Search Results - "WEIXIN JIN"
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TiO2 nanoparticles and multi-walled carbon nanotubes monitoring and bioremediation potential using ciliates Pseudocohnilembus persalinus
Published in Ecotoxicology and environmental safety (15-01-2020)“…In recent years, the release of nanomaterials pollutants to water bodies, to a great extent, attributed to anthropogenic activities. Their impacts on aquatic…”
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Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification
Published in mAbs (17-11-2019)“…Significant amounts of soluble product aggregates were observed during low-pH viral inactivation (VI) scale-up for an IgG4 monoclonal antibody (mAb IgG4-N1),…”
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3
Deep Learning for Seasonal Precipitation Prediction over China
Published in Journal of Meteorological Research (01-04-2022)“…Despite significant progress having been made in recent years, the forecast skill for seasonal precipitation over China remains limited. In this study, a…”
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4
Newly reconstructed Arctic surface air temperatures for 1979–2021 with deep learning method
Published in Scientific data (15-03-2023)“…A precise Arctic surface air temperature (SAT) dataset, that is regularly updated, has more complete spatial and temporal coverage, and is based on…”
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5
DOC45, a Novel DNA Damage–Regulated Nucleocytoplasmic ATPase That Is Overexpressed in Multiple Human Malignancies
Published in Molecular cancer research (01-01-2010)“…In this article, we report the characterization of a novel DNA damage–regulated gene, named DNA damage–regulated overexpressed in cancer 45 ( DOC45 ). Our…”
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6
RBEL1 Is a Novel Gene That Encodes a Nucleocytoplasmic Ras Superfamily GTP-binding Protein and Is Overexpressed in Breast Cancer
Published in The Journal of biological chemistry (28-12-2007)“…Rab family proteins are generally known as regulators of protein transport and trafficking. A number of Rab proteins have been implicated in cancer development…”
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Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest
Published in Oncogene (28-10-2004)“…RASSF1A is a putative tumor suppressor gene that is inactivated in a variety of human tumors. Expression of exogenous RASSF1A has been shown to inhibit tumor…”
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8
Effect of Bax deficiency on death receptor 5 and mitochondrial pathways during endoplasmic reticulum calcium pool depletion-induced apoptosis
Published in Oncogene (01-05-2003)“…Thapsigargin (TG), by inducing perturbations in cellular Ca(2+) homeostasis, can induce apoptosis, but the molecular mechanisms remain to be fully elucidated…”
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9
Effect of solution condition on the binding behaviors of monoclonal antibody and fusion protein therapeutics in Protein A chromatography
Published in Journal of Chromatography A (20-12-2022)“…•Fc-based proteins showed pH-dependent Protein A binding behaviors in basic solution conditions.•The binding capacity decreased by ∼30% from pH 9 to 10 on two…”
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10
Spatial-temporal characteristics analysis of solar irradiance forecast errors in Europe and North America
Published in Energy (Oxford) (15-06-2024)“…Accurate photovoltaic (PV) power forecast is crucial to power systems. Solar irradiance forecast is the fundamentals of PV power forecast. Current researches…”
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11
Hydrophobic property of cation-exchange resins affects monoclonal antibody aggregation
Published in Journal of Chromatography A (08-11-2020)“…•mAb structural stability decreases when lowering the solution pH from 6.0 to 4.5•mAb structural stability further decreases when bound on CEX…”
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12
Prediction and optimization of fruit quality of peach based on artificial neural network
Published in Journal of food composition and analysis (01-08-2022)“…Mineral nutrition is the material basis for growth and quality improvement of fruit trees. In this study, artificial neural networks (ANNs) and Multiple linear…”
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13
Molecular and Biological Characterization of Two New Species Causing Peach Shoot Blight in China
Published in Plant disease (01-01-2022)“…Peach shoot blight (PSB), which kills shoots, newly sprouted leaf buds, and peach fruits, has gradually increased over the last 10 years and resulted in 30 to…”
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14
Modeling scalability of impurity precipitation in downstream biomanufacturing
Published in Biotechnology progress (01-07-2024)“…Precipitation during the viral inactivation, neutralization and depth filtration step of a monoclonal antibody (mAb) purification process can provide…”
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15
Productivity improvement and charge variant modulation for intensified cell culture processes by adding a carboxypeptidase B (CpB) treatment step
Published in Biotechnology and bioengineering (01-09-2021)“…The goal of cell culture process intensification is to improve productivity while maintaining acceptable quality attributes. In this report, four processes,…”
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A CFD model for predicting protein aggregation in low‐pH virial inactivation for mAb production
Published in Biotechnology and bioengineering (01-11-2020)“…Significant amounts of soluble product aggregates were observed in the low‐pH viral inactivation (VI) operation during an initial scale‐up run for an…”
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17
Role of harvest depth filtration in controlling product-related impurities for a bispecific antibody
Published in Antibody therapeutics (01-10-2022)“…Abstract Background Bispecific antibodies (BsAb) belong to a novel antibody category with advantages over traditional mono-specific therapeutic antibodies…”
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18
Fruit quality prediction based on soil mineral element content in peach orchard
Published in Food science & nutrition (01-06-2022)“…Mineral nutrition of orchard soil is critical for the growth of fruit trees and improvement of fruit quality. In the present study, the effects of soil mineral…”
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Lappaol F, a novel anticancer agent isolated from plant arctium Lappa L
Published in Molecular cancer therapeutics (01-01-2014)“…In an effort to search for new cancer-fighting therapeutics, we identified a novel anticancer constituent, Lappaol F, from plant Arctium Lappa L. Lappaol F…”
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p53 mutation, EGFR gene amplification and loss of heterozygosity on chromosome 10, 17 p in human gliomas
Published in Chinese medical journal (01-07-2000)“…To further illustrate the roles of p53 gene, epidermal growth factor receptor (EGFR) gene and loss of heterozygosity (LOH) on chromosome 10 and 17 p in human…”
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