Search Results - "WEITZMAN, Jonathan"

Host–parasite interactions: an intimate epigenetic relationship by Cheeseman, Kevin, Weitzman, Jonathan B.

“…Summary The epigenetics of host–pathogen interactions is emerging as an interesting angle from which to study how parasites have evolved sophisticated…”
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The clever strategies used by intracellular parasites to hijack host gene expression by Villares, Marie, Berthelet, Jérémy, Weitzman, Jonathan B.

“…Intracellular pathogens need to develop sophisticated mechanisms to survive and thrive in the hostile environment within host cells. Unicellular, eukaryotic…”
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What’s the Damage? The Impact of Pathogens on Pathways that Maintain Host Genome Integrity by Weitzman, Matthew D., Weitzman, Jonathan B.

“…Maintaining genome integrity and transmission of intact genomes is critical for cellular, organismal, and species survival. Cells can detect damaged DNA,…”
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Cell geometry and the cytoskeleton impact the nucleo-cytoplasmic localisation of the SMYD3 methyltransferase by Pereira, David, Richert, Alain, Medjkane, Souhila, Hénon, Sylvie, Weitzman, Jonathan B.

“…Mechanical cues from the cellular microenvironment are converted into biochemical signals controlling diverse cell behaviours, including growth and…”
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The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network by Codato, Roberta, Perichon, Martine, Divol, Arnaud, Fung, Ella, Sotiropoulos, Athanassia, Bigot, Anne, Weitzman, Jonathan B., Medjkane, Souhila

“…The coordinated expression of myogenic regulatory factors, including MyoD and myogenin, orchestrates the steps of skeletal muscle development, from myoblast…”
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Intracellular Theileria Parasites PIN Down Host Metabolism by Medjkane, Souhila, Weitzman, Jonathan B

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OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes by Marsolier, Justine, Pineau, Sandra, Medjkane, Souhila, Perichon, Martine, Yin, Qinyan, Flemington, Erik, Weitzman, Matthew D, Weitzman, Jonathan B

“…The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in…”
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A reversible Warburg effect is induced by Theileria parasites to transform host leukocytes by Medjkane, Souhila, Weitzman, Jonathan B.

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SMYD3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9 by COCK-RADA, Alicia M, MEDJKANE, Souhila, JANSKI, Natacha, YOUSFI, Nadhir, PERICHON, Martine, CHAUSSEPIED, Marie, CHLUBA, Johanna, LANGSLEY, Gordon, WEITZMAN, Jonathan B

“…Upregulation of the matrix metalloproteinase (MMP)-9 plays a central role in tumor progression and metastasis by stimulating cell migration, tumor invasion,…”
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Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy by Villares, Marie, Lourenço, Nelly, Ktorza, Ivan, Berthelet, Jérémy, Panagiotou, Aristeidis, Richard, Aurélie, Amo, Angélique, Koziy, Yulianna, Medjkane, Souhila, Valente, Sergio, Fioravanti, Rossella, Pioche-Durieu, Catherine, Lignière, Laurent, Chevreux, Guillaume, Mai, Antonello, Weitzman, Jonathan B.

“…Intracellular pathogens develop elaborate mechanisms to survive within the hostile environments of host cells. Theileria parasites infect bovine leukocytes and…”
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Deciphering AP-1 Function in Tumorigenesis: Fra-ternizing on Target Promoters by Verde, Pasquale, Casalino, Laura, Talotta, Francesco, Yaniv, Moshe, Weitzman, Jonathan B.

“…Multi-gene families of transcription factors pose a formidable challenge to molecular and functional analysis. Dissecting distinct functions for individual…”
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Dynamic methylation of histone H3K18 in differentiating Theileria parasites by Cheeseman, Kevin, Jannot, Guillaume, Lourenço, Nelly, Villares, Marie, Berthelet, Jérémy, Calegari-Silva, Teresa, Hamroune, Juliette, Letourneur, Franck, Rodrigues-Lima, Fernando, Weitzman, Jonathan B.

“…Lysine methylation on histone tails impacts genome regulation and cell fate determination in many developmental processes. Apicomplexa intracellular parasites…”
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Putative SET-domain methyltransferases in Cryptosporidium parvum and histone methylation during infection by Sawant, Manasi, Benamrouz-Vanneste, Sadia, Meloni, Dionigia, Gantois, Nausicaa, Even, Gaël, Guyot, Karine, Creusy, Colette, Duval, Erika, Wintjens, René, Weitzman, Jonathan B., Chabe, Magali, Viscogliosi, Eric, Certad, Gabriela

“…Cryptosporidium parvum is a leading cause of diarrhoeal illness worldwide being a significant threat to young children and immunocompromised patients, but the…”
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The methylation landscape of tumour metastasis by Cock-Rada, Alicia, Weitzman, Jonathan B.

“…The metastatic cascade which leads to the death of cancer patients results from a multi‐step process of tumour progression caused by genetic and epigenetic…”
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Methylation of ESCRT-III components regulates the timing of cytokinetic abscission by Richard, Aurélie, Berthelet, Jérémy, Judith, Delphine, Advedissian, Tamara, Espadas, Javier, Jannot, Guillaume, Amo, Angélique, Loew, Damarys, Lombard, Berangere, Casanova, Alexandre G., Reynoird, Nicolas, Roux, Aurélien, Berlioz-Torrent, Clarisse, Echard, Arnaud, Weitzman, Jonathan B., Medjkane, Souhila

“…Abscission is the final stage of cytokinesis, which cleaves the intercellular bridge (ICB) connecting two daughter cells. Abscission requires tight control of…”
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Mutations in the TaPIN1 peptidyl prolyl isomerase gene in Theileria annulata parasites isolated in Sudan by Salim, Bashir, Chatanga, Elisha, Jannot, Guillaume, Mossaad, Ehab, Nakao, Ryo, Weitzman, Jonathan B.

“…The tick-borne parasite Theileria annulata is the causative agent of tropical theileriosis or Mediterranean theileriosis. Infection of bovine leukocytes by the…”
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Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism by Marsolier, Justine, Perichon, Martine, Weitzman, Jonathan B., Medjkane, Souhila

“…Metabolic reprogramming is an important feature of host–pathogen interactions and a hallmark of tumorigenesis. The intracellular apicomplexa parasite Theileria…”
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Lost in post-translation by Putois, Olivier, Villa, François, Weitzman, Jonathan B

“…Graphical Abstract The names we choose to describe or define biological concepts can have a huge impact on the way we think. It is time to reflect on whether…”
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TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility by Chaussepied, Marie, Janski, Natacha, Baumgartner, Martin, Lizundia, Regina, Jensen, Kirsty, Weir, William, Shiels, Brian R, Weitzman, Jonathan B, Glass, Elizabeth J, Werling, Dirk, Langsley, Gordon

“…Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible…”
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Epigenetic metaphors: an interdisciplinary translation of encoding and decoding by Raz, Aviad, Pontarotti, Gaëlle, Weitzman, Jonathan B.

“…Looking at the new and often disputed science of epigenetics, we examined the challenges faced by scientists when they communicate scientific research to the…”
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