Search Results - "WELLS, Clive"

Interleukin-9 production by type 2 innate lymphoid cells induces Paneth cell metaplasia and small intestinal remodeling by Yuan, Chengyin, Rayasam, Aditya, Moe, Alison, Hayward, Michael, Wells, Clive, Szabo, Aniko, Mackenzie, Andrew, Salzman, Nita, Drobyski, William R.

“…Paneth cell metaplasia (PCM) typically arises in pre-existing gastrointestinal (GI) diseases; however, the mechanistic pathway that induces metaplasia and…”
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Fatty Acid-Treated Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes Exhibit Adult Cardiomyocyte-Like Energy Metabolism Phenotypes by Horikoshi, Yuichi, Yan, Yasheng, Terashvili, Maia, Wells, Clive, Horikoshi, Hisako, Fujita, Satoshi, Bosnjak, Zeljko J, Bai, Xiaowen

“…Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs) (iPSC-CMs) are a promising cell source for myocardial regeneration, disease modeling…”
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A new iterative scheme for solving the discrete Smoluchowski equation by Smith, Alastair J., Wells, Clive G., Kraft, Markus

“…This paper introduces a new iterative scheme for solving the discrete Smoluchowski equation and explores the numerical convergence properties of the method for…”
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Ketamine induces toxicity in human neurons differentiated from embryonic stem cells via mitochondrial apoptosis pathway by Bosnjak, Zeljko J, Yan, Yasheng, Canfield, Scott, Muravyeva, Maria Y, Kikuchi, Chika, Wells, Clive W, Corbett, John A, Bai, Xiaowen

“…Ketamine is widely used for anesthesia in pediatric patients. Growing evidence indicates that ketamine causes neurotoxicity in a variety of developing animal…”
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Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids by Arzua, Thiago, Yan, Yasheng, Jiang, Congshan, Logan, Sarah, Allison, Reilly L., Wells, Clive, Kumar, Suresh N., Schäfer, Richard, Bai, Xiaowen

“…Maternal alcohol exposure during pregnancy can substantially impact the development of the fetus, causing a range of symptoms, known as fetal alcohol spectrum…”
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Modelling PAH curvature in laminar premixed flames using a detailed population balance model by Yapp, Edward K.Y., Wells, Clive G., Akroyd, Jethro, Mosbach, Sebastian, Xu, Rong, Kraft, Markus

“…A detailed population balance model, which includes the kinetic Monte Carlo-aromatic site (KMC-ARS) model for detailed polycyclic aromatic hydrocarbon (PAH)…”
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Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia by Pritchard, Jr, Kirkwood A, Jing, Xigang, Teng, Michelle, Wells, Clive, Jia, Shuang, Afolayan, Adeleye J, Jarzembowski, Jason, Day, Billy W, Naylor, Stephen, Hessner, Martin J, Konduri, G Ganesh, Teng, Ru-Jeng

“…Myeloperoxidase (MPO), oxidative stress (OS), and endoplasmic reticulum (ER) stress are increased in the lungs of rat pups raised in hyperoxia, an established…”
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Pepsin in Nonacidic Refluxate Can Damage Hypopharyngeal Epithelial Cells by Johnston, Nikki, Wells, Clive W., Samuels, Tina L., Blumin, Joel H.

“…Objectives: Studies using combined multichannel intraluminal impedance with pH monitoring reveal a role for nonacidic reflux in laryngopharyngeal symptoms and…”
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The In Vitro Replication Cycle of Achromobacter xylosoxidans and Identification of Virulence Genes Associated with Cytotoxicity in Macrophages by Pickrum, Adam M, Riegert, Molly O, Wells, Clive, Brockman, Kenneth, Frank, Dara W

“…Achromobacter xylosoxidans is an opportunistic pathogen implicated in a wide variety of human infections including the ability to colonize the lungs of cystic…”
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Rationale for Targeting Pepsin in the Treatment of Reflux Disease by Johnston, Nikki, Wells, Clive W., Samuels, Tina L., Blumin, Joel H.

“…Objectives: We undertook to 1) obtain unequivocal evidence to confirm or rebut our initial observations that pepsin is taken up by hypopharyngeal epithelial…”
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Factor VIII ectopically targeted to platelets is therapeutic in hemophilia A with high-titer inhibitory antibodies by Shi, Qizhen, Wilcox, David A, Fahs, Scot A, Weiler, Hartmut, Wells, Clive W, Cooley, Brian C, Desai, Drashti, Morateck, Patricia A, Gorski, Jack, Montgomery, Robert R

“…Inhibitory immune response to exogenously infused factor VIII (FVIII) is a major complication in the treatment of hemophilia A. Generation of such inhibitors…”
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On the equivalence of the FRW field equations and those of Newtonian cosmology by Wells, Clive G.

“…We present a simple argument to explain why the field equations of the Friedmann-Robertson-Walker (FRW) metric are equivalent to those of Newtonian cosmology…”
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Improving the reproducibility of diagnosing micrometastases and isolated tumor cells by Cserni, Gábor, Bianchi, Simonetta, Boecker, Werner, Decker, Thomas, Lacerda, Manuela, Rank, Fritz, Wells, Clive A.

“…BACKGROUND The latest edition of the tumor‐lymph node‐metastasis (TNM) classification of malignant tumors distinguishes between isolated tumor cells (pN0) and…”
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Correction to: Modeling alcohol-induced neurotoxicity using human induced pluripotent stem cell-derived three-dimensional cerebral organoids by Arzua, Thiago, Yan, Yasheng, Jiang, Congshan, Logan, Sarah, Allison, Reilly L., Wells, Clive, Kumar, Suresh N., Schäfer, Richard, Bai, Xiaowen

“…A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01214-z…”
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Curcumin and Anthocyanin Inhibit Pepsin-Mediated Cell Damage and Carcinogenic Changes in Airway Epithelial Cells by Samuels, Tina L., Pearson, Amy C. S., Wells, Clive W., Stoner, Gary D., Johnston, Nikki

“…Objectives Laryngopharyngeal reflux (LPR) is associated with inflammatory and neoplastic airway diseases. Gastric pepsin internalized by airway epithelial…”
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Receptor-Mediated Uptake of Pepsin by Laryngeal Epithelial Cells by Johnston, Nikki, Wells, Clive W., Blumin, Joel H., Toohill, Robert J., Merati, Albert L.

“…Objectives: Previous data suggest a mechanistic link between exposure to pepsin and cellular changes that lead to laryngopharyngeal disorders. Initial confocal…”
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Variations in sentinel node isolated tumour cells/micrometastasis and non-sentinel node involvement rates according to different interpretations of the TNM definitions by Cserni, Gábor, Bianchi, Simonetta, Vezzosi, Vania, van Diest, Paul, van Deurzen, Carolien, Sejben, István, Regitnig, Peter, Asslaber, Martin, Foschini, Maria P, Sapino, Anna, Castellano, Isabella, Callagy, Grace, Arkoumani, Evdokia, Kulka, Janina, Wells, Clive A

“…Abstract Breast cancers with nodal isolated tumour cells (ITC) and micrometastases are categorised as node-negative and node-positive, respectively, in the…”
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Differences in Expression of Mitochondrial Complexes Due to Genetic Variants May Alter Sensitivity to Radiation-Induced Cardiac Dysfunction by Schlaak, Rachel A, Frei, Anne, SenthilKumar, Gopika, Tsaih, Shirng-Wern, Wells, Clive, Mishra, Jyotsna, Flister, Michael J, Camara, Amadou K S, Bergom, Carmen

“…Radiation therapy is received by over half of all cancer patients. However, radiation doses may be constricted due to normal tissue side effects. In thoracic…”
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Junctional Adhesion Molecule-A Is Critical for the Formation of Pseudocanaliculi and Modulates E-cadherin Expression in Hepatic Cells by Konopka, Genevieve, Tekiela, Jackie, Iverson, Moriah, Wells, Clive, Duncan, Stephen A.

“…Hepatocytes are polarized epithelial cells whose function depends upon their ability to distinguish between the apical and basolateral surfaces that are…”
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Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study by Shaw, Emily Clare, Hanby, Andrew M, Wheeler, Kevin, Shaaban, Abeer M, Poller, David, Barton, Sheila, Treanor, Darren, Fulford, Laura, Walker, Rosemary A, Ryan, Deirdre, Lakhani, Sunil R, Wells, Clive A, Roche, Heather, Theaker, Jeffrey M, Ellis, Ian O, Jones, J Louise, Eccles, Diana M

“…(1) To compare the use of scanned virtual slide images (virtual microscopy) with glass slides (conventional microscopy) in the assessment of morphological…”
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