Search Results - "WELLING, P. A"

ATP is a Coupling Modulator of Parallel Na,K-ATPase-K-Channel Activity in the Renal Proximal Tubule by Tsuchiya, K., Wang, W., Giebisch, G., Welling, P. A.

“…A fundamental and essential property of nearly all salt-transporting epithelia is the tight parallel coupling between the magnitude of the K-conductive pathway…”
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Two channels for one job by Sansom, S.C., Welling, P.A.

“…The study by Rieg et al. is the first to examine potassium handling in BK–/– mice, thereby addressing many unanswered questions regarding the separate roles of…”
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Basolateral Membrane Expression of a K+Channel, Kir 2.3, is Directed by a Cytoplasmic COOH-Terminal Domain by Le Maout, Sophie, Welling, Paul A., Brejon, Manuel, Olsen, Olav, Merot, Jean

“…The inwardly rectifying potassium channel Kir 2.3 is specifically targeted and expressed on the basolateral membrane of certain renal epithelial cells. In the…”
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Molecular mechanisms of membrane polarity in renal epithelial cells by Campo, C, Mason, A, Maouyo, D, Olsen, O, Yoo, D, Welling, P A

“…Exciting discoveries in the last decade have cast light onto the fundamental mechanisms that underlie polarized trafficking in epithelial cells. It is now…”
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Aldosterone-dependent regulation of Na-K-ATPase subunit mRNA in the rat CCD: competitive PCR analysis by Tsuchiya, K, Giebisch, G, Welling, P A

“…In the cortical collecting duct (CCD), aldosterone increases the number of functionally active Na-K-adenosin-etriphosphatase (Na-K-ATPase) molecules by a…”
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Cell swelling activates basolateral membrane Cl and K conductances in rabbit proximal tubule by Welling, P A, O'Neil, R G

“…The ionic basis of volume regulation was assessed in the nonperfused rabbit proximal tubule (S2 segment) by use of simultaneous measurements of tubule volume…”
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Cell Surface Expression of the ROMK (Kir 1.1) Channel Is Regulated by the Aldosterone-induced Kinase, SGK-1, and Protein Kinase A by Yoo, Dana, Kim, Bo Young, Campo, Cristina, Nance, Latreece, King, Amanda, Maouyo, Djikolngar, Welling, Paul A

“…The Kir1.1 (ROMK) subtypes of inward rectifier K + channels mediate potassium secretion and regulate sodium chloride reabsorption in the kidney. The density of…”
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Aldosterone-mediated Na/K-ATPase expression is alpha 1 isoform specific in the renal cortical collecting duct by Welling, P A, Caplan, M, Sutters, M, Giebisch, G

“…In the renal cortical collecting duct (CCD), mineralocorticoid hormones, like aldosterone, augment the abundance of Na/K-ATPase molecules. It has been…”
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Importance of anion in hypotonic volume regulation of rabbit proximal straight tubule by Welling, P A, Linshaw, M A

“…Rabbit proximal straight tubules rapidly swell to a maximum volume when abruptly immersed into hypotonic medium. However, in a second, slower phase, termed…”
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Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK by Wade, J B, Welling, P A, Donowitz, M, Shenolikar, S, Weinman, E J

“…Na(+)/H(+) exchanger regulatory factor (NHERF) and NHERF2 are PDZ motif proteins that mediate the inhibitory effect of cAMP on Na(+)/H(+) exchanger 3 (NHE3) by…”
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Filled pore approximation: a theoretical framework for solute-solvent coupling in narrow water channels by Welling, D J, Welling, P A, Welling, L W

“…A phenomenological model is presented of water and solute transport that is applicable to water pores with radii less than approximately 2 A. This includes…”
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Effect of barium on cell volume regulation in rabbit proximal straight tubules by Welling, P A, Linshaw, M A, Sullivan, L P

“…Rabbit proximal straight tubules swell abruptly when exposed to hypotonic medium but then shrink in a few minutes as they approach their base-line volume…”
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Ionic conductive properties of rabbit proximal straight tubule basolateral membrane by Welling, P A, O'Neil, R G

“…The ionic conductive properties of the nonperfused rabbit proximal straight tubule (S2) basolateral membrane were assessed by microelectrode techniques. The…”
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Identification of G protein-coupled, inward rectifier potassium channel gene products from the rat anterior pituitary gland by Gregerson, K A, Flagg, T P, O'Neill, T J, Anderson, M, Lauring, O, Horel, J S, Welling, P A

“…Dopamine (DA) is a physiological regulator of PRL secretion, exerting tonic inhibitory control. DA activates an inward rectifier K(+) (IRK) channel in rat…”
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Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop by Ecelbarger, Carolyn A, Kim, Gheun-Ho, Knepper, Mark A, Liu, Jie, Tate, Margaret, Welling, Paul A, Wade, James B

“…The renal outer medullary potassium channel (ROMK) of the thick ascending limb (TAL) is a critical component of the counter-current multiplication mechanism…”
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A mutation linked with Bartter's syndrome locks Kir 1.1a (ROMK1) channels in a closed state by Flagg, T P, Tate, M, Merot, J, Welling, P A

“…Mutations in the inward rectifying renal K(+) channel, Kir 1.1a (ROMK), have been linked with Bartter's syndrome, a familial salt-wasting nephropathy. One…”
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Processing and Transport of ROMK1 Channel Is Temperature-Sensitive by Brejon, Manuel, Le Maout, Sophie, Welling, Paul A., Merot, Jean

“…To investigate the biosynthetic mechanisms involved in the expression of the renal epithelial inward rectifying K+ channel, ROMK1 (Kir1.1a), a six amino acid…”
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Basolateral Membrane Targeting of a Renal-Epithelial Inwardly Rectifying Potassium Channel from the Cortical Collecting Duct, CCD-IRK3, in MDCK Cells by Le Maout, Sophie, Brejon, Manuel, Olsen, Olav, Merot, Jean, Welling, Paul A.

“…We recently cloned an inward-rectifying K channel (Kir) cDNA, CCD-IRK3 (mKir 2.3), from a cortical collecting duct (CCD) cell line. Although this recombinant…”
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Klotho is highly expressed in the chief sites of regulated potassium secretion, and it is stimulated by potassium intake by Jung, Hyun Jun, Pham, Truyen D., Su, Xiao-Tong, Grigore, Teodora Veronica, Hoenderop, Joost G., Olauson, Hannes, Wall, Susan M., Ellison, David H., Welling, Paul A., Al-Qusairi, Lama

“…Klotho regulates many pathways in the aging process, but it remains unclear how it is physiologically regulated. Because Klotho is synthesized, cleaved, and…”
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The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Commentaries by SANSOM, S. C, WELLING, P. A, RIEG, T, VALLON, V, SAUSBIER, M, SAUSBIER, U, KAISSLING, B, RUTH, P, OSSWALD, H

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