Search Results - "WELLS, Charles D"

6-month versus 36-month isoniazid preventive treatment for tuberculosis in adults with HIV infection in Botswana: a randomised, double-blind, placebo-controlled trial by Samandari, Taraz, Dr, Agizew, Tefera B, MD, Nyirenda, Samba, MD, Tedla, Zegabriel, MD, Sibanda, Thabisa, MBChB, Shang, Nong, PhD, Mosimaneotsile, Barudi, RN, Motsamai, Oaitse I, RN, Bozeman, Lorna, RN, Davis, Margarett K, MD, Talbot, Elizabeth A, MD, Moeti, Themba L, MBBS, Moffat, Howard J, FRCP, Kilmarx, Peter H, MD, Castro, Kenneth G, MD, Wells, Charles D, MD

“…Summary Background In accordance with WHO guidelines, people with HIV infection in Botswana receive daily isoniazid preventive therapy against tuberculosis…”
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HIV Infection and Multidrug-Resistant Tuberculosis—The Perfect Storm by Wells, Charles D, Cegielski, J. Peter, Nelson, Lisa J, Laserson, Kayla F, Holtz, Timothy H, Finlay, Alyssa, Castro, Kenneth G, Weyer, Karin

“…Background. Multidrug-resistant (MDR) tuberculosis (TB) has emerged as a global epidemic, with ∼ 425,000 new cases estimated to occur annually. The global…”
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Isoniazid, Rifampin, Ethambutol, and Pyrazinamide Pharmacokinetics and Treatment Outcomes Among a Predominantly HIV-Infected Cohort of Adults with Tuberculosis from Botswana by Chideya, Sekai, Winston, Carla A., Peloquin, Charles A., Bradford, William Z., Hopewell, Philip C., Wells, Charles D., Reingold, Arthur L., Kenyon, Thomas A., Moeti, Themba L., Tappero, Jordan W.

“…Background. We explored the association between antituberculosis drug pharmacokinetics and treatment outcomes among patients with pulmonary tuberculosis in…”
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Antiretroviral therapy during tuberculosis treatment and marked reduction in death rate of HIV-infected patients, Thailand by Akksilp, Somsak, Karnkawinpong, Opart, Wattanaamornkiat, Wanpen, Viriyakitja, Daranee, Monkongdee, Patama, Sitti, Walya, Rienthong, Dhanida, Siraprapasiri, Taweesap, Wells, Charles D, Tappero, Jordan W, Varma, Jay K

“…Antiretroviral therapy (ART) is lifesaving in patients with advanced HIV infection, but the magnitude of benefit in HIV-infected patients receiving…”
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Digital health technologies and adherence to tuberculosis treatment by Zaidi, Hussain Abbas, Wells, Charles D

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Tobramycin Solution for Inhalation Reduces Sputum Pseudomonas aeruginosa Density in Bronchiectasis by BARKER, ALAN F, COUCH, LESLIE, FIEL, STANLEY B, GOTFRIED, MARK H, ILOWITE, JONATHAN, MEYER, KEITH C, O'DONNELL, ANNE, SAHN, STEVEN A, SMITH, LEWIS J, STEWART, JACK O, ABUAN, TAMMY, TULLY, HEATHER, VAN DALFSEN, JILL, WELLS, CHARLES D, QUAN, JOANNE

“…We conducted a placebo-controlled, double-blind, randomized study to evaluate the microbiological efficacy and safety of inhaled tobramycin for treatment of…”
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HIV care and treatment factors associated with improved survival during TB treatment in Thailand: an observational study by Varma, Jay K, Nateniyom, Sriprapa, Akksilp, Somsak, Mankatittham, Wiroj, Sirinak, Chawin, Sattayawuthipong, Wanchai, Burapat, Channawong, Kittikraisak, Wanitchaya, Monkongdee, Patama, Cain, Kevin P, Wells, Charles D, Tappero, Jordan W

“…In Southeast Asia, HIV-infected patients frequently die during TB treatment. Many physicians are reluctant to treat HIV-infected TB patients with…”
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Delamanid improves outcomes and reduces mortality in multidrug-resistant tuberculosis by SKRIPCONOKA, Vija, DANILOVITS, Manfred, GEITER, Lawrence J, MANISSERO, Davide, WELLS, Charles D, PEHME, Lea, TOMSON, Tarmo, SKENDERS, Girts, KUMMIK, Tiina, CIRULE, Andra, LEIMANE, Vaira, KURVE, Anu, LEVINA, Klavdia

“…Multidrug-resistant and extensively drug-resistant tuberculosis (TB) are associated with worse treatment outcomes for patients, including higher mortality,…”
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Childhood TB epidemiology and treatment outcomes in Thailand: a TB active surveillance network, 2004 to 2006 by Lolekha, Rangsima, Anuwatnonthakate, Amornrat, Nateniyom, Sriprapa, Sumnapun, Surin, Yamada, Norio, Wattanaamornkiat, Wanpen, Sattayawuthipong, Wanchai, Charusuntonsri, Pricha, Sanguanwongse, Natpatou, Wells, Charles D, Varma, Jay K

“…Of the 9.2 million new TB cases occurring each year, about 10% are in children. Because childhood TB is usually non-infectious and non-fatal, national programs…”
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Long-term mortality assessment of multidrug-resistant tuberculosis patients treated with delamanid by Wells, Charles D, Gupta, Rajesh, Hittel, Norbert, Geiter, Lawrence J

“…Multidrug-resistant tuberculosis (MDR-TB) is a serious obstacle to TB control [1]. The disproportionately negative outcomes among patients with drug resistance…”
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Delamanid for Multidrug-Resistant Pulmonary Tuberculosis by Gler, Maria Tarcela, Skripconoka, Vija, Sanchez-Garavito, Epifanio, Xiao, Heping, Cabrera-Rivero, Jose L, Vargas-Vasquez, Dante E, Gao, Mengqiu, Awad, Mohamed, Park, Seung-Kyu, Shim, Tae Sun, Suh, Gee Young, Danilovits, Manfred, Ogata, Hideo, Kurve, Anu, Chang, Joon, Suzuki, Katsuhiro, Tupasi, Thelma, Koh, Won-Jung, Seaworth, Barbara, Geiter, Lawrence J, Wells, Charles D

“…In this report on the treatment of multidrug-resistant (MDR) tuberculosis, the authors found that delamanid, a novel anti-TB medication, led to more rapid…”
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Evaluating the potential impact of the new global plan to stop TB : Thailand, 2004-2005 by VARMA, Jay K, WIRIYAKITJAR, Daranee, YAMADA, Norio, AKARASEWI, Pasakorn, WELLS, Charles D, TAPPERO, Jordan W, NATENIYOM, Sriprapa, ANUWATNONTHAKATE, Amornrat, MONKONGDEE, Patama, SUMNAPAN, Surin, AKKSILP, Somsak, SATTAYAWUTHIPONG, Wanchai, CHARUNSUNTONSRI, Pricha, RIENTHONG, Somsak

“…WHO's new Global Plan to Stop TB 2006-2015 advises countries with a high burden of tuberculosis (TB) to expand case-finding in the private sector as well as…”
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Delamanid for Extensively Drug-Resistant Tuberculosis by Gupta, Rajesh, Gao, Mengqui, Cirule, Andra, Xiao, Heping, Geiter, Lawrence J, Wells, Charles D

“…Therapeutic options for extensively drug-resistant tuberculosis infection are limited. In this post-hoc analysis, a new drug, delamanid, shows some activity in…”
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HIV-associated TB in An Giang Province, Vietnam, 2001-2004: epidemiology and TB treatment outcomes by Thuy, Trinh Thanh, Shah, N Sarita, Anh, Mai Hoang, Nghia, Do Trong, Thom, Duong, Linh, Truong, Sy, Dinh Ngoc, Duong, Bui Duc, Chau, Luu Thi Minh, Mai, Phuong Thi Phoung, Wells, Charles D, Laserson, Kayla F, Varma, Jay K

“…Mortality is high in HIV-infected TB patients, but few studies from Southeast Asia have documented the benefits of interventions, such as co-trimoxazole (CTX),…”
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Pan-tuberculosis regimens: re-framing the argument by Gupta, Rajesh, Wells, Charles D

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Delamanid and QT prolongation in the treatment of multidrug-resistant tuberculosis by Gupta, Rajesh, Geiter, Lawrence J., Hafkin, Jeffrey, Wells, Charles D.

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Multidrug-resistant tuberculosis detection, Latvia by Skenders, Girts, Fry, Alicia M, Prokopovica, Inga, Greckoseja, Silvija, Broka, Lonija, Metchock, Beverly, Holtz, Timothy H, Wells, Charles D, Leimane, Vaira

“…To improve multidrug-resistant tuberculosis (MDR-TB) detection, we successfully introduced the rpoB gene mutation line probe assay into the national laboratory…”
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Rigorous Clinical Trial Design in Public Health Emergencies Is Essential by Ellenberg, Susan S, Keusch, Gerald T, Babiker, Abdel G, Edwards, Kathryn M, Lewis, Roger J, Lundgren, Jens D, Wells, Charles D, Wabwire-Mangen, Fred, McAdam, Keith P W J

“…Randomized clinical trials are the most reliable approaches to evaluating the effects of new treatments and vaccines. During the 2014-2015 West African Ebola…”
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Time to sputum culture conversion in multidrug-resistant tuberculosis : Predictors and relationship to treatment outcome by HOLTZ, Timothy H, STERNBERG, Maya, KAMMERER, Steve, LASERSON, Kayla F, RIEKSTINA, Vija, ZAROVSKA, Evija, SKRIPCONOKA, Vija, WELLS, Charles D, LEIMANE, Vaira

“…Conversion of sputum mycobacterial cultures from positive growth to negative growth of Mycobacterium tuberculosis in patients with pulmonary tuberculosis (TB)…”
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Reply to Jacob and Colebunders by Ellenberg, Susan S, Keusch, Gerald T, Babiker, Abdel G, Edwards, Kathryn M, Lewis, Roger J, Lundgren, Jens D, Wells, Charles D, Wabwire-Mangen, Fred, McAdam, Keith P W J

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