawshaw, Jonathan, Fortune, Farida, Walton, Robert, Stanford, Miles R., Welsh, Ken I., Marshall, Sara E., Jewell, Derek P.

“…Objective Experimental evidence suggests that inappropriate regulation of tumor necrosis factor α (TNFα) may play a role in the pathogenesis of Behçet's…”
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Endothelin axis polymorphisms in patients with scleroderma by Fonseca, Carmen, Renzoni, Elizabeth, Sestini, Piersante, Pantelidis, Panagiotis, Lagan, Anna, Bunn, Christopher, McHugh, Neil, Welsh, Ken I., Bois, Ron M. Du, Denton, Christopher P., Black, Carol, Abraham, D.

“…Objective To evaluate the distribution of polymorphisms in the endothelin 1 (EDN1), endothelin receptor A (EDNRA) and endothelin receptor B (EDNRB) genes in…”
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